Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Agata N. Burska"'
Autor:
Agata N. Burska, Bayansulu Ilyassova, Aruzhan Dildabek, Medina Khamijan, Dinara Begimbetova, Ferdinand Molnár, Dos D. Sarbassov
Publikováno v:
Cells, Vol 11, Iss 21, p 3454 (2022)
The turn-on mutations of the KRAS gene, coding a small GTPase coupling growth factor signaling, are contributing to nearly 25% of all human cancers, leading to highly malignant tumors with poor outcomes. Targeting of oncogenic KRAS remains a most cha
Externí odkaz:
https://doaj.org/article/63c40894e1334db2ad76639131414761
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
The treatment of rheumatoid arthritis (RA) has been transformed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARD) and more recently, targeted synthetic DMARD (tsDMARD) therapies in the form of janus-kinase inhibitors.
Externí odkaz:
https://doaj.org/article/ca0b57f4014945c89d6d1461d71c76f8
Autor:
Payal Ganguly, Jehan J. El-Jawhari, Agata N. Burska, Frederique Ponchel, Peter V. Giannoudis, Elena A. Jones
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Uncultured mesenchymal stromal cells (MSCs) are increasingly used in therapies; however, the effects of donor age on their biological characteristics and gene expression remain unclear. The aim of this study was to investigate age-related changes in
Externí odkaz:
https://doaj.org/article/76dd14f35c19453c902a07decd843746
Autor:
Payal Ganguly, Agata N. Burska, Charlotte L.M. Davis, Jehan J. El-Jawhari, Peter V. Giannoudis, Elena A. Jones
Publikováno v:
Biomedicines, Vol 8, Iss 7, p 214 (2020)
Skeletal aging is associated with reduced proliferative potential of bone marrow (BM) multipotential stromal cells (MSCs). Recent data suggest the involvement of type 1 interferon (IFN1) signalling in hematopoietic stem cell (HSC) senescence. Conside
Externí odkaz:
https://doaj.org/article/7aefccf997f54587938085fc888404e0
Autor:
Payal Ganguly, Jehan J. El-Jawhari, Peter V. Giannoudis, Agata N. Burska, Frederique Ponchel, Elena A. Jones
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Aging at the cellular level is a complex process resulting from accumulation of various damages leading to functional impairment and a reduced quality of life at the level of the organism. With a rise in the elderly population, the worldwide incidenc
Externí odkaz:
https://doaj.org/article/bc7455352c34496eba061d240ef72afd
Autor:
Agata N. Burska, Laura Hunt, Marjorie Boissinot, Rocky Strollo, Brent J. Ryan, Ed Vital, Ahuva Nissim, Paul G. Winyard, Paul Emery, Frederique Ponchel
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Autoantibodies have been associated with human pathologies for a long time, particularly with autoimmune diseases (AIDs). Rheumatoid factor (RF) is known since the late 1930s to be associated with rheumatoid arthritis (RA). The discovery of anticitru
Externí odkaz:
https://doaj.org/article/80e786233228489fb880b883062906b4
Autor:
Dinara Begimbetova, Assiya Kukanova, Fatima Fazyl, Kenzhekyz Manekenova, Talgat Omarov, Agata N. Burska, Medina Khamijan, Alexandr Gulyayev, Bakytgul Yermekbayeva, Abay Makishev, Timur Saliev, Kanat Batyrbekov, Chokan Aitbayev, Zhanat Spatayev, Dos Sarbassov
Publikováno v:
BioMed research international. 2022
Background. Kirsten rat sarcoma (KRAS) protein is an essential contributor to the development of pancreatic ductal adenocarcinoma (PDAC). KRAS G12D and G12V mutant tumours are significant challenges in cancer therapy due to high resistance to the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecedea2aaed5996e069e96a0dad6882d
https://pubmed.ncbi.nlm.nih.gov/36619305
https://pubmed.ncbi.nlm.nih.gov/36619305
Autor:
Frederique Ponchel, Sarah Churchman, Jehan J. El-Jawhari, Agata N. Burska, Philip Chambers, Edward M. Vital, Yasser M. El-Sherbiny, Elena Jones, Philip G. Conaghan, Vincent Goeb, Paul Emery
Publikováno v:
Clinical and Experimental Rheumatology. 39:253-262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ac918c7c9862fa855edd7a8b1d2a82
https://doi.org/10.55563/clinexprheumatol/j6t7cj
https://doi.org/10.55563/clinexprheumatol/j6t7cj
Autor:
Frederique Ponchel, Myrthe A.M. van Delft, Xuanxiao Xie, Agata N. Burska, Laurence Duquenne, Leendert A. Trouw, Paul Emery
Publikováno v:
Clinical and Experimental Rheumatology. 39:146-150
ACR/EULAR-2010 classification criteria for rheumatoid arthritis (RA) rely heavily on the presence of anti-citrullinated peptide antibody (ACPA). The role of anti-carbamylated protein antibodies (anti-CarP) in this context is uncertain. We aimed to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a3d8c9702dc43fafa8333812dcbb90
https://doi.org/10.55563/clinexprheumatol/u891rd
https://doi.org/10.55563/clinexprheumatol/u891rd
Autor:
Agata N, Burska, Jehan J, El-Jawhari, Jianhua, Wu, Richard J, Wakefield, Helena, Marzo-Ortega, Philip G, Conaghan, Paul, Emery, Frederique, Ponchel, Jane E, Freeston
Publikováno v:
Clinical and experimental rheumatology. 39(3)
The aim of this study was to establish whether serum RANKL levels in early inflammatory arthritis (IA) were associated with rheumatoid arthritis (RA) diagnosis at follow-up, and to evaluate the added value of RANKL for RA diagnosis.Serum from 298 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e351ab027607878a73d4ef2371ce75b
https://pubmed.ncbi.nlm.nih.gov/32828147
https://pubmed.ncbi.nlm.nih.gov/32828147