Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Agapios Sachinidis"'
Autor:
Anna Papazoglou, Christina Henseler, Sandra Weickhardt, Johanna Daubner, Teresa Schiffer, Karl Broich, Jürgen Hescheler, Agapios Sachinidis, Dan Ehninger, Britta Haenisch, Marco Weiergräber
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract Objectives The G72 mouse model of schizophrenia represents a well-known model that was generated to meet the main translational criteria of isomorphism, homology and predictability of schizophrenia to a maximum extent. In order to get a more
Externí odkaz:
https://doaj.org/article/7f1c175c736b4397a2258988dcbde63e
Autor:
Anna Cherianidou, Franziska Kappenberg, Florian Seidel, Aviseka Acharya, Panagiota Papazoglou, Sureshkumar Perumal Srinivasan, Jürgen Hescheler, Luying Peng, Marcel Leist, Jan G. Hengstler, Jörg Rahnenführer, Agapios Sachinidis
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Summary Animal studies for embryotoxicity evaluation of potential therapeutics and environmental factors are complex, costly, and time-consuming. Often, studies are not of human relevance because of species differences. In the present study, we recap
Externí odkaz:
https://doaj.org/article/3033166cf6ba47248dc4369924655b7f
Autor:
Anna Papazoglou, Christina Henseler, Sandra Weickhardt, Jenni Teipelke, Panagiota Papazoglou, Johanna Daubner, Teresa Schiffer, Damian Krings, Karl Broich, Jürgen Hescheler, Agapios Sachinidis, Dan Ehninger, Catharina Scholl, Britta Haenisch, Marco Weiergräber
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296959 (2024)
A variety of Alzheimer's disease (AD) mouse models has been established and characterized within the last decades. To get an integrative view of the sophisticated etiopathogenesis of AD, whole genome transcriptome studies turned out to be indispensab
Externí odkaz:
https://doaj.org/article/8f0be2875056487596f407826a004946
Autor:
Anna Papazoglou, Christina Henseler, Sandra Weickhardt, Johanna Daubner, Teresa Schiffer, Karl Broich, Jürgen Hescheler, Dan Ehninger, Catharina Scholl, Britta Haenisch, Agapios Sachinidis, Marco Weiergräber
Publikováno v:
Data in Brief, Vol 50, Iss , Pp 109594- (2023)
A variety of Alzheimer disease (AD) mouse models has been established and characterized within the last decades. These models are generated to meet the principal criteria of AD isomorphism, homology and predictability to a maximum extent. To get an i
Externí odkaz:
https://doaj.org/article/57ee709afb83440598afc2d1a48c1970
Autor:
Sureshkumar Perumal Srinivasan, Harshal Nemade, Anna Cherianidou, Luying Peng, Sara Cruz-Molina, Alvaro Rada-Iglesias, Agapios Sachinidis
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Significant evidence points to Strip2 being a key regulator of the differentiation processes of pluripotent embryonic stem cells. However, Strip2 mediated epigenetic regulation of embryonic differentiation and development is quite unknown. H
Externí odkaz:
https://doaj.org/article/315833faca3e4cbe99743caac93a8564
Autor:
Sarkawt Hamad, Daniel Derichsweiler, John Antonydas Gaspar, Konrad Brockmeier, Jürgen Hescheler, Agapios Sachinidis, Kurt Paul Pfannkuche
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Introduction Endothelial cells (ECs) form the inner lining of all blood vessels of the body play important roles in vascular tone regulation, hormone secretion, anticoagulation, regulation of blood cell adhesion and immune cell extravasation
Externí odkaz:
https://doaj.org/article/1e160f6c5ed2454b8d053c9df50c2f23
Autor:
Aviseka Acharya, Harshal Nemade, Symeon Papadopoulos, Jürgen Hescheler, Felix Neumaier, Toni Schneider, Krishna Rajendra Prasad, Khadija Khan, Ruth Hemmersbach, Eduardo Gade Gusmao, Athanasia Mizi, Argyris Papantonis, Agapios Sachinidis
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104577- (2022)
Summary: Exposure to outer space microgravity poses a risk for the development of various pathologies including cardiovascular disease. To study this, we derived cardiomyocytes (CMs) from human-induced pluripotent stem cells and exposed them to simul
Externí odkaz:
https://doaj.org/article/acd50b3c8aed4221863fb010c5cda349
Autor:
Gabriel Peinkofer, Martina Maass, Kurt Pfannkuche, Agapios Sachinidis, Stephan Baldus, Jürgen Hescheler, Tomo Saric, Marcel Halbach
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) are regarded as promising cell type for cardiac cell replacement therapy, but it is not known whether the developmental stage influences their persistence and function
Externí odkaz:
https://doaj.org/article/d6005aa359f9412ead98d7b324bd620d
Autor:
Muhammad Imran Arshaad, Magdalena Elisabeth Siwek, Christina Henseler, Johanna Daubner, Dan Ehninger, Jürgen Hescheler, Agapios Sachinidis, Karl Broich, Anna Papazoglou, Marco Weiergräber
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract T-type Ca2+ channels are assumed to contribute to hippocampal theta oscillations. We used implantable video-EEG radiotelemetry and qPCR to unravel the role of Cav3.2 Ca2+ channels in hippocampal theta genesis. Frequency analysis of spontaneo
Externí odkaz:
https://doaj.org/article/1e4f22c7d6c44f4a915de426ed9b8a9a
Autor:
Florian Seidel, Anna Cherianidou, Franziska Kappenberg, Miriam Marta, Nadine Dreser, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Tamara Rotshteyn, Andreas Scholtz-Illigens, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sachinidis, Jan Georg Hengstler
Publikováno v:
Cells, Vol 11, Iss 21, p 3404 (2022)
Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a r
Externí odkaz:
https://doaj.org/article/1c72b068b68a48ac9b8dc05a0289a26b