Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Agata Golaszewska"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Adrenaline is believed to play a role in thrombosis and hemostasis. The complex effect of its clinically relevant concentrations on thrombus formation, coagulation and fibrinolysis in human blood has never been specifically studied.Method
Externí odkaz:
https://doaj.org/article/efcdd7a6556e480a8680055871f354b1
Autor:
Tomasz Misztal, Agata Golaszewska, Natalia Marcińczyk, Maria Tomasiak-Łozowska, Małgorzata Szymanowska, Ewa Chabielska, Tomasz Rusak
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 779 (2022)
During pathogen invasion, activated neutrophils secrete myeloperoxidase (MPO), which generates high local concentrations of hypochlorous acid (HOCl), a strong antimicrobial agent. Prolonged or uncontrolled HOCl production may, however, affect hemosta
Externí odkaz:
https://doaj.org/article/8e4c2afcf0b2454fb2a085d81a9bc480
Autor:
Tomasz Misztal, Agata Golaszewska, Justyna Branska-Januszewska, Natalia Marcinczyk, Ewa Chabielska, Marian Tomasiak, Tomasz Rusak
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Background: Recent studies indicate that aquaporin (AQP) water channels have a regulatory function in human platelet secretion and in procoagulant response of murine platelets. However, the engagement of AQPs in morphological changes, procoagulant re
Externí odkaz:
https://doaj.org/article/58294802ff9a4d66b79a27b1bd2c8de4
Autor:
Ewa Chabielska, M. M. Tomasiak-Lozowska, Agata Golaszewska, Tomasz Rusak, Marta Iwanicka, Agnieszka Leszczynska, Natalia Marcinczyk, Tomasz Misztal
Publikováno v:
Free Radical Biology and Medicine. 141:426-437
Hypochlorite (HOCl), a strong oxidant and antimicrobial agent, has been proposed to be associated with hemostatic abnormalities during inflammatory response. However, its complex impact on hemostasis is not completely understood. In this report we st
Autor:
Agata Golaszewska
Publikováno v:
Acta Haematologica Polonica. 50:65-73
StreszczenieZakrzepy i zatory stanowią obecnie główną bezpośrednią przyczynę zgonów u hospitalizowanych pacjentów w krajach rozwiniętych. Szczególnie istotną rolę w procesie krzepnięcia, jak również w stanach patologicznej nadkrzepliw
Autor:
Ewa Chabielska, Natalia Marcinczyk, Tomasz Misztal, Irena Kasacka, Agata Golaszewska, Anna Gromotowicz-Poplawska, Jakub Strawa, Michał Tomczyk
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
In our previous study, we showed that ellagitannin- and procyanidin-rich tormentil extract (TE) decreased experimental arterial thrombosis in normoglycemic rats through platelet inhibition. TE also slightly increased coagulation and attenuated fibrin
Autor:
Ewa Chabielska, Marian Tomasiak, Agata Golaszewska, Justyna Brańska-Januszewska, Natalia Marcinczyk, Tomasz Misztal, Tomasz Rusak
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
Background: Recent studies indicate that aquaporin (AQP) water channels have a regulatory function in human platelet secretion and in procoagulant response of murine platelets. However, the engagement of AQPs in morphological changes, procoagulant re
Autor:
Natalia Marcinczyk, Tomasz Misztal, Agata Golaszewska, Tomasz Rusak, Ewa Chabielska, Anna Gromotowicz-Poplawska
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 393(4)
The goal of the study was the assessment of heterogeneous platelet activation status in thrombus. In a ferric(III) chloride (FeCl3) thrombosis (intravital) model of C57BL/6 J mice, the area of irreversibly activated (phosphatidylserine (PS)-positive)
Autor:
Tomasz Rusak, Ewa Chabielska, Natalia Marcinczyk, Tomasz Misztal, Agata Golaszewska, Aleksiejczuk M, Anna Gromotowicz-Poplawska
Publikováno v:
Vascular pharmacology.
An increase in aldosterone levels positively correlates with an increased risk of acute cardiovascular thrombotic events. The aim of the study was to determine the mechanism of action of prothrombotic aldosterone focusing on the rapid effects of the
Autor:
Tomasz Rusak, Marta Bruczko, Beata Szynaka, Marta Gąsowska, Agata Golaszewska, Justyna Brańska-Januszewska, Tomasz Misztal, Marian Tomasiak
Publikováno v:
Acta biochimica Polonica. 65(4)
This study was undertaken to establish the presence and the role of aquaporins (AQPs) in human platelets. Immunodetection with polyclonal antibodies and fluorescent microscopy suggest the presence of AQP isoforms – 0–7 and 9–12 – localized (i