Výsledky vyhledávání - "Agathe Verraes"

Akademický článek

The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions

Autor: Hugo Siegfried, Georges Farkouh, Rémi Le Borgne, Catherine Pioche-Durieu, Thaïs De Azevedo Laplace, Agathe Verraes, Lucien Daunas, Jean-Marc Verbavatz, Mélina L Heuzé

Publikováno v: eLife, Vol 13 (2024)

Cell motility processes highly depend on the membrane distribution of Phosphoinositides, giving rise to cytoskeleton reshaping and membrane trafficking events. Membrane contact sites serve as platforms for direct lipid exchange and calcium fluxes bet

Externí odkaz: https://doaj.org/article/c53c03f4ba7e4a009a3a45fe87d4aff5

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Akademický článek

Comparative study of commercially available and homemade anti-VAMP7 antibodies using CRISPR/Cas9-depleted HeLa cells and VAMP7 knockout mice [version 2; referees: 2 approved]

Autor: Agathe Verraes, Beatrice Cholley, Thierry Galli, Sebastien Nola

Publikováno v: F1000Research, Vol 7 (2019)

VAMP7 (vesicle-associated membrane protein) belongs to the intracellular membrane fusion SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptors) protein family. In this study, we used CRISPR/Cas9 genome editing technology to ge

Externí odkaz: https://doaj.org/article/13650a3d73954407a49ae306dc8c3c83

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The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions

Autor: Hugo Siegfried, Rémi Le Borgne, Catherine Durieu, Thaïs De Azevedo Laplace, Agathe Verraes, Lucien Daunas, Jean-Marc Verbavatz, Mélina L. Heuzé

Cell motility processes highly depend on the membrane distribution of Phosphoinositides (PInst), giving rise to cytoskeleton reshaping and membrane trafficking events. Membrane contact sites serve as platforms for lipid exchange and calcium fluxes be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4aa40fe060979dd31ecfb31e5ea57fa
https://doi.org/10.1101/2022.10.17.512434

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The induction of HAD-like phosphatases by multiple signaling pathways confers resistance to the metabolic inhibitor 2-deoxyglucose

Autor: Sébastien Léon, Anne Friedrich, Quentin Defenouillère, Agathe Verraes, Joseph Schacherer, Clotilde Laussel

Publikováno v: Science Signaling
Science Signaling, American Association for the Advancement of Science, 2019, 12 (597), pp.eaaw8000. ⟨10.1126/scisignal.aaw8000⟩

Cancer cells display an altered metabolism with an increased glycolysis and glucose uptake. Anti-cancer strategies targeting glycolysis through metabolic inhibitors have been considered. Particularly, the glucose analogue 2-deoxyglucose (2DG) is impo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39ce0223e5d1353dbbe589007b0a21a
https://pubmed.ncbi.nlm.nih.gov/31481524

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The regulation of HAD-like phosphatases by signaling pathways modulates cellular resistance to the metabolic inhibitor, 2-deoxyglucose

Autor: Sébastien Léon, Quentin Defenouillère, Joseph Schacherer, Anne Friedrich, Clotilde Laussel, Agathe Verraes

Publikováno v: Science Signaling
Science Signaling, American Association for the Advancement of Science, 2019, 12 (597), pp.eaaw8000. ⟨10.1126/scisignal.aaw8000⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b818b49c8bcf72a477faea1767770986

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Increased activity of the Vesicular Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor TI-VAMP/VAMP7 by Tyrosine Phosphorylation in the Longin Domain*

Autor: Sébastien Nola, Stefan T. Arold, Guan Wang, Aurelia Kuster, Damarys Loew, Florent Dingli, Thierry Galli, Alessandra Maria Casano, Agathe Verraes, Andrea Burgo

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (17), pp.11960-11972. ⟨10.1074/jbc.M112.415075⟩
Journal of Biological Chemistry, 2013, 288 (17), pp.11960-11972. ⟨10.1074/jbc.M112.415075⟩

International audience; Vesicular (v)- and target (t)-SNAREs play essential roles in intracellular membrane fusion through the formation of cytoplasmic α-helical bundles. Several v-SNAREs have a Longin N-terminal extension that, by promoting a close

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479c7c85ea28554b65d3b9d4739cc18f
https://europepmc.org/articles/PMC3636883/

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Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth

Autor: Letizia Lanzetti, Emmanuel Sotirakis, Marie-Christine Simmler, Thierry Galli, Jeremy C. Simpson, Agathe Verraes, Andrea Burgo, Christophe Chamot, Véronique Proux-Gillardeaux

Publikováno v: EMBO Reports
EMBO Reports, EMBO Press, 2009, 10 (10), pp.1117-24. ⟨10.1038/embor.2009.186⟩

International audience; The vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) tetanus neurotoxin-insensitive vesicle-associated membrane protein (TI-VAMP/VAMP7) was previously shown to mediate an exocytic pathway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a7e1df476de727a6083f2f9ba5edf9
https://hal.archives-ouvertes.fr/hal-00441596

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A Molecular Network for the Transport of the TI-VAMP/VAMP7 Vesicles from Cell Center to Periphery

Autor: Andrea Burgo, Etienne Formstecher, Philippe Bun, Thierry Galli, Maïté Coppey-Moisan, Véronique Proux-Gillardeaux, Ronald K.H. Liem, Agathe Verraes, Emmanuel Sotirakis, Alessandra Maria Casano

Publikováno v: Developmental Cell
Developmental Cell, Elsevier, 2012, 23 (1), pp.166-80. ⟨10.1016/j.devcel.2012.04.019⟩
ResearcherID

International audience; The compartmental organization of eukaryotic cells is maintained dynamically by vesicular trafficking. SNARE proteins play a crucial role in intracellular membrane fusion and need to be targeted to their proper donor or accept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6855465ea0a2b76d6b2fa404653a432

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Membrane Lipids Tune Synaptic Transmission by Direct Modulation of Presynaptic Potassium Channels

Autor: Christophe Mulle, Mario Carta, Joana Lourenço, Silvia Viana DaSilva, Nelson Rebola, Zsolt Szabo, Christophe Blanchet, Carsten Schultz, André Nadler, Agathe Verraes, Frederic Lanore

Publikováno v: Neuron
Neuron, Elsevier, 2014, 81 (4), pp.787-99. ⟨10.1016/j.neuron.2013.12.028⟩

International audience; Voltage-gated potassium (Kv) channels are involved in action potential (AP) repolarization in excitable cells. Exogenous application of membrane-derived lipids, such as arachidonic acid (AA), regulates the gating of Kv channel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15873bbc2bf04d8c238acb498173d7cc

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