Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Agata Kurowski"'
Autor:
Stanley E. Strawbridge, Agata Kurowski, Elena Corujo-Simon, Alastair N. Fletcher, Jennifer Nichols, Alexander G. Fletcher
Publikováno v:
Biology Open, Vol 12, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/26280dd9559c4df3aea7f56f6a32ae42
Autor:
Sandra Blanco, Agata Kurowski, Jennifer Nichols, Fiona M Watt, Salvador Aznar Benitah, Michaela Frye
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002403 (2011)
Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can regulate this process is unknown. Here, we identify that an RNA methyltransferase (Misu/Nsun2) is
Externí odkaz:
https://doaj.org/article/3f09e8b8c1c54a4dbd5553c1cc99f2f5
Autor:
Kisa Sung, Agata Kurowski, Carisse Lansiquot, Kanny K. Wan, Samarjit Patnaik, Martin J. Walsh, Michael B. Lazarus
Publikováno v:
ACS Chem Biol
Autophagy is a conserved metabolic pathway that is central to many diseases. Recently, there has been a lot of interest in targeting autophagy with small molecule inhibitors as a possible therapeutic strategy. However, many of the compounds used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6bf5deb72f932d64b4e3a2c50c73af
https://doi.org/10.1021/acschembio.2c00710
https://doi.org/10.1021/acschembio.2c00710
Autor:
Agata Kurowski, Elena Corujo-Simon, Stanley E. Strawbridge, Jennifer Nichols, Alexander G. Fletcher
A crucial aspect of embryology is relating the position of individual cells to the broader geometry of the embryo. A classic example of this is the first cell-fate decision of the mouse embryo, where interior cells become inner cell mass and exterior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f01cb6cbc33e99b27456c170bcb5183
https://doi.org/10.1101/2021.11.15.468285
https://doi.org/10.1101/2021.11.15.468285
Autor:
Lawrence E. Bates, Jennifer Nichols, José C. R. Silva, Thorsten Boroviak, Giuliano Giuseppe Stirparo, Siarhei Hladkou, Agata Kurowski, Hannah T. Stuart, Stanley E. Strawbridge, Ayaka Yanagida
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We used single-cell whole-genome transcriptional profiling and protein quantification to investigate the role of OCT4 in establishing pluripotency in the murine embryo. Surprisingly, most pluripotency-associated factors are induced norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43e422ba3658d70d42d43bde35188c7
https://doi.org/10.1073/pnas.2008890118
https://doi.org/10.1073/pnas.2008890118
FGF signaling plays important roles in many aspects of mammalian development. Fgfr1(−/−) and Fgfr1(−/−) Fgfr2(−/−) mouse embryos on a 129S4 co-isogenic background fail to survive past the peri-implantation stage, whereas Fgfr2(−/−) em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60ec3d37ce411ed17e37ef455fedc26
https://europepmc.org/articles/PMC6370302/
https://europepmc.org/articles/PMC6370302/
Autor:
Elisabete Nascimento, Agata Kurowski, Michaeala Frye, Astrid Gillich, Ilaria Dragoni, Peter Humphreys, Sandra Blanco Benavente, Shobbir Hussain
Publikováno v:
The Journal of Cell Biology
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3896a26894a956a1c23f2670155789
http://europepmc.org/articles/PMC2712989
http://europepmc.org/articles/PMC2712989
Publikováno v:
Human genetics. 130(2)
In mammals, one of the two X chromosomes in female cells is transcriptionally silenced for dosage compensation between the sexes. Chromosome-wide silencing is initiated by the non-coding Xist RNA that accumulates within the inactive X chromosome terr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839e60f091845710189cd44c930f4707
https://pubmed.ncbi.nlm.nih.gov/21567178
https://pubmed.ncbi.nlm.nih.gov/21567178
Autor:
Agata Kurowski, Sandra Blanco, Michaela Frye, Jennifer Nichols, Fiona M. Watt, Salvador Aznar Benitah
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 12, p e1002403 (2011)
PLoS Genetics, Vol 7, Iss 12, p e1002403 (2011)
Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can regulate this process is unknown. Here, we identify that an RNA methyltransferase (Misu/Nsun2) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c698201925ab1fa980caac50cffbc99a
https://doi.org/10.1371/journal.pgen.1002403
https://doi.org/10.1371/journal.pgen.1002403