Zobrazeno 1 - 10
of 46
pro vyhledávání: '"African iron overload"'
Autor:
V V Pavan Kedar Mukthinuthalapati, Ntokozo Ndlovu, Ghassan K. Abou-Alfa, Stephen Kimani, Elizabeth Y. Chiao, Vikash Sewram, Ashraf Omar Abdelaziz
Publikováno v:
JCO Global Oncology
More than 80% of global hepatocellular carcinoma (HCC) patients are estimated to occur in sub-Saharan Africa (SSA) and Eastern Asia. The most common risk factor of HCC in SSA is chronic hepatitis B virus (HBV) infection, with the incidence highest in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c94e93f1d439454b1a88e33c40432d6
https://doi.org/10.1200/go.20.00425
https://doi.org/10.1200/go.20.00425
Autor:
Victor Moyo, Christine E. McLaren, Rudo Makunike, Tracey A. Rouault, Clement F. Kiire, Thoko Saungweme, Hlosukwazi Khumalo, Innocent T. Gangaidzo, Victor R. Gordeuk
Publikováno v:
European Journal of Haematology. 60:28-34
Although HLA-linked hemochromatosis greatly increases the risk for hepatocellular carcinoma in people of European ancestry, iron overload in Africa is not thought to be etiologically related to this malignancy. To determine if African iron overload m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01abbaadc4554bb44900f162b8fd702a
https://doi.org/10.1111/j.1600-0609.1998.tb00993.x
https://doi.org/10.1111/j.1600-0609.1998.tb00993.x
Autor:
Victor Moyo, Victor R. Gordeuk, Elisha Mvundura, Thokozile Saungweme, Hlosukwazi Khumalo, Innocent T. Gangaidzo, Tracey A. Rouault, Z. A. R. Gomo, Mehdi Nouraie
Publikováno v:
Annals of Hematology. 88:1131-1136
In the setting of high dietary, several studies have provided evidence for a strong effect of both high dietary iron and an unidentified genetic locus on iron stores in Africans. To investigate whether these effects are discernible in the setting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d143115dca8a38aa63add351468da979
https://doi.org/10.1007/s00277-009-0718-6
https://doi.org/10.1007/s00277-009-0718-6
Autor:
Bianca Maria Ricerca, Aldo Morrone, Ilaria Cosentino, Francesca Clementina Radio, G. Gallusi, Silvia Majore, Francesco Binni, Paola Grammatico, Carmelilia De Bernardo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa98960f15ad270e9ebc5c4798c685f
http://hdl.handle.net/10807/41232
http://hdl.handle.net/10807/41232
Autor:
Lynette McNamara, Janice Paiker, Victor R. Gordeuk, Vanessa R. Panz, A. Patrick MacPhail, Frederick J. Raal, Barry I Joffe
Publikováno v:
Endocrine. 21:241-244
Endocrine disturbances, notably diabetes, have been well described as a complication of iron overload due to hereditary hemochromatosis and beta-thalassemia. Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis has also been well documented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdde1fdfb336e8136e028ef1b778f57
https://doi.org/10.1385/endo:21:3:241
https://doi.org/10.1385/endo:21:3:241
Publikováno v:
Hematology. 2003:40-61
In the past seven years numerous genes that influence iron homeostasis have been discovered. Dr. Beutler provides a brief overview of these genes, genes that encode HFE, DMT-1, ferroportin, transferrin receptor 2, hephaestin, and hepcidin to lay the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8230135bbde35d33f3f1651fa8e260b
https://doi.org/10.1182/asheducation-2003.1.40
https://doi.org/10.1182/asheducation-2003.1.40
Autor:
Carla Cardoso, Victor M. Moyo, José Fraga, Eugénia Cruz, Victor R. Gordeuk, Innocent T. Gangaidzo, Cidália Silva, Graça Porto, Graça Melo, Benvindo Justiça, José Carlos Oliveira, A. P. Macphail, Fernanda Bravo, Maria de Sousa, Z. A. R. Gomo, Jorge Areias
Publikováno v:
European Journal of Haematology. 67:110-118
To identify a new marker of expression of disease, independent of HFE genotype in patients with hereditary haemochromatosis (HHC), the total peripheral blood lymphocyte counts were analysed according to iron status in two groups of subjects with HFE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70f44e794b311c7782c9c6128edce443
https://doi.org/10.1034/j.1600-0609.2001.t01-1-00481.x
https://doi.org/10.1034/j.1600-0609.2001.t01-1-00481.x
Autor:
Victor Moyo, Ishmael Kasvosve, Victor R. Gordeuk, Innocent T. Gangaidzo, Birgitte Wuyts, Johan R. Boelaert, Hlosukwazi Khumalo, Elisha Mvundura, Z. A. R. Gomo, Thokozile Saungweme, Joris R. Delanghe
Publikováno v:
Clinical Chemistry. 46:1535-1539
Background: Genetic variants of human transferrin (TF) have been described, but little is known about their functional differences. We studied iron status according to TF phenotype in a healthy Zimbabwean population and in subjects at risk of African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15264c4e1adf80bf8917a38654b05383
https://doi.org/10.1093/clinchem/46.10.1535
https://doi.org/10.1093/clinchem/46.10.1535
Publikováno v:
Dermatologic Clinics. 13:57-63
Inherited forms of iron overload are common. HLA-linked hemochromatosis and possibly African iron overload are associated with a significant risk of developing hepatocellular carcinoma. Early diagnosis and treatment, before substantial iron overloadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35687acb074b400186dfd7fdb6e17431
https://doi.org/10.1016/s0733-8635(18)30107-4
https://doi.org/10.1016/s0733-8635(18)30107-4
Autor:
M A Crook
Publikováno v:
Annals of clinical biochemistry. 49(Pt 3)
In this edition, two articles describe cases of hyperferritinaemia. Thurlow et al. describe two novel mutations in the L-ferritin coding sequence associated with benign hyperferritinaemia showing abnormal ferritin glycosylation. Marshall et al. discu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2a0e4db11cd1e4d3a790324569ff5e
https://pubmed.ncbi.nlm.nih.gov/23440539
https://pubmed.ncbi.nlm.nih.gov/23440539