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Allergic Reactions to Metamizole: Immediate and Delayed Responses

Autor: Blanca-López N, Pérez-Sánchez N, Agúndez JA, García-Martin E, Torres MJ, Cornejo-García JA, Perkins JR, Miranda MA, Andreu I, Mayorga C, Canto G, Blanca M, Doña I

Publikováno v: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Background: Pyrazolones are the most common causes of selective nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity. We studied a large group of patients with immediate and delayed selective responses to metamizole. Methods: Patients with su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d42762879c407c5049e3ad5706804033
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7767

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Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole

Autor: Ariza A, García-Martín E, Salas M, Montañez MI, Mayorga C, Blanca-Lopez N, Andreu I, Perkins J, Blanca M, Agúndez JA, Torres MJ

Publikováno v: SCIENTIFIC REPORTS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common cause of hypersensitivity reactions, with pyrazolones the most frequent drugs inducing selective reactions. Immediate selective hypersensitivity to pyrazolones is thought to be mediat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7c3e2a18e9f9af2e2374a41a22086017
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7768

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Akademický článek

Sleep Disorders and Sleep Problems in Patients With Tourette Syndrome and Other Tic Disorders: Current Perspectives

Autor: Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Agúndez JAG

Publikováno v: Nature and Science of Sleep, Vol Volume 14, Pp 1313-1331 (2022)

Félix Javier Jiménez-Jiménez,1 Hortensia Alonso-Navarro,1 Elena García-Martín,2 José AG Agúndez2 1Section of Neurology, Hospital Universitario Del Sureste, Arganda del Rey, Madrid, Spain; 2Universidad de Extremadura, University Institute of Mo

Externí odkaz: https://doaj.org/article/a99601d3360d42e3910f60f8d18dfe78

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Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole

Autor: Martínez C, Andreu I, Amo G, Miranda MA, Esguevillas G, Torres MJ, Blanca-López N, Blanca M, García-Martín E, Agúndez JA

Publikováno v: BIOCHEMICAL PHARMACOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Metamizole is a pain-killer drug that has been banned in some countries because of its toxicity, but it is still used in many countries due to its effective analgesic and antispasmodic properties. Although large variability in the biodisposition and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7c14d86539cfa8242ee2e3dbc8e08342
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7795

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Hypersensitivity reactions to non-steroidal anti-inflammatory drugs

Autor: Cornejo-Garcia JA, Blanca-López N, Doña I, Andreu I, Agúndez JA, Carballo M, Blanca M, Canto MG

Publikováno v: CURRENT DRUG METABOLISM
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

NSAIDs are the most important group of drugs involved in hypersensitivity drug reactions, and include heterogeneous compounds with very different chemical structures. These reactions can be IgE dependent (immediate reactions), T cell-mediated (non-im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::38f6256a4e5d580fa25b9510bf92c480
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7779

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