Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Agata N, Makar"'
Autor:
Agata N. Makar, Alina Boraman, Peter Mosen, Joanne E. Simpson, Jair Marques, Tim Michelberger, Stuart Aitken, Ann P. Wheeler, Dominic Winter, Alex von Kriegsheim, Noor Gammoh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. Using a CRISPR/Cas9-based screen,
Externí odkaz:
https://doaj.org/article/6883251db50c4cf790616ebe8bd9529f
Publikováno v:
The FEBS Journal. 287:4806-4821
Autophagosomes are vital organelles required to facilitate the lysosomal degradation of cytoplasmic cargo, thereby playing an important role in maintaining cellular homeostasis. A number of autophagy-related (ATG) protein complexes are recruited to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f746c1c5acb372b402ee73dfb5fee0f5
https://doi.org/10.1111/febs.15334
https://doi.org/10.1111/febs.15334
Autor:
Noor Gammoh, Agata N. Makar
Publikováno v:
Molecular Cell
Makar, A & Gammoh, N 2020, ' Autophagy Brings an END to Aberrant Endocytosis ', Molecular Cell . https://doi.org/10.1016/j.molcel.2020.11.020
Makar, A & Gammoh, N 2020, ' Autophagy Brings an END to Aberrant Endocytosis ', Molecular Cell . https://doi.org/10.1016/j.molcel.2020.11.020
Summary Autophagy eliminates cytoplasmic content selected by autophagy receptors, which link cargo to the membrane-bound autophagosomal ubiquitin-like protein Atg8/LC3. Here, we report a selective autophagy pathway for protein condensates formed by e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa53a31028f68e048d222e7a97ce7d4
https://doi.org/10.1016/j.molcel.2020.11.020
https://doi.org/10.1016/j.molcel.2020.11.020
Publikováno v:
The EMBO Journal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::8e6b035d6da8bf924abbfe4f950633a1
Autor:
Leo J, Dudley, Ainara G, Cabodevilla, Agata N, Makar, Martin, Sztacho, Tim, Michelberger, Joseph A, Marsh, Douglas R, Houston, Sascha, Martens, Xuejun, Jiang, Noor, Gammoh
Publikováno v:
The EMBO Journal
Membrane targeting of autophagy‐related complexes is an important step that regulates their activities and prevents their aberrant engagement on non‐autophagic membranes. ATG16L1 is a core autophagy protein implicated at distinct phases of autoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c6e710a6544b938811cd065b813646f
https://pubmed.ncbi.nlm.nih.gov/30936093
https://pubmed.ncbi.nlm.nih.gov/30936093