Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Agata Rode"'
Autor:
Dominik Sturm, David Capper, Felipe Andreiuolo, Marco Gessi, Christian Kölsche, Annekathrin Reinhardt, Philipp Sievers, Annika K. Wefers, Azadeh Ebrahimi, Abigail K. Suwala, Gerrit H. Gielen, Martin Sill, Daniel Schrimpf, Damian Stichel, Volker Hovestadt, Bjarne Daenekas, Agata Rode, Stefan Hamelmann, Christopher Previti, Natalie Jäger, Ivo Buchhalter, Mirjam Blattner-Johnson, Barbara C. Jones, Monika Warmuth-Metz, Brigitte Bison, Kerstin Grund, Christian Sutter, Steffen Hirsch, Nicola Dikow, Martin Hasselblatt, Ulrich Schüller, Nicolas U. Gerber, Christine L. White, Molly K. Buntine, Kathryn Kinross, Elizabeth M. Algar, Jordan R. Hansford, Nicholas G. Gottardo, Pablo Hernáiz Driever, Astrid Gnekow, Olaf Witt, Hermann L. Müller, Gabriele Calaminus, Gudrun Fleischhack, Uwe Kordes, Martin Mynarek, Stefan Rutkowski, Michael C. Frühwald, Christof M. Kramm, Andreas von Deimling, Torsten Pietsch, Felix Sahm, Stefan M. Pfister, David. T. W. Jones
Publikováno v:
Nature Medicine. 29:917-926
The large diversity of central nervous system (CNS) tumor types in children and adolescents results in disparate patient outcomes and renders accurate diagnosis challenging. In this study, we prospectively integrated DNA methylation profiling and tar
Autor:
Marc Zapatka, Manasi Ratnaparkhe, Yosef Buganim, Shulamit Sebban, Peter Lichter, Milena Simovic, Peter Schmezer, Anna Jauch, Thorsten Kolb, Daniel Haag, Agata Rode, Aurélie Ernst, Umar Khalid, Frauke Devens, Michaela Hergt, John Wong
In vitro assays for clustered DNA lesions will facilitate the analysis of the mechanisms underlying complex genome rearrangements such as chromothripsis, including the recruitment of repair factors to sites of DNA double-strand breaks. We present a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a364a8104697ba22bed362e72946f29b
https://doi.org/10.1101/2020.04.27.064105
https://doi.org/10.1101/2020.04.27.064105
Autor:
Jessica I. Hoell, Stefan Zielen, Peter Lichter, Wojciech Młynarski, Krystyna H. Chrzanowska, Aurélie Ernst, Marc Zapatka, Mario Hlevnjak, Takashi Taga, Barbara C. Worst, Agata Pastorczak, Reiner Siebert, Andrey Korshunov, Frauke Devens, Volker Hovestadt, Ute Fischer, Joachim B. Kunz, Masatoshi Takagi, David T.W. Jones, Andreas E. Kulozik, Christof M. Kramm, Eberhard Maass, Agata Rode, Jules P.P. Meijerink, Michaela Nathrath, Eugen Tausch, Till Milde, Jan Loeffen, Manasi Ratnaparkhe, Gudrun Göhring, Shlomi Constantini, Kendra K. Maass, Stefan M. Pfister, Thorsten Kolb, Anna Jauch, Jan O. Korbel, Brigitte Schlegelberger, Stephanie Sungalee
Publikováno v:
ResearcherID
Leukemia, 31(10), 2048-2056. Nature Publishing Group
Leukemia, 31(10), 2048-2056. Nature Publishing Group
Recent developments in sequencing technologies led to the discovery of a novel form of genomic instability, termed chromothripsis. This catastrophic genomic event, involved in tumorigenesis, is characterized by tens to hundreds of simultaneously acqu
Autor:
Dominik Sturm, David T.W. Jones, David Capper, Felipe Andreiuolo, Nicolas U. Gerber, Stefan M. Pfister, Stefan Rutkowski, Felix Sahm, Agata Rode, Marco Gessi, Torsten Pietsch, Christof M. Kramm, Nicholas G. Gottardo, Steffen Hirsch, Andreas von Deimling, Brigitte Bison
Publikováno v:
Neuro-Oncology
The large variety of CNS tumor entities affecting children and adolescents, some of which are exceedingly rare, results in very diverging patient outcomes and renders accurate diagnosis challenging. To assess the diagnostic utility of routine DNA met
Autor:
Billy Michael Chelliah Jebaraj, Kristian W. Pajtler, Jennifer Edelmann, Uri Tabori, Marcel Kool, Stephan Stilgenbauer, Aurélie Ernst, Andrey Korshunov, Pedro Castelo-Branco, Katharina I. Deeg, Stefan M. Pfister, Sebastian Bender, Peter Lichter, Marc Zapatka, Kendra K. Maass, David T.W. Jones, Agata Rode, Sebastian Brabetz, Karsten Rippe, Frauke Devens, Michael A. Tainsky, David Malkin, Cindy Zhang, Volker Hovestadt, Susanne Gröbner
Publikováno v:
International Journal of Cancer. 138:2905-2914
Chromothripsis is a recently discovered form of genomic instability, characterized by tens to hundreds of clustered DNA rearrangements resulting from a single dramatic event. Telomere dysfunction has been suggested to play a role in the initiation of
Publikováno v:
International Journal of Cancer. 138:2322-2333
In 2011, a novel form of genome instability was reported by Stephens et al., characterized by tens to hundreds of locally clustered rearrangements affecting one or a few chromosome(s) in cancer cells. This phenomenon, termed chromothripsis, is likely
Autor:
Felix Sahm, Monika Warmuth-Metz, Torsten Pietsch, Agata Rode, Felipe Andreiuolo, Brigitte Bison, Marco Gessi, Stefan M. Pfister, Dominik Sturm, Stefan Rutkowski, Kerstin Grund, Steffen Hirsch, David T.W. Jones, Andreas von Deimling
Publikováno v:
Neuro-Oncology. 21:ii82-ii82
There is a broad variety of CNS tumor entities that can affect children and adolescents, associated with divergent clinical outcomes. We have recently proposed a DNA methylation-based classification to distinguish biologically distinct CNS tumor clas
Autor:
Stefan Rutkowski, Felix Sahm, Agata Rode, Dominik Sturm, Brigitte Bison, David T.W. Jones, Andreas von Deimling, Torsten Pietsch, David Capper, Monika Warmuth-Metz, Stefan M. Pfister, Kerstin Grund, Felipe Andreiuolo, Marco Gessi
Publikováno v:
Neuro-Oncology. 20:i181-i181
Children can be affected by a large variety of CNS tumor entities with very divergent outcomes, some of which are exceedingly rare. DNA methylation analysis is a powerful tool to distinguish biologically distinct CNS tumor classes within and across h
Autor:
Agata, Rode, Kendra Korinna, Maass, Karolin Viktoria, Willmund, Peter, Lichter, Aurélie, Ernst
Publikováno v:
International journal of cancer. 138(10)
In 2011, a novel form of genome instability was reported by Stephens et al., characterized by tens to hundreds of locally clustered rearrangements affecting one or a few chromosome(s) in cancer cells. This phenomenon, termed chromothripsis, is likely
Autor:
Frauke Devens, Volker Hovestadt, Jan Loeffen, Manasi Ratnaparkhe, Masatoshi Takagi, Mario Hlevnjak, Jules P.P. Meijerink, Eberhard Maass, Michaela Nathrath, Brigitte Schlegelberger, Takashi Taga, Agata Rode, Christof M. Kramm, Andrey Korshunov, Joachim B. Kunz, Jessica I. Hoell, Andreas E. Kulozik, Peter Lichter, Barbara C. Worst, Stefan Zielen, Krystyna H. Chrzanowska, Jan O. Korbel, Stefan M. Pfister, David T.W. Jones, Agata Pastorczak, Anna Jauch, Eugen Tausch, Till Milde, Shlomi Constantini, Gudrun Goehring, Ute Fischer, Thorsten Kolb, Stephanie Sungalee, Wojciech Młynarski, Aurélie Ernst, Reiner Siebert, Marc Zapatka, Kendra K. Maass
Publikováno v:
Cancer Research. 77:509-509
Recent developments in sequencing technologies lead to the discovery of a novel form of genome instability, termed chromothripsis. This catastrophic genomic event, involved in cancer formation, is characterized by tens to hundreds of locally clustere