Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Agathe León"'
Autor:
María J. Ruiz-de-León, María A. Jiménez-Sousa, Santiago Moreno, Marcial García, Mónica Gutiérrez-Rivas, Agathe León, Marta Montero-Alonso, Juan González-García, Salvador Resino, Norma Rallón, José M. Benito, Alejandro Vallejo, J.M. Benito, N. Rallón, C. Restrepo, N. Rodríguez, M. García, A. Cabello, M. Gorgolas, S. Resino, V. Briz, M.A. Jiménez, M.S. Vázquez, A. Fernández, P. García, M.A. Muñoz, J. Sánchez, J.L. Jiménez, D. Sepúlveda, I. García, I. Consuegra, A. León, M. Arnedo, M. Plana, N. Climent, F. García, E. Ruiz-Mateos, B. Domínguez, L. Tarancón, M. Rafii-El-Idrissi, M.J. Polaino, M. Genebat, P. Viciana, M. Leal, F. Vidal, E. Rodríguez, C. Viladés, J. Peraire, J. Romero, C Rodríguez, M. Vera, J. Esté, E. Ballana, M.A. Martínez, S. Franco, M. Nevot, A. Vallejo, S. Moreno, M. Pernas, C. Casado, C. López, L. Capa, M. Pérez, J. Alcami, R. Sanjuán, J.M. Cueva, R. Delgado, O. Sierra, A. Valenzuela
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 52, Iss 4, Pp 667-671 (2019)
Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137–0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.64
Externí odkaz:
https://doaj.org/article/725133f9f4b2422c80fc1f2b7486abb8
Autor:
Maria Bañó, Constanza Morén, Sergio Barroso, Diana Luz Juárez, Mariona Guitart-Mampel, Ingrid González-Casacuberta, Judith Canto-Santos, Ester Lozano, Agathe León, Enric Pedrol, Òscar Miró, Ester Tobías, Josep Mallolas, Jhon F. Rojas, Francesc Cardellach, Esteban Martínez, Gloria Garrabou
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Background: Mitochondrial genome has been used across multiple fields in research, diagnosis, and toxicogenomics. Several compounds damage mitochondrial DNA (mtDNA), including biological and therapeutic agents like the human immunodeficiency virus (H
Externí odkaz:
https://doaj.org/article/742f6e2c08eb40bea0a5c226c37accaf
Autor:
José M. Benito, María C. Ortiz, Agathe León, Luis A. Sarabia, José M. Ligos, María Montoya, Marcial Garcia, Ezequiel Ruiz-Mateos, Rosario Palacios, Alfonso Cabello, Clara Restrepo, Carmen Rodriguez, Jorge del Romero, Manuel Leal, María A. Muñoz-Fernández, José Alcamí, Felipe García, Miguel Górgolas, Norma Rallón, On behalf of ECRIS integrated in the Spanish AIDS Research Network
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mec
Externí odkaz:
https://doaj.org/article/03d5b5b4d6f8419c8c20967eec6cee93
Autor:
Mónica Gutiérrez-Rivas, María Ángeles Jiménez-Sousa, Norma Rallón, José Luis Jiménez, Clara Restrepo, Agathe León, Marta Montero-Alonso, Juan González-García, María Ángeles Muñoz-Fernández, José Miguel Benito, Salvador Resino, on Behalf of ECRIS Integrated in the Spanish AIDS Research Network
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Our aim was to analyze the relationship between plasma inflammatory biomarkers and CD4+ T-cells evolution in human immunodeficiency virus (HIV) elite controllers (HIV-ECs) with a suppressed viremia. We carried out a retrospective study in 30 HIV-ECs
Externí odkaz:
https://doaj.org/article/f96b4d342d8d4c72832be0b7b4447817
Autor:
Lander Egaña-Gorroño, Tuixent Escribà, Nicolas Boulanger, Alberto Crespo Guardo, Agathe León, Manel Enric Bargalló, Felipe Garcia, José María Gatell, Montserrat Plana, Mireia Arnedo, HIV Controllers Consortium of the AIDS Spanish Network
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106360 (2014)
BACKGROUND: The emerging relationship between microRNAs (miRNA) and viral-control is a topic of interest in the field of HIV. Host-genome might play an important role in the control of viremia. The aim of this study was to assess the specific miRNA p
Externí odkaz:
https://doaj.org/article/b62cec31941f4a3b93ae12454524ddc9
Autor:
Agathe León, César Cáceres, Emma Fernández, Paloma Chausa, Maite Martin, Carles Codina, Araceli Rousaud, Jordi Blanch, Josep Mallolas, Esteban Martinez, Jose L Blanco, Montserrat Laguno, Maria Larrousse, Ana Milinkovic, Laura Zamora, Neus Canal, Josep M Miró, Josep M Gatell, Enrique J Gómez, Felipe García
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14515 (2011)
BackgroundAntiretroviral therapy has changed the natural history of human immunodeficiency virus (HIV) infection in developed countries, where it has become a chronic disease. This clinical scenario requires a new approach to simplify follow-up appoi
Externí odkaz:
https://doaj.org/article/b8f71999e68c497b8eadc59c326f99a4
Autor:
Vicens Díaz-Brito, Constanza Lucero, E. Gonzalez, Felipe García, Agathe León, Alexy Inciarte, L Masfarre, Lorna Leal, J Garcia‐Pindado
Publikováno v:
HIV Medicine
Objectives Sexual assault (SA) is recognized as a public health problem of epidemic proportions. Guidelines recommend the administration of post-exposure prophylaxis (PEP) after an SA. However, few data are available about the feasibility of this str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd73a2a74b0b0721ded4b9f7a91e25f5
https://doi.org/10.1111/hiv.12797
https://doi.org/10.1111/hiv.12797
Autor:
Yusnelkis Milanés-Guisado, Cecilio López-Galíndez, Concepción Casado, Salvador Resino, Beatriz Dominguez-Molina, Pompeyo Viciana, Manuel Leal, Maria Pernas, Miguel Genebat, Ezequiel Ruiz-Mateos, Juan González-García, Carmen Rodríguez, Agathe León, Felipe García, Luis F. López-Cortés, Norma Rallón, Jorge del Romero, Laura Tarancon-Diez, José Miguel Benito
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Journal of the International AIDS Society
Digital.CSIC. Repositorio Institucional del CSIC
instname
Instituto de Salud Carlos III (ISCIII)
Journal of the International AIDS Society
Digital.CSIC. Repositorio Institucional del CSIC
instname
ECRIS integrated in the Spanish AIDS Research Network.
[Introduction] HIV‐controllers have the ability to spontaneously maintain viraemia at low or undetectable levels in the absence of antiretroviral treatment. Furthermore, HIV‐controllers
[Introduction] HIV‐controllers have the ability to spontaneously maintain viraemia at low or undetectable levels in the absence of antiretroviral treatment. Furthermore, HIV‐controllers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196f03685930672dc11aeeb79c2980f1
http://hdl.handle.net/20.500.12105/11081
http://hdl.handle.net/20.500.12105/11081
Autor:
Norma Rallón, Rosario Palacios-Muñoz, Miguel Górgolas, Julia Hillung, Clara Restrepo, Ezequiel Ruiz-Mateos, Rafael Sanjuán, Agathe León, José M. Cuevas, José M. Benito
Publikováno v:
International Journal of Medical Sciences
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Background APOBEC3H (A3H) gene presents variation at 2 positions (rs139297 and rs79323350) leading to a non-functional protein. So far, there is no information on the role played by A3H in spontaneous control of HIV. The aim of this study was to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f881f909fa9a44640e1eaf343d14dc35
https://doi.org/10.7150/ijms.22317
https://doi.org/10.7150/ijms.22317
Autor:
Carmen Rodríguez, Ezequiel Ruiz-Mateos, Manuel Leal, José Alcamí, Cecilio López-Galíndez, Pompeyo Viciana, José Miguel Benito, Jorge del Romero, Agathe León, Félix Gutiérrez, Felipe García, Beatriz Dominguez-Molina
Publikováno v:
Clinical Infectious Diseases. 62:1304-1309
BACKGROUND Human immunodeficiency virus (HIV) controllers have the striking ability to maintain viremia at extremely low or undetectable levels without antiretroviral treatment. Even though these patients have been widely studied, information about c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d07cbe624fd4ad6756a72df87704e0b
https://doi.org/10.1093/cid/ciw120
https://doi.org/10.1093/cid/ciw120