AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy.

Autor: Dohmen M; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany.; Center for Translational & Clinical Research Aachen (CTC-A), Medical School, RWTH Aachen University, 52074, Aachen, Germany., Krieg S; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany., Agalaridis G; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany.; Miltenyi Biotec GmbH, Friedrich-Ebert-Straße 68, 51429, Bergisch Gladbach, Germany., Zhu X; CARIM School for Cardiovascular Diseases, Maastricht University, P.O. box 616, 6200 MD, Maastricht, The Netherlands., Shehata SN; Nestlé Research, EPFL Innovation Park, 1015, Lausanne, Switzerland., Pfeiffenberger E; Division of Molecular Pathophysiology, Biocenter, Innsbruck Medical University, Innrain 80/82, 6020, Innsbruck, Austria., Amelang J; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany., Bütepage M; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany., Buerova E; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany., Pfaff CM; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany.; AstraZeneca GmbH, Tinsdaler Weg 183, 22880, Wedel, Germany., Chanda D; CARIM School for Cardiovascular Diseases, Maastricht University, P.O. box 616, 6200 MD, Maastricht, The Netherlands., Geley S; Division of Molecular Pathophysiology, Biocenter, Innsbruck Medical University, Innrain 80/82, 6020, Innsbruck, Austria., Preisinger C; Proteomics Facility, Interdisciplinary Center for Clinical Research (IZKF) Aachen, Medical School, RWTH Aachen University, 52074, Aachen, Germany., Sakamoto K; Nestlé Research, EPFL Innovation Park, 1015, Lausanne, Switzerland.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Lüscher B; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany. luescher@rwth-aachen.de., Neumann D; CARIM School for Cardiovascular Diseases, Maastricht University, P.O. box 616, 6200 MD, Maastricht, The Netherlands. d.neumann@maastrichtuniversity.nl.; Department of Pathology, University Medical Center Maastricht, 6229 HX, Maastricht, The Netherlands. d.neumann@maastrichtuniversity.nl., Vervoorts J; Institute of Biochemistry and Molecular Biology, Medical School, RWTH Aachen University, 52074, Aachen, Germany. jvervoorts-weber@ukaachen.de.

Publikováno v: Nature communications [Nat Commun] 2020 Feb 25; Vol. 11 (1), pp. 1032. Date of Electronic Publication: 2020 Feb 25.

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Genetic variation in healthy oldest-old.

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Publikováno v: PloS one [PLoS One] 2009 Aug 14; Vol. 4 (8), pp. e6641. Date of Electronic Publication: 2009 Aug 14.

Discovery of 3-Amino-1 H -pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family.

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Advances in autophagy as a target in the treatment of tumours.

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