Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Agata, Paneth"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Nowadays, dermatophyte infections are relatively easy to cure, especially since the introduction of orally administered antifungals such as terbinafine and itraconazole. However, these drugs may cause side effects due to liver damage or thei
Externí odkaz:
https://doaj.org/article/970893d52b834388ae183c99a822b55f
Autor:
Lidia Węglińska, Adrian Bekier, Nazar Trotsko, Barbara Kaproń, Tomasz Plech, Katarzyna Dzitko, Agata Paneth
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2621-2634 (2022)
A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and sulfadiazine (SDZ). We previously reported on the identification of the com
Externí odkaz:
https://doaj.org/article/79d58e45c8734949b193085685825372
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17521 (2023)
The number of people affected by cancer and antibiotic-resistant bacterial infections has increased, such that both diseases are already seen as current and future leading causes of death globally. To address this issue, based on a combined in silico
Externí odkaz:
https://doaj.org/article/b5361b31f67646ae881e1f40686da6b7
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Confinement can result in unusual properties leading to new, exciting discoveries in the nano-realm. One such consequence of confinement at the nanoscale is extremally large isotopic fractionation, especially at sub-van der Waals distances.
Externí odkaz:
https://doaj.org/article/e057500f47c1413da079e3c3fad7bfaf
Publikováno v:
Molecules, Vol 28, Iss 13, p 5287 (2023)
The main aim of the current project was to investigate the effect of the linker size in 4-alkyl-5-aryl-1,2,4-triazole-3-thione derivatives, known as a group of antiepileptic drug candidates, on their affinity towards voltage-gated sodium channels (VG
Externí odkaz:
https://doaj.org/article/22bde85ae03d40b68e61b26d9ee565ca
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1145-1164 (2021)
We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at N1 position, on highly virulent RH strain of Toxoplasma gondii. Among them, the highest in vitro anti-Toxoplasma activity was found with the
Externí odkaz:
https://doaj.org/article/c469cec21766439e99c28e34fbdb3bfc
Autor:
Katarzyna Dzitko, Barbara Kaproń, Agata Paneth, Adrian Bekier, Tomasz Plech, Piotr Paneth, Nazar Trotsko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2069 (2023)
Two distinct intracellular pathogens, namely Mycobacterium tuberculosis (Mtb) and Toxoplasma gondii (Tg), cause major public health problems worldwide. In addition, serious and challenging health problems of co-infections of Tg with Mtb have been rec
Externí odkaz:
https://doaj.org/article/0e7149ec297147a2ba204552ac8e7e75
Autor:
Agnieszka Krzemińska, José-Emilio Sánchez-Aparicio, Jean-Didier Maréchal, Agata Paneth, Piotr Paneth
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7705 (2022)
Disaccharide complexes have been shown experimentally to be useful for drug delivery or as an antifouling surface biofilm, and are promising drug-encapsulation and delivery candidates. Although such complexes are intended for medical applications, to
Externí odkaz:
https://doaj.org/article/03bf65efbdf84322abbaffa5969dcb3b
Publikováno v:
The Journal of Physical Chemistry Letters. 14:3735-3742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac1a038d3d7ff3c8d6b476d886b1683c
https://doi.org/10.1021/acs.jpclett.3c00610
https://doi.org/10.1021/acs.jpclett.3c00610
Autor:
Monika Rola, Jakub Krassowski, Julita Górska, Anna Grobelna, Wojciech Płonka, Agata Paneth, Piotr Paneth
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256834 (2021)
The current pandemic outbreak clearly indicated the urgent need for tools allowing fast predictions of bioactivity of a large number of compounds, either available or at least synthesizable. In the computational chemistry toolbox, several such tools
Externí odkaz:
https://doaj.org/article/46b2edb30ec148f6b53976bcf1873f07