Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Afsaneh Abdolzade"'
Autor:
Arthur J. Van De Vyver, Antje-Christine Walz, Mariette S. Heins, Afsaneh Abdolzade-Bavil, Thomas E. Kraft, Inja Waldhauer, Michael B. Otteneder
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Monoclonal antibodies play an important role in the treatment of various diseases. However, the development of these drugs against neurological disorders where the drug target is located in the brain is challenging and requires a good understanding o
Externí odkaz:
https://doaj.org/article/3178277d91194c33ad0c97715f1819eb
Autor:
Sagar Lonial, Afsaneh Abdolzade-Bavil, Asher Chanan-Khan, Markus Ruehle, Farima Barmaki-Rad, Nikhil C. Munshi, Suraj Chandwani, George Somlo, Kevin R. Kelly, Sundar Jagannath, Ashot Minasyan, Sumit Madan, Andrea Wartenberg-Demand, Eva Herrmann-Keiner, Todd M. Zimmerman, Leonard T. Heffner, Sikander Ailawadhi, Faiza Rharbaoui, Thomas Haeder, David S. Siegel, Kenneth C. Anderson
Publikováno v:
The Lancet Haematology. 8:e794-e807
Summary Background Indatuximab ravtansine (BT062) is an antibody-drug conjugate that binds to CD138 and synergistically enhances the antitumor activity of lenalidomide in preclinical models of multiple myeloma. This phase 1/2a study was done to deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0615d00fca68dbeca53ac09dba128790
https://doi.org/10.1016/s2352-3026(21)00208-8
https://doi.org/10.1016/s2352-3026(21)00208-8
Autor:
Christian Künzel, Kay Stubenrauch, Alfred Engel, Eginhard Schick, Afsaneh Abdolzade-Bavil, Mirko Pleitner
Publikováno v:
Bioanalysis. 13:253-263
Aim: Development and qualification of an easy-to-use ELISA for detection of IgM anti-drug antibodies (ADA) and its use in a clinical Phase I trial. Results & methodology: During the assay development two positive control (PC) approaches, the preparat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45a0cbf568e26f70a50eeaf35027800
https://doi.org/10.4155/bio-2020-0308
https://doi.org/10.4155/bio-2020-0308
Autor:
Kay Stubenrauch, Julia Heinrich, Janis Brockhaus, Uwe Wessels, Markus Zadak, Afsaneh Abdolzade-Bavil, Mirko Ritter, Astrid Reiser
Publikováno v:
Bioanalysis. 10(11)
Aim: High drug concentrations in ocular fluids after intravitreal administration preclude the use of drug-sensitive immunoassays. A drug-tolerant immunoassay is therefore desirable for immunogenicity testing in ophthalmology. Experimental: Immune com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceae4b94eb73a58ff7ff4f59543e7cef
https://pubmed.ncbi.nlm.nih.gov/29637799
https://pubmed.ncbi.nlm.nih.gov/29637799
Autor:
Andreas Lammerich, Laurie Pukac, Matthias Görlach, Wenyan David Shen, Christian Dr. Scheckermann, Bridget A. Cooksey, Hermann Allgaier, Afsaneh Abdolzade-Bavil, Patrick Liu, Thomas Kaufman, Philip A. Krasney, Aaron von Kerczek
Publikováno v:
The Journal of Clinical Pharmacology. 56:186-194
To assess the basis of the different half-lives of long-acting human granulocyte colony-stimulating factor (G-CSF) drugs, the effect of neutrophil elastase on lipegfilgrastim and pegfilgrastim was investigated. Sensitivity to human neutrophil elastas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::891c2c898fedf122d45f0da2cdf1d736
https://doi.org/10.1002/jcph.578
https://doi.org/10.1002/jcph.578
Autor:
Afsaneh, Abdolzade-Bavil, Aaron, von Kerczek, Bridget A, Cooksey, Thomas, Kaufman, Philip A, Krasney, Laurie, Pukac, Matthias, Görlach, Andreas, Lammerich, Christian, Scheckermann, Hermann, Allgaier, Wenyan David, Shen, Patrick M, Liu
Publikováno v:
Journal of clinical pharmacology. 56(2)
To assess the basis of the different half-lives of long-acting human granulocyte colony-stimulating factor (G-CSF) drugs, the effect of neutrophil elastase on lipegfilgrastim and pegfilgrastim was investigated. Sensitivity to human neutrophil elastas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::602ea20a388398745496cb6ed1b9cb74
https://pubmed.ncbi.nlm.nih.gov/26105553
https://pubmed.ncbi.nlm.nih.gov/26105553
Autor:
Afsaneh Abdolzade-Bavil, Lothar Goretzki, Jonas Anders, Michaela Kröger, Robertus Hendriks, Scott Hayes
Publikováno v:
PROTEOMICS. 4:1397-1405
Standardized sample preparation to reduce proteome complexity facilitates subsequent proteome analysis. Here we describe a robust sequential extraction method that enables simple fractionation of proteins in their native state according to their subc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089cf873793b1e6c2d432eb465390a9b
https://doi.org/10.1002/pmic.200300710
https://doi.org/10.1002/pmic.200300710
Publikováno v:
Current medical research and opinion. 30(12)
Two phase I, single-blind (subject blinded to treatment), randomized studies were conducted to assess the pharmacodynamics, pharmacokinetics, safety, and tolerability of lipegfilgrastim compared with pegfilgrastim in healthy adult volunteers.Study 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53972df1a9c6ed73b8120c086d057ce
https://pubmed.ncbi.nlm.nih.gov/25251999
https://pubmed.ncbi.nlm.nih.gov/25251999
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799587
Peroxisomes exhibit a heterogeneous morphological appearance in rat liver tissue. In this respect, the isolation and subsequent biochemical characterization of peroxisome species from different subcellular prefractions should help to solve the questi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98b91d611e356eac4530b864757cb2e4
https://doi.org/10.1007/978-1-61779-959-4_6
https://doi.org/10.1007/978-1-61779-959-4_6
Autor:
Ramona Rotaru, Sabine Angermüller, Joachim Kirsch, Markus Islinger, Gerhard Weber, Afsaneh Abdolzade-Bavil
Publikováno v:
Neuromethods ISBN: 9781617791109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4019c478ef76ea51ce222b34e930336
https://doi.org/10.1007/978-1-61779-111-6_3
https://doi.org/10.1007/978-1-61779-111-6_3