Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Afzal M Dogar"'
Autor:
Afzal M Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D Schmid, Philipp Bucher, Lukas C Kühn
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206823 (2018)
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in m
Externí odkaz:
https://doaj.org/article/d43d4b9a7f234dc59c8770670f14857f
Autor:
J H Beer, Afzal M. Dogar, Luca Liberale, Nicole R. Bonetti, Théo A. Meister, Thomas F. Lüscher, Giovanni G. Camici, Rodrigo Soria, Alexander Akhmedov, Franz H. Messerli, Stefano Ministrini, Urs Scherrer, Emrush Rexhaj
Publikováno v:
International Journal of Cardiology. 343:92-101
Assisted reproductive technologies (ART) induce premature vascular aging in human offspring. The related alterations are well-established risk factors for stroke and predictors of adverse stroke outcome. However, given the young age of the human ART
Publikováno v:
Current molecular pharmacology.
Background: The activity of the amiloride-sensitive epithelial sodium channel (ENaC) in the tight epithelia of the lung is regulated by proteolytic activation and ubiquitination. Pathophysiology of lung diseases is directly related to changes in one
Autor:
Julian A. Zagalak, Harry Towbin, Jonathan Hall, Mirjam Menzi, Florian Wullschleger, Hartmut Jahns, Fabian Schmich, Afzal M. Dogar
Publikováno v:
RNA. 21:2132-2142
Short interfering RNAs (siRNAs) are mediators of RNA interference (RNAi), a commonly used technique for selective down-regulation of target gene expression. Using an equimolar mixture of A, G, C, and U phosphoramidites during solid-phase synthesis, w
Publikováno v:
Nucleic Acid Therapeutics. 24:149-159
Thrombospondin 1 (THBS1) is a secreted protein with a variety of biological functions, including a potent anti-angiogenic activity and activation of latent transforming growth factor beta (TGF-β). In many human cancers it is expressed at low levels,
Autor:
Ludwig Stenz, Stefano F. Rimoldi, Emrush Rexhaj, Théo A. Meister, Urs Scherrer, Ariane Paolini-Giacobino, Claudio Sartori, Rodrigo Soria, Afzal M. Dogar
Publikováno v:
Hypertension. 68
Environmental influences acting early in life predispose to premature cardiovascular disease. In line with this concept, assisted reproductive technologies (ART) cause premature vascular ageing and arterial hypertension in mice and humans, but the un
Autor:
Ramona Pauchard-Batschulat, Christoph D. Schmid, Larry Richman, Barbara Grisoni-Neupert, Otto Hagenbüchle, Philipp Bucher, Alexandra Paillusson, Afzal M. Dogar, Lukas C. Kühn, Giovanna Ambrosini, Sylvain Pradervand
Publikováno v:
PloS one, vol. 13, no. 11, pp. e0206823
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206823 (2018)
PLoS ONE, 13 (11)
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206823 (2018)
PLoS ONE, 13 (11)
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in m
Autor:
Jonathan Hall, Martina Roos, Julian A. Zagalak, Luca F R Gebert, Karin J. Metzner, Valentina Vongrad, Afzal M. Dogar, Boris Guennewig
Functional microRNAs (miRNAs) are produced from both arms of their precursors (pre-miRNAs). Their abundances vary in context-dependent fashion spatiotemporarily and there is mounting evidence of regulatory interplay between them. Here, we introduce c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99fe85a6206f2eed2398108eaf86ac8b
https://www.zora.uzh.ch/id/eprint/87952/
https://www.zora.uzh.ch/id/eprint/87952/
Autor:
Afzal M. Dogar, Xiaoye Schneider-Yin, Chantal Béguin, Elisabeth I. Minder, Jasmin Barman-Aksözen
Publikováno v:
Blood cells, moleculesdiseases. 51(3)
Erythropoietic protoporphyria (EPP) results from partial deficiency of ferrochelatase (FECH). Genetically, EPP patients differ from asymptomatic mutation carriers at the unmutated FECH allele, the expression of which is modulated by single nucleotide
Publikováno v:
Nucleic Acid Therapeutics
Experiments conducted with micro RNA (miRNA) mimics often result in subtle phenotypic changes and hence require careful controls. A commonly used type of control reagent in the antisense/RNA interference fields is the mismatched sequence. However it