Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Agata Charzyńska"'
Autor:
Maciej Jaśkiewicz, Adrianna Moszyńska, Jarosław Króliczewski, Aleksandra Cabaj, Sylwia Bartoszewska, Agata Charzyńska, Magda Gebert, Michał Dąbrowski, James F. Collawn, Rafal Bartoszewski
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-19 (2022)
Abstract The hypoxia-inducible factors (HIF) are transcription factors that activate the adaptive hypoxic response when oxygen levels are low. The HIF transcriptional program increases oxygen delivery by inducing angiogenesis and by promoting metabol
Externí odkaz:
https://doaj.org/article/75c92cbadd1f4810a08902d147f250fb
Autor:
Magdalena Wolczyk, Remigiusz Serwa, Agata Kominek, Agata Klejman, Jacek Milek, Marta Chwałek, Laura Turos-Korgul, Agata Charzyńska, Michal Dabrowski, Magdalena Dziembowska, Tomasz Skorski, Katarzyna Piwocka, Paulina Podszywalow-Bartnicka
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106543- (2023)
Summary: Chronic myeloid leukemia (CML) cells circulate between blood and bone marrow niche, representing different microenvironments. We studied the role of the two RNA-binding proteins, T-cell-restricted intracellular antigen (TIAR), and the fragil
Externí odkaz:
https://doaj.org/article/8fb50f9b7118469f8c9c75687dad3cc8
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background A vast amount of microarray data on transcriptomic response to injury has been collected so far. We designed the analysis in order to identify the genes displaying significant changes in expression after wounding in different orga
Externí odkaz:
https://doaj.org/article/1cc6501db408463ebae23355f4d5402d
Autor:
Agata Charzyńska, Anna Gambin
Publikováno v:
Entropy, Vol 18, Iss 1, p 13 (2015)
In this paper, we investigate efficient estimation of differential entropy for multivariate random variables. We propose bias correction for the nearest neighbor estimator, which yields more accurate results in higher dimensions. In order to demonstr
Externí odkaz:
https://doaj.org/article/b264f59c93a0488ab18170e9320b6b98
Autor:
Aleksandra Gawryluk, Anita Cybulska-Klosowicz, Agata Charzynska, Renata Zakrzewska, Alicja Sobolewska, Malgorzata Kossut, Monika Liguz-Lecznar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Aging-related biochemical changes in nerve cells lead to dysfunctional synapses and disrupted neuronal circuits, ultimately affecting vital processes such as brain plasticity, learning, and memory. The imbalance between excitation and inhibi
Externí odkaz:
https://doaj.org/article/7b8334e2e3094540ae43bd097a139f26
Autor:
Kamil Grycz, Anna Głowacka, Benjun Ji, Kamila Krzywdzińska, Agata Charzyńska, Julita Czarkowska-Bauch, Olga Gajewska-Woźniak, Małgorzata Skup
Publikováno v:
Experimental Neurology. 354:114098
Chondroitin sulfate proteoglycans (CSPGs) consist of core proteins and glycosaminoglycan side chains. Tenascins, and hyaluronan and proteoglycan link protein 1 (HAPLN), link CSPGs with a hyaluronan backbone to constitute perineuronal nets (PNNs), whi
Publikováno v:
Cellular Signalling. 90:110209
We analyzed the effects of selective knockdown of either HIF-1α or HIF-2α on the transcriptional response to hypoxia of human umbilical endothelial cells at two time-points (2 h and 8 h) of hypoxia. We focused on 13 previously identified hypoxia-re
Publikováno v:
BioTechnologia. 3:291-308
Publikováno v:
BMC Systems Biology
Background As suggested by the origin of the word, sphingolipids are mysterious molecules with various roles in antagonistic cellular processes such as autophagy, apoptosis, proliferation and differentiation. Moreover, sphingolipids have recently bee
Publikováno v:
JAK-STAT
Despite a conceptually simple mechanism of signaling, the JAK-STAT pathway exhibits considerable behavioral complexity. Computational pathway models are tools to investigate in detail signaling process. They integrate well with experimental studies,