Use of a highly-sensitive rapid diagnostic test to screen for malaria in pregnancy in Indonesia

Autor: Vera T. Unwin, Rukhsana Ahmed, Rintis Noviyanti, Agatha M. Puspitasari, Retno A. S. Utami, Leily Trianty, Theda Lukito, Din Syafruddin, Jeanne R. Poespoprodjo, Maria A. Santana-Morales, Feiko O. Ter Kuile, Emily R. Adams

Publikováno v: Malaria Journal, Vol 19, Iss 1, Pp 1-8 (2020)

Abstract Background The sensitivity of rapid diagnostic tests (RDTs) for malaria is inadequate for detecting low-density, often asymptomatic infections, such as those that can occur when screening pregnant women for malaria. The performance of the Al

Externí odkaz: https://doaj.org/article/c7e681ab7d3846c0b5cfcc79054455b0

Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria

Autor: Stephanie I Studniberg, Lisa J Ioannidis, Retno A S Utami, Leily Trianty, Yang Liao, Waruni Abeysekera, Connie S N Li‐Wai‐Suen, Halina M Pietrzak, Julie Healer, Agatha M Puspitasari, Dwi Apriyanti, Farah Coutrier, Jeanne R Poespoprodjo, Enny Kenangalem, Benediktus Andries, Pak Prayoga, Novita Sariyanti, Gordon K Smyth, Alan F Cowman, Ric N Price, Rintis Noviyanti, Wei Shi, Alexandra L Garnham, Diana S Hansen

Publikováno v: Molecular Systems Biology, Vol 18, Iss 4, Pp 1-25 (2022)

Abstract Clinical immunity to P. falciparum malaria is non‐sterilizing, with adults often experiencing asymptomatic infection. Historically, asymptomatic malaria has been viewed as beneficial and required to help maintain clinical immunity. Emergin

Externí odkaz: https://doaj.org/article/9505b794f7c44aa7b62ddf1faadc14f6

High-dimensional mass cytometry identifies T cell and B cell signatures predicting reduced risk of Plasmodium vivax malaria

Autor: Benediktus Andries, Leily Trianty, Emily M. Eriksson, Ann Ly, Stephanie Studniberg, Ric N. Price, Dwi Apriyanti, Agatha M. Puspitasari, Halina M. Pietrzak, Farah N. Coutrier, Lisa J Ioannidis, Alan F. Cowman, Waruni Abeysekera, Enny Kenangalem, Julie Healer, Retno Ayu Setya Utami, Gordon K. Smyth, Pak Prayoga, Dylan Sheerin, Connie S N Li-Wai-Suen, Diana S. Hansen, Rintis Noviyanti, Jeanne Rini Poespoprodjo, Novita Sariyanti

Publikováno v: JCI Insight

IFN-γ–driven responses to malaria have been shown to modulate the development and function of T follicular helper (TFH) cells and memory B cells (MBCs), with conflicting evidence of their involvement in the induction of antibody responses required

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be78f91cc0eb40130a8f58fccf28eeb1
https://doi.org/10.1172/jci.insight.148086

Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region

Autor: Maria Endang Sumiwi, Farah N. Coutrier, Najia Karim Ghanchi, Nancy Dian Anggraeni, Nadia Fadila, Hidayat Trimarsanto, Leily Trianty, Jutta Marfurt, Ferdinand Laihad, Duoquan Wang, Ric N. Price, Sasha Siegel, Olivo Miotto, Alyssa E. Barry, Rintis Noviyanti, Nguyen Thuy-Nhien, Yaobao Liu, Kesang Wangchuck, Fatema Tuj Johora, Sarah Auburn, Retno A. S. Utami, Agatha M. Puspitasari, Livingstone Tavul, Huynh Hong Quang

Publikováno v: Malaria Journal
Malaria Journal, Vol 19, Iss 1, Pp 1-20 (2020)

The Asia–Pacific region faces formidable challenges in achieving malaria elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites can provide important information on malaria transmission and adaptation, which can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28753e1b1e6291240c263070d95258e9
https://ora.ox.ac.uk/objects/uuid:1bab2d7a-b4d4-49d9-8334-86d8ac6ad257

Positron emission tomography and magnetic resonance imaging in experimental human malaria to identify organ-specific changes in morphology and glucose metabolism: A prospective cohort study

Autor: Rintis Noviyanti, Agatha M. Puspitasari, Papa Alioune Ndour, Nurjati Chairani Siregar, Benediktus Andries, Benoit Henry, Leo Leonardo, Dwi Apriyanti, Fabrice Chrétien, Bruce Russell, Nur I. Margyaningsih, Carmen Fernandez-Becerra, Aurélie Fricot, Matthias Marti, Nicholas M. Anstey, Tsin W. Yeo, Valentine Brousse, Labibah Qotrunnada, Ric N. Price, David Hardy, Pierre Buffet, Hernando A. del Portillo, Leily Trianty, Pak Prayoga, Enny Kenangalem, Elamaran Meibalan, Jeanne Rini Poespoprodjo, Innocent Safeukui, Putu A. I. Wardani, Tonia Woodberry, Steven Kho, Gabriela Minigo

Publikováno v: PLoS Medicine
PLoS Medicine, 2021, 18 (5), pp.e1003632. ⟨10.1371/journal.pmed.1003632⟩
PLoS Medicine, Public Library of Science, 2021, 18 (5), pp.e1003632. ⟨10.1371/journal.pmed.1003632⟩
PLoS Medicine, Vol 18, Iss 5, p e1003632 (2021)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Background A very large biomass of intact asexual-stage malaria parasites accumulates in the spleen of asymptomatic human individuals infected with Plasmodium vivax. The mechanisms underlying this intense tropism are not clear. We hypothesised that i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c1d3cc1e80eb685647fe8a657f84fd
https://doi.org/10.1371/journal.pmed.1003632