Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Agata Hogendorf"'
Autor:
Agata Hogendorf, Adam S. Hogendorf, Rafał Kurczab, Grzegorz Satała, Bernadeta Szewczyk, Paulina Cieślik, Gniewomir Latacz, Jadwiga Handzlik, Tomasz Lenda, Katarzyna Kaczorowska, Jakub Staroń, Ryszard Bugno, Beata Duszyńska, Andrzej J. Bojarski
Publikováno v:
Molecules, Vol 26, Iss 15, p 4605 (2021)
A series of N-skatyltryptamines was synthesized and their affinities for serotonin and dopamine receptors were determined. Compounds exhibited activity toward 5-HT1A, 5-HT2A, 5-HT6, and D2 receptors. Substitution patterns resulting in affinity/activi
Externí odkaz:
https://doaj.org/article/161dfe1128284230be1a6f666c15721d
Autor:
Adam S. Hogendorf, Agata Hogendorf, Rafał Kurczab, Grzegorz Satała, Tomasz Lenda, Maria Walczak, Gniewomir Latacz, Jadwiga Handzlik, Katarzyna Kieć-Kononowicz, Joanna M. Wierońska, Monika Woźniak, Paulina Cieślik, Ryszard Bugno, Jakub Staroń, Andrzej J. Bojarski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract A series of 5-aryl-1-alkylimidazole derivatives was synthesized using the van Leusen multicomponent reaction. The chemotype is the first example of low-basicity scaffolds exhibiting high affinity for 5-HT7 receptor together with agonist func
Externí odkaz:
https://doaj.org/article/b2815ce3d4e34da783160c0d85d688cb
Autor:
Katarzyna Kaczorowska, Anna Stankiewicz, Ryszard Bugno, Maria H. Paluchowska, Grzegorz Burnat, Piotr Brański, Paulina Cieślik, Joanna M. Wierońska, Mariusz Milik, Mateusz Nowak, Agnieszka Przybyłowicz, Aneta Kozioł, Agata Hogendorf, Adam S. Hogendorf, Justyna Kalinowska-Tłuścik, Beata Duszyńska, Andrzej Pilc, Andrzej J. Bojarski
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 1981
Volume 24
Issue 3
Pages: 1981
Following the glutamatergic theory of schizophrenia and based on our previous study regarding the antipsychotic-like activity of mGlu7 NAMs, we synthesized a new compound library containing 103 members, which were examined for NAM mGlu7 activity in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bd1032ea689e28fb5b194b8c741a12
https://doi.org/10.3390/ijms24031981
https://doi.org/10.3390/ijms24031981
Autor:
Gitte M. Knudsen, Adam S. Hogendorf, Agata Hogendorf, Ida Nyman Petersen, Andreas Kjaer, Mengfei Xiong, Tomas Ohlsson, Andrzej J. Bojarski, Maria Erlandsson, Matthias M. Herth, Jesper L. Kristensen, Elina T. L’Estrade
Publikováno v:
Capital Region of Denmark
AGH-44 is described as a selective low-basicity serotonin 7 receptor (5-HT7R) agonist. In this paper, we evaluate if AGH-44 can act as a lead structure to develop a 5-HT7R selective positron emission tomography (PET) tracer. 11C-labeling of AGH-44 su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13001465fc2b01be553bb4af69f9b59
https://doi.org/10.1007/s10967-019-06687-3
https://doi.org/10.1007/s10967-019-06687-3
Autor:
Jakub, Staroń, Ryszard, Bugno, Wojciech, Pietruś, Grzegorz, Satała, Stefan, Mordalski, Dawid, Warszycki, Agata, Hogendorf, Adam S, Hogendorf, Justyna, Kalinowska-Tłuścik, Tomasz, Lenda, Bogusław, Pilarski, Andrzej J, Bojarski
Publikováno v:
European journal of medicinal chemistry. 209
Among all of the monoaminergic receptors, the 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6b115ec002170e3812039fd9e3cda87
https://pubmed.ncbi.nlm.nih.gov/33328102
https://pubmed.ncbi.nlm.nih.gov/33328102
Autor:
Dawid Warszycki, Ryszard Bugno, Agata Hogendorf, Rafał Kurczab, Beata Duszyńska, Adam S. Hogendorf, Andrzej J. Bojarski, Wojciech Pietruś, Tomasz Lenda, Jakub Staroń, Grzegorz Satała, Anna Wantuch
Publikováno v:
European Journal of Medicinal Chemistry. 220:113533
The selective serotonin reuptake inhibitors (SSRIs), acting at the serotonin transporter (SERT), are one of the most widely prescribed antidepressant medications. All five approved SSRIs possess either fluorine or chlorine atoms, and there is a limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92afc552b4b8acf7ae6d6795197acdc8
https://doi.org/10.1016/j.ejmech.2021.113533
https://doi.org/10.1016/j.ejmech.2021.113533
Autor:
Jakub, Staroń, Rafał, Kurczab, Dawid, Warszycki, Grzegorz, Satała, Martyna, Krawczyk, Ryszard, Bugno, Tomasz, Lenda, Piotr, Popik, Adam S, Hogendorf, Agata, Hogendorf, Krzysztof, Dubiel, Mikołaj, Matłoka, Rafał, Moszczyński-Pętkowski, Jerzy, Pieczykolan, Maciej, Wieczorek, Paweł, Zajdel, Andrzej J, Bojarski
Publikováno v:
European journal of medicinal chemistry. 185
A virtual screening campaign aimed at finding structurally new compounds active at 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c6f441de5ac448bba60dad3749467a9
https://pubmed.ncbi.nlm.nih.gov/31734022
https://pubmed.ncbi.nlm.nih.gov/31734022
Autor:
Adam S, Hogendorf, Agata, Hogendorf, Katarzyna, Popiołek-Barczyk, Agata, Ciechanowska, Joanna, Mika, Grzegorz, Satała, Maria, Walczak, Gniewomir, Latacz, Jadwiga, Handzlik, Katarzyna, Kieć-Kononowicz, Evgeni, Ponimaskin, Sophie, Schade, Andre, Zeug, Monika, Bijata, Maciej, Kubicki, Rafał, Kurczab, Tomasz, Lenda, Jakub, Staroń, Ryszard, Bugno, Beata, Duszyńska, Bogusław, Pilarski, Andrzej J, Bojarski
Publikováno v:
European journal of medicinal chemistry. 170
The 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de880324ed0c9f75ff084d546607fd39
https://pubmed.ncbi.nlm.nih.gov/30904783
https://pubmed.ncbi.nlm.nih.gov/30904783
Autor:
Monika Bijata, Ryszard Bugno, Maciej Kubicki, Andrzej J. Bojarski, Joanna Mika, Beata Duszyńska, Jadwiga Handzlik, Adam S. Hogendorf, Katarzyna Kieć-Kononowicz, Jakub Staroń, Evgeni Ponimaskin, Agata Hogendorf, Maria Walczak, Gniewomir Latacz, Bogusław Pilarski, Tomasz Lenda, Rafał Kurczab, Sophie Kristin Schade, Agata Ciechanowska, Grzegorz Satała, Katarzyna Popiolek-Barczyk, Andre Zeug
The 5-HT7 receptor has recently gained much attention due to its involvement in multiple physiological functions and diseases. The insufficient quality of the available molecular probes prompted design of fluorinated 3-(1-alkyl-1H-imidazol-5-yl)-1H-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27df185f4609682059c28c0c7fae812
https://ruj.uj.edu.pl/xmlui/handle/item/98116
https://ruj.uj.edu.pl/xmlui/handle/item/98116
Autor:
Wojciech Pietruś, Andrzej J. Bojarski, Adam S. Hogendorf, Justyna Kalinowska-Tłuścik, Agata Hogendorf, Stefan Mordalski, Bogusław Pilarski, Dawid Warszycki, Ryszard Bugno, Grzegorz Satała, Jakub Staroń, Tomasz Lenda
Publikováno v:
European Journal of Medicinal Chemistry. 209:112916
Among all of the monoaminergic receptors, the 5-HT6R has the highest number of non-basic ligands (approximately 5% of compounds stored in 25th version of ChEMBL database have the strongest basic pKa below 5, calculated using the Instant JChem calcula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6989a1d578c2ed4067c91a15cb67282
https://doi.org/10.1016/j.ejmech.2020.112916
https://doi.org/10.1016/j.ejmech.2020.112916