Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Agata Paneth"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Nowadays, dermatophyte infections are relatively easy to cure, especially since the introduction of orally administered antifungals such as terbinafine and itraconazole. However, these drugs may cause side effects due to liver damage or thei
Externí odkaz:
https://doaj.org/article/970893d52b834388ae183c99a822b55f
Autor:
Lidia Węglińska, Adrian Bekier, Nazar Trotsko, Barbara Kaproń, Tomasz Plech, Katarzyna Dzitko, Agata Paneth
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2621-2634 (2022)
A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and sulfadiazine (SDZ). We previously reported on the identification of the com
Externí odkaz:
https://doaj.org/article/79d58e45c8734949b193085685825372
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Confinement can result in unusual properties leading to new, exciting discoveries in the nano-realm. One such consequence of confinement at the nanoscale is extremally large isotopic fractionation, especially at sub-van der Waals distances.
Externí odkaz:
https://doaj.org/article/e057500f47c1413da079e3c3fad7bfaf
Publikováno v:
Molecules, Vol 28, Iss 13, p 5287 (2023)
The main aim of the current project was to investigate the effect of the linker size in 4-alkyl-5-aryl-1,2,4-triazole-3-thione derivatives, known as a group of antiepileptic drug candidates, on their affinity towards voltage-gated sodium channels (VG
Externí odkaz:
https://doaj.org/article/22bde85ae03d40b68e61b26d9ee565ca
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1145-1164 (2021)
We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at N1 position, on highly virulent RH strain of Toxoplasma gondii. Among them, the highest in vitro anti-Toxoplasma activity was found with the
Externí odkaz:
https://doaj.org/article/c469cec21766439e99c28e34fbdb3bfc
Autor:
Monika Rola, Jakub Krassowski, Julita Górska, Anna Grobelna, Wojciech Płonka, Agata Paneth, Piotr Paneth
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256834 (2021)
The current pandemic outbreak clearly indicated the urgent need for tools allowing fast predictions of bioactivity of a large number of compounds, either available or at least synthesizable. In the computational chemistry toolbox, several such tools
Externí odkaz:
https://doaj.org/article/46b2edb30ec148f6b53976bcf1873f07
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 4, Pp 568-577 (2018)
A series of new (2,4-dioxothiazolidin-5-yl/ylidene)acetic acid derivatives with thiazolidine-2,4-dione, rhodanine and 2-thiohydantoin moiety (28–65) were synthesized by the reaction of (2,4-dioxothiazolidin-5-yl/ylidene)acetic acid chlorides with 5
Externí odkaz:
https://doaj.org/article/e1d5c79143e144d1bb04b3d5645dfc80
Autor:
Nazar Trotsko, Agata Przekora, Justyna Zalewska, Grażyna Ginalska, Agata Paneth, Monika Wujec
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 17-24 (2018)
In our present research, we synthesised new thiazolidine-2,4-diones (12–28). All the newly synthesised compounds were evaluated for antiproliferative and antibacterial activity. Antiproliferative evaluation was carried out using normal human skin f
Externí odkaz:
https://doaj.org/article/da7a4e8d1fbb4168867a0ee7cf3df5cc
Autor:
Adrian Bekier, Malwina Kawka, Jakub Lach, Jarosław Dziadek, Agata Paneth, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek
Publikováno v:
Cells, Vol 10, Iss 12, p 3476 (2021)
Mycobacterium tuberculosis (Mtb) is an intracellular pathogenic bacterium and the causative agent of tuberculosis. This disease is one of the most ancient and deadliest bacterial infections, as it poses major health, social and economic challenges at
Externí odkaz:
https://doaj.org/article/80154c38a6024a128e49dc4d9b962750
Autor:
Lidia Węglińska, Adrian Bekier, Katarzyna Dzitko, Barbara Pacholczyk-Sienicka, Łukasz Albrecht, Tomasz Plech, Piotr Paneth, Agata Paneth
Publikováno v:
Cells, Vol 10, Iss 5, p 1053 (2021)
Congenital and acquired toxoplasmosis caused by the food- and water-born parasite Toxoplasma gondii (T. gondii) is one of the most prevalent zoonotic infection of global importance. T. gondii is an obligate intracellular parasite with limited capacit
Externí odkaz:
https://doaj.org/article/0073550043ed4ae7a51c58b22887d0d2