Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Afshin, Raouf"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-7 (2023)
Abstract Stromal vascular fraction (SVF) cells, and the adipose-derived mesenchymal stem cells they contain, have shown enhanced wound healing in vitro and in vivo, yet their clinical application has been limited. In this regard, understanding the me
Externí odkaz:
https://doaj.org/article/e7a0c44f73514165a9a54b89d893e28d
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/11f25c046a8c405bac708af2d8d1a65a
Publikováno v:
Methods and Protocols, Vol 6, Iss 5, p 87 (2023)
The scratch assay is an in vitro assay that allows for high-throughput quantification of wound closure by keratinocytes and fibroblasts with relative ease. However, this assay is amenable to experimental variables, which can result in false-positive
Externí odkaz:
https://doaj.org/article/a84413a2e28e470aa00d2030ec0a5574
Autor:
Sumanta Chatterjee, Vasudeva Bhat, Alexei Berdnikov, Jiahui Liu, Guihua Zhang, Edward Buchel, Janice Safneck, Aaron J. Marshall, Leigh C. Murphy, Lynne-Marie Postovit, Afshin Raouf
Publikováno v:
iScience, Vol 19, Iss , Pp 388-401 (2019)
Summary: Breast cancer-induced activated fibroblasts support tumor progression. However, the role of normal fibroblasts in tumor progression remains controversial. In this study, we used modified patient-derived organoid cultures and demonstrate that
Externí odkaz:
https://doaj.org/article/e2ec1c1892864a9d9d4ce305d8e93e07
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background Adult stem cells and progenitors are responsible for breast tissue regeneration. Human breast epithelial progenitors are organized in a lineage hierarchy consisting of bipotent progenitors (BPs), myoepithelial- and luminal-restric
Externí odkaz:
https://doaj.org/article/417c416fdf494a7e9262c5848c3e18e1
Autor:
Pratima Basak, Sumanta Chatterjee, Vasudeva Bhat, Alice Su, Hyerang Jin, Victoria Lee-Wing, Qian Liu, Pingzhao Hu, Leigh C Murphy, Afshin Raouf
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 4, Pp 1518-1532 (2018)
Background/Aims: Blocking estrogen signaling with endocrine therapies (Tamoxifen or Fulverstrant) is an effective treatment for Estrogen Receptor-α positive (ER+) breast cancer tumours. Unfortunately, development of endocrine therapy resistance (ETR
Externí odkaz:
https://doaj.org/article/b171bdee3dfa471c89d36a472306c79a
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2018)
Abstract Background Normal human breast epithelial cells are maintained by the proliferation and differentiation of different human breast epithelial progenitors (HBEPs). However, these progenitor subsets can only be obtained at low frequencies, limi
Externí odkaz:
https://doaj.org/article/e8a123df9e3e442cabc3ef51483fa0db
Autor:
Sumanta Chatterjee, Pratima Basak, Edward Buchel, Janice Safneck, Leigh C. Murphy, Michael Mowat, Sam K. Kung, Peter Eirew, Connie J. Eaves, Afshin Raouf
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 196-211 (2018)
Summary: Human breast cancer cells are known to activate adjacent “normal-like” cells to enhance their own growth, but the cellular and molecular mechanisms involved are poorly understood. We now show by both phenotypic and functional measurement
Externí odkaz:
https://doaj.org/article/cb6ea7e92cf84eb1ab188f9e5865042d
Autor:
Sandra E. Dunn, Connie J. Eaves, Hans-Dieter Royer, Isabelle M. Berquin, Pauline Johnson, Afshin Raouf, Anna L. Stratford, Lawrence Lee, Alastair H. Davies, Arezoo Astanehe, Jing Wang, Kaiji Hu, Jennifer H. Law, Kristen M. Reipas, Abbas Fotovati, Karen To
Supplementary Methods and Materials, Figures 1-6 from Y-Box Binding Protein-1 Induces the Expression of CD44 and CD49f Leading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82df214052211b4407e274eea205de
https://doi.org/10.1158/0008-5472.22386402.v1
https://doi.org/10.1158/0008-5472.22386402.v1
Autor:
Leigh C. Murphy, Edward W. Buchel, Janice R. Safneck, Aaron J. Marshall, Guihua Zhang, Jiahui Liu, Alexei Berdnikov, Sumanta Chatterjee, Afshin Raouf, Lynne-Marie Postovit, Vasudeva Bhat
Publikováno v:
iScience, Vol 19, Iss, Pp 388-401 (2019)
Summary: Breast cancer-induced activated fibroblasts support tumor progression. However, the role of normal fibroblasts in tumor progression remains controversial. In this study, we used modified patient-derived organoid cultures and demonstrate that