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Role of I182, R187, and K188 Amino Acid Residues in the Catalytic Domain of HIV-1 Integrase in the Processes of Reverse Transcription and Integration.

Autor: Kikhai TF; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia. kih.t1996@yandex.ru., Agapkina YY; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia., Prikazchikova TA; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia., Vdovina MV; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia., Shekhtman SP; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia., Fomicheva SV; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119991, Russia., Korolev SP; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia., Gottikh MB; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia. gottikh@belozersky.msu.ru.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia.

Publikováno v: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2024 Mar; Vol. 89 (3), pp. 462-473.

DNA sequence-specific ligands. XVIII. Synthesis, physico-chemical properties; genetic, virological, and biochemical studies of fluorescent dimeric bisbenzimidazoles DBPA(n).

Autor: Koval VS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia., Arutyunyan AF; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia., Salyanov VI; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia., Kostyukov AA; Emanuel Institute of Biochemical Physics, RAS, Moscow 119334, Russia., Melkina OE; Scientific Center 'Kurchatov Institute', Research Institute of Genetics & Selection of Industrial Microorganisms, Moscow 117545, Russia., Zavilgelsky GB; Scientific Center 'Kurchatov Institute', Research Institute of Genetics & Selection of Industrial Microorganisms, Moscow 117545, Russia., Klimova RR; Ivanovsky Institute of Virology, Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow 123098, Russia., Kushch AA; Ivanovsky Institute of Virology, Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow 123098, Russia., Korolev SP; Department of Chemistry and Belozersky Institute of Physicochemical Biology, Moscow State University, Moscow 119991, Russia., Agapkina YY; Department of Chemistry and Belozersky Institute of Physicochemical Biology, Moscow State University, Moscow 119991, Russia., Gottikh MB; Department of Chemistry and Belozersky Institute of Physicochemical Biology, Moscow State University, Moscow 119991, Russia., Vaiman AV; Institute of Carcinogenesis, FSBI 'N.N. Blokhin National Medical Research Center of Oncology', The Ministry of Health of the Russian Federation, 115478 Moscow, Russia., Rybalkina EY; Institute of Carcinogenesis, FSBI 'N.N. Blokhin National Medical Research Center of Oncology', The Ministry of Health of the Russian Federation, 115478 Moscow, Russia., Susova OY; Institute of Carcinogenesis, FSBI 'N.N. Blokhin National Medical Research Center of Oncology', The Ministry of Health of the Russian Federation, 115478 Moscow, Russia., Zhuze AL; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia. Electronic address: zhuze@eimb.ru.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Apr 01; Vol. 28 (7), pp. 115378. Date of Electronic Publication: 2020 Feb 13.

[Nitrobenzofuroxane derivatives as dual action hiv-1 inhibitors].

Autor: Korolev SP; Belozeksky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia., Pustovarova MA; Belozeksky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia., Starosotnikov AM; Zelinsky Institute of Organic Chemistry, Moscow, Russia., Bastrakov MA; Zelinsky Institute of Organic Chemistry, Moscow, Russia., Agapkina YY; Belozeksky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia., Shevelev SA; Zelinsky Institute of Organic Chemistry, Moscow, Russia., Gottikh MB; Belozeksky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.

Publikováno v: Biomeditsinskaia khimiia [Biomed Khim] 2016 Nov; Vol. 62 (6), pp. 725-728.

Structural-Functional Analysis of 2,1,3-Benzoxadiazoles and Their N-oxides As HIV-1 Integrase Inhibitors.

Autor: Korolev SP; Department of Chemistry, Lomonosov Moscow State University, Leninskie gory, 1/3, Moscow, Russia, 119991 ; Belozersky Research Institute of Physicochemical Biology, Lomonosov Moscow State University, Leniskie gory, 1/40, Moscow, Russia, 119991., Kondrashina OV, Druzhilovsky DS, Starosotnikov AM, Dutov MD, Bastrakov MA, Dalinger IL, Filimonov DA, Shevelev SA, Poroikov VV, Agapkina YY, Gottikh MB

Publikováno v: Acta naturae [Acta Naturae] 2013 Jan; Vol. 5 (1), pp. 63-72.