Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Afra Engelmann"'
Autor:
Antony W. Braithwaite, Afra Engelmann, C Rubio, Hamish Campbell, Michelle Wilson, Noelyn Hung, Reena Mehta, Tania L. Slatter, Gail Williams, Prudence Renshaw, Aaron Jeffs, Janice A. Royds, Margaret A. Baird
Publikováno v:
Blood. 117:5166-5177
The p53 protein is a pivotal tumor suppressor that is frequently mutated in many human cancers, although precisely how p53 prevents tumors is still unclear. To add to its complexity, several isoforms of human p53 have now been reported. The Δ133p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e099ca87c7b9a649bf45beea503140b1
https://doi.org/10.1182/blood-2010-11-321851
https://doi.org/10.1182/blood-2010-11-321851
Autor:
Jürgen Löhler, Marion Ziegler, Stephanie O. Harbers, Afra Engelmann, Meike Fischer, Michaela Rodenburg, Carol Stocking
Publikováno v:
Journal of Virology. 81:732-742
Murine leukemia viruses (MuLV) induce leukemia through a multistage process, a critical step being the activation of oncogenes through provirus integration. Transcription elements within the long terminal repeats (LTR) are prime determinants of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a7b1a968791ddeb00d1a6eae978fce
https://doi.org/10.1128/jvi.01430-06
https://doi.org/10.1128/jvi.01430-06
Publikováno v:
Journal of Biological Chemistry. 278:18-26
Archaea have a eukaryotic type of transcriptional machinery containing homologues of the transcription factors TATA-binding protein (TBP) and TFIIB (TFB) and a pol II type of RNA polymerase, whereas transcriptional regulators identified in archaeal g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc059834405341f24c4f65e11e1159c
https://doi.org/10.1074/jbc.m209250200
https://doi.org/10.1074/jbc.m209250200
Autor:
Zeinab Abdullah, Martin Krönke, Udo Siebolts, Claudia Wickenhauser, Afra Engelmann, Nikola Baschuk, Carol Stocking, Olaf Utermöhlen
Publikováno v:
Biological chemistry. 390(10)
Detailed knowledge of the immunologic properties of embryonic stem (ES) cells is a prerequisite for safe applications of ES cell-based regenerative medicine. Recently, the long-standing assumption that ES cells are ignored by immunocompetent hosts wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bb90a7bb01863872ce870c87bb23b6
https://pubmed.ncbi.nlm.nih.gov/19642871
https://pubmed.ncbi.nlm.nih.gov/19642871
Autor:
Andrea Schüler, Martin Forster, Eric N. Olson, Maike Schwieger, Robert K. Slany, Afra Engelmann, Peter J. M. Valk, Michael Arnold, Ruud Delwel, Jürgen Löhler, Carol Stocking
Publikováno v:
Blood, 114(12), 2476-2488. American Society of Hematology
Acute myelogenous leukemia is driven by leukemic stem cells (LSCs) generated by mutations that confer (or maintain) self-renewal potential coupled to an aberrant differentiation program. Using retroviral mutagenesis, we identified genes that generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f34edaac24a8d5f0af7dbba383cff9
https://pure.eur.nl/en/publications/d35ae0b1-c29e-4bc1-a59f-50957cdc2ad5
https://pure.eur.nl/en/publications/d35ae0b1-c29e-4bc1-a59f-50957cdc2ad5
Autor:
Maike Schwieger, Eric N. Olson, Michael Arnold, Carol Stocking, Afra Engelmann, Kristoffer Weber, Andrea Schüler, Ursula Müller, Stefan Horn
Publikováno v:
Blood. 111(9)
Mef2c is a MADS (MCM1-agamous–deficient serum response factor) transcription factor best known for its role in muscle and cardiovascular development. A causal role of up-regulated MEF2C expression in myelomonocytic acute myeloid leukemia (AML) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11a2314d818f9ea2a8ec7f986410fa3
https://pubmed.ncbi.nlm.nih.gov/18326819
https://pubmed.ncbi.nlm.nih.gov/18326819
Autor:
Afra Engelmann, Winfried Boos, Qiuhao Qu, Gudrun Vierke, Michael Thomm, Sung-Jae Lee, Reinhold Horlacher, Carina Hebbeln
Publikováno v:
The Journal of biological chemistry. 278(2)
We report the characterization of TrmB, a protein of 38,800 apparent molecular weight, that is involved in the maltose-specific regulation of a gene cluster in Thermococcus litoralis, malE malF malG orf trmB malK, encoding a binding protein-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cedd4d0303b0987c60a583b92a86db42
https://pubmed.ncbi.nlm.nih.gov/12426307
https://pubmed.ncbi.nlm.nih.gov/12426307