Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Agam R. Sheth"'
Autor:
Agam R. Sheth, David J.W. Grant
Publikováno v:
KONA Powder and Particle Journal, Vol 23, Iss 0, Pp 36-48 (2014)
The majority of drug products are solid dosage forms, most of which contain the drug substance in the crystalline state. This review considers the forces responsible for crystal packing, the various types of pharmaceutical crystals, and the methods u
Externí odkaz:
https://doaj.org/article/61dc178e10c84813957b5eba93ba3b3e
Publikováno v:
Journal of Pharmaceutical Sciences. 99:4973-4981
(1S,5R)-2-{[(4S)-azepan-4-ylamino]carbonyl}-7-oxo-2,6-diazabicyclo[3.2.0] heptane-6-sulfonic acid (Compound 1) is a β-lactamase inhibitor for intravenous administration. The objective of this preformulation study was to determine the most appropriat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cddc19a077622781e6f518d88024974
https://doi.org/10.1002/jps.22225
https://doi.org/10.1002/jps.22225
Publikováno v:
Crystal Growth & Design. 6:1318-1323
Monte Carlo simulations in the isotension−isothermal and Gibbs ensembles were carried out to investigate the structural properties of warfarin sodium 2-propanol and the ability of this compound to retain 2-propanol as a function of vapor pressure a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0eb2ea942e9ac643481247e5e842d2
https://doi.org/10.1021/cg050542y
https://doi.org/10.1021/cg050542y
Publikováno v:
Journal of the American Chemical Society. 127:6641-6651
Structural and solid-state changes of piroxicam in its crystalline form under mechanical stress were investigated using cryogenic grinding, powder X-ray diffractometry, diffuse-reflectance solid-state ultraviolet-visible spectroscopy, variable-temper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b1f87d1cdbe3177360e0a7d8f537b1
https://doi.org/10.1021/ja045823t
https://doi.org/10.1021/ja045823t
Publikováno v:
Journal of Pharmaceutical Sciences. 93:3013-3026
The dehydration kinetics of piroxicam monohydrate ( PM ) is analyzed by both model‐free and model‐fitting approaches. The conventional model‐fitting approach assuming a fixed mechanism throughout the reaction is found to be too simplistic. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cf2cfa2c1a4fbe471418d099c96bac
https://doi.org/10.1002/jps.20191
https://doi.org/10.1002/jps.20191
Publikováno v:
Crystal Growth & Design. 5:571-578
The local structures of amorphous phases of piroxicam were studied to explain differences in their recrystallization behavior, which we reported earlier (Sheth, A. R.; Bates, S.; Muller, F. X.; Grant, D. J. W. Polymorphism in piroxicam. Cryst. Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678b4400f08cf478a59e21529b133b29
https://doi.org/10.1021/cg049757i
https://doi.org/10.1021/cg049757i
Publikováno v:
Journal of Pharmaceutical Sciences. 93:2669-2680
The goal of the present work was to understand the effect of relative humidity (RH) and temperature on the molecular structure, crystal structure, and physical properties of warfarin sodium 2-propanol solvate (W). After previous determination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc537744b72b3e92d579784110eb645b
https://doi.org/10.1002/jps.20164
https://doi.org/10.1002/jps.20164
Autor:
Victor G. Young, David J.W. Grant, Neil R. Brooks, Agam R. Sheth, Toshihito Hosokawa, Sharmistha Datta
Publikováno v:
Crystal Growth & Design. 4:1195-1201
This work describes the crystal structures of phenylbutazone 2:1 solvates with benzene, cyclohexane, 1,4-dioxane, tetrahydrofuran, tetrachloromethane, and chloroform. These solvates are isostructural, with the exception of the chloroform solvate. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba255affa407286a8ad4e3da57bcefd7
https://doi.org/10.1021/cg049923m
https://doi.org/10.1021/cg049923m
Publikováno v:
Crystal Growth & Design. 4:1091-1098
Piroxciam is a polymorphic drug. However, reports on the number and nomenclature of the polymorphs of piroxicam and the complete hydrogen-bonding patterns of piroxicam molecules in the crystal forms are in conflict and are sources of confusion, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646b708eef50518865afd80ca9d47cd6
https://doi.org/10.1021/cg049876y
https://doi.org/10.1021/cg049876y
Autor:
Agam R. Sheth, Eric J. Munson, Zedong Dong, Indra Prakash, Victor G. Young, David J.W. Grant, Steve A. Schroeder
Publikováno v:
Pharmaceutical Research. 19:1549-1553
Purpose. To determine the crystal structure of the neotame anhydrate polymorph G and to evaluate X-ray powder diffractometry (XRPD) with molecular modeling as an alternative method for determining the crystal structure of this conformationally flexib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9fd493152b26e9006547b8a85413b4
https://doi.org/10.1023/a:1020473103603
https://doi.org/10.1023/a:1020473103603