Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery

Autor: Christian Crouzet, Robert H. Wilson, Donald Lee, Afsheen Bazrafkan, Bruce J. Tromberg, Yama Akbari, Bernard Choi

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 1 (2020)

Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA. Cerebral blood flow (CBF) pulsatility immediately, during, and after CA

Externí odkaz: https://doaj.org/article/96e7b464e1a847bc9954ea9066dd2924

Cortical Anoxic Spreading Depolarization During Cardiac Arrest is Associated with Remote Effects on Peripheral Blood Pressure and Postresuscitation Neurological Outcome

Autor: Sangwoo Han, Mayra Isabel Contreras, Afsheen Bazrafkan, Masih Rafi, Shirin M. Dara, Ani Orujyan, Anais Panossian, Christian Crouzet, Beth Lopour, Bernard Choi, Robert H. Wilson, Yama Akbari

Publikováno v: Neurocritical care, vol 37, iss Suppl 1

Background Spreading depolarizations (SDs) are self-propagating waves of neuronal and glial depolarizations often seen in neurological conditions in both humans and animal models. Because SD is thought to worsen neurological injury, the role of SD in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee7e80579484b0e05c85be32ee970b6
https://pubmed.ncbi.nlm.nih.gov/35332425

Contributions of diffuse and directed flow in turbid media to absolute measurements of tissue perfusion and oxygen consumption using laser speckle and spatial frequency domain imaging

Autor: Masih A. Rafi, Christian Crouzet, Bernard Choi, Afsheen Bazrafkan, Yama Akbari, Robert H. Wilson

Publikováno v: Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics.

We describe the development of a perturbation-free technique to measure tissue blood flow and metabolic rate of oxygen (MRO2) using LSI and SFDI. Analytical (diffusion) and computational (Monte Carlo) models are employed to characterize the contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56b2e384dc1a5bebea8076c348fb4cb8
https://doi.org/10.1117/12.2579039

Neural Correlates of Consciousness at Near-Electrocerebral Silence in an Asphyxial Cardiac Arrest Model

Autor: Yama Akbari, Donald Lee, Tin J. Dinh, Danny Siu, Wei Xiong, Josue Orellana, Afsheen Bazrafkan, Lauren G. Lee, Maryam Hosseini Farahabadi, Beth A. Lopour

Publikováno v: Brain connectivity, vol 7, iss 3
Lee, DE; Lee, LG; Siu, D; Bazrafkan, AK; Farahabadi, MH; Dinh, TJ; et al.(2017). Neural Correlates of Consciousness at Near-Electrocerebral Silence in an Asphyxial Cardiac Arrest Model.. Brain connectivity, 7(3), 172-181. doi: 10.1089/brain.2016.0471. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2zf4k7b0
Brain Connectivity

Recent electrophysiological studies have suggested surges in electrical correlates of consciousness (i.e., elevated gamma power and connectivity) after cardiac arrest (CA). This study examines electrocorticogram (ECoG) activity and coherence of the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a5834727fe4a317e3a3c52604603bf
https://doi.org/10.1089/brain.2016.0471

Spreading depolarization and repolarization during cardiac arrest as an ultra-early marker of neurological recovery in a preclinical model

Autor: Maziar Moslehyazdi, Niki Maki, Donald Lee, Robert H. Wilson, Mohammad Torabzadeh, Justin H. Pham, Ayushi H. Patel, Afsheen Bazrafkan, Masih A. Rafi, Beth A. Lopour, Bernard Choi, Bruce J. Tromberg, Yama Akbari, Christian Crouzet, Brooke E. Hjelm, Oswald Steward, Dishant Donga

Spreading depolarization (SD) accompanies numerous neurological conditions, including migraine, stroke, and traumatic brain injury. There is significant interest in understanding the relationship between SD and neuronal injury. However, characteristi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda028242bc1fae908ec31d022766099
https://doi.org/10.1101/786210