Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Afra Anjum"'
Autor:
Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Markus Joppich, Sophia Brambs, Aleksandar Janjic, Oliver Popp, Daniel Nixdorf, Valeria Fumagalli, Nora Schmidt, Vivien Polewka, Afra Anjum, Viktoria Knottenberg, Luke Eivers, Lucas E. Wange, Christoph Gold, Marieluise Kirchner, Maximilian Muenchhoff, Johannes C. Hellmuth, Clemens Scherer, Raquel Rubio-Acero, Tabea Eser, Flora Deák, Kerstin Puchinger, Niklas Kuhl, Andreas Linder, Kathrin Saar, Lukas Tomas, Christian Schulz, Andreas Wieser, Wolfgang Enard, Inge Kroidl, Christof Geldmacher, Michael von Bergwelt-Baildon, Oliver T. Keppler, Mathias Munschauer, Matteo Iannacone, Ralf Zimmer, Philipp Mertins, Norbert Hubner, Michael Hoelscher, Steffen Massberg, Konstantin Stark, Leo Nicolai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Infection with SARS-COV-2 can result in self-limited upper airway infection or progress to a more systemic inflammatory condition including pneumonic COVID-19. Here the authors utilise a multi-omics approach to interrogate the immune response of pati
Externí odkaz:
https://doaj.org/article/25f8c8382ab44535bbd9a714a216c8f8
Autor:
Leo Nicolai, Rainer Kaiser, Raphael Escaig, Marie-Louise Hoffknecht, Afra Anjum, Alexander Leunig, Joachim Pircher, Andreas Ehrlich, Michael Lorenz, Hellen Ishikawa-Ankerhold, William C. Aird, Steffen Massberg, Florian Gaertner
Publikováno v:
Haematologica, Vol 107, Iss 7 (2021)
Visualizing cell behavior and effector function on a single cell level has been crucial for understanding key aspects of mammalian biology. Due to their small size, large number and rapid recruitment into thrombi, there is a lack of data on fate and
Externí odkaz:
https://doaj.org/article/43e3282e3a9f488895e15ffcec411f2e
Autor:
Rainer Kaiser, Alexander Leunig, Kami Pekayvaz, Oliver Popp, Markus Joppich, Vivien Polewka, Raphael Escaig, Afra Anjum, Marie-Louise Hoffknecht, Christoph Gold, Sophia Brambs, Anouk Engel, Sven Stockhausen, Viktoria Knottenberg, Anna Titova, Mohamed Haji, Clemens Scherer, Maximilian Muenchhoff, Johannes C. Hellmuth, Kathrin Saar, Benjamin Schubert, Anne Hilgendorff, Christian Schulz, Stefan Kääb, Ralf Zimmer, Norbert Hübner, Steffen Massberg, Philipp Mertins, Leo Nicolai, Konstantin Stark
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Neutrophils provide a critical line of defense in immune responses to various pathogens, inflicting self-damage upon transition to a hyperactivated, procoagulant state. Recent work has highlighted proinflammatory neutrophil phenotypes contributing to
Externí odkaz:
https://doaj.org/article/6c76effe0be0417985fb0f08c49e4b8c
Autor:
Rainer Kaiser, Afra Anjum, Lisa Maria Kammerer, Quentin Loew, Anastassia Akhalkatsi, Dario Rossaro, Raphael Escaig, Augustin Droste zu Senden, Ben Raude, Michael Lorenz, Christoph Gold, Kami Pekayvaz, Thomas Brocker, Jan Kranich, Julian Walter Holch, Karsten Spiekermann, Steffen Massberg, Florian Gaertner, Leo Nicolai
Publikováno v:
Blood.
Platelets are first responders in thrombosis and hemostasis, but also central players in inflammation. Compared to platelets recruited to thrombi, immune-responsive platelets use distinct effector functions including Arp2/3-dependent migration along
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6486acdfc22fae7f005481e7d88d084
https://doi.org/10.1182/blood.2022019210
https://doi.org/10.1182/blood.2022019210
Autor:
Rainer Kaiser, Raphael Escaig, Jan Kranich, Marie-Louise Hoffknecht, Afra Anjum, Vivien Polewka, Magdalena Mader, Wenbo Hu, Larissa Belz, Christoph Gold, Anna Titova, Michael Lorenz, Kami Pekayvaz, Stefan Kääb, Florian Gaertner, Konstantin Stark, Thomas Brocker, Steffen Massberg, Leo Nicolai
Publikováno v:
Blood
Impairment of vascular integrity is a hallmark of inflammatory diseases. We recently reported that single immune-responsive platelets migrate and reposition themselves to sites of vascular injury to prevent bleeding. However, it remains unclear how s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34cc7d46a0dbd97f65def342bb12773
https://pubmed.ncbi.nlm.nih.gov/35834285
https://pubmed.ncbi.nlm.nih.gov/35834285
Autor:
Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Markus Joppich, Sophia Brambs, Aleksandar Janjic, Oliver Popp, Daniel Nixdorf, Valeria Fumagalli, Nora Schmidt, Vivien Polewka, Afra Anjum, Viktoria Knottenberg, Luke Eivers, Lucas E. Wange, Christoph Gold, Marieluise Kirchner, Maximilian Muenchhoff, Johannes C. Hellmuth, Clemens Scherer, Raquel Rubio-Acero, Tabea Eser, Flora Deák, Kerstin Puchinger, Niklas Kuhl, Andreas Linder, Kathrin Saar, Lukas Tomas, Christian Schulz, Andreas Wieser, Wolfgang Enard, Inge Kroidl, Christof Geldmacher, Michael von Bergwelt-Baildon, Oliver T. Keppler, Mathias Munschauer, Matteo Iannacone, Ralf Zimmer, Philipp Mertins, Norbert Hubner, Michael Hoelscher, Steffen Massberg, Konstantin Stark, Leo Nicolai
Publikováno v:
Nature Communications
The antiviral immune response to SARS-CoV-2 infection can limit viral spread and prevent development of pneumonic COVID-19. However, the protective immunological response associated with successful viral containment in the upper airways remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6868e3511307cae2a86591340303a260
https://pubmed.ncbi.nlm.nih.gov/35197461
https://pubmed.ncbi.nlm.nih.gov/35197461
Autor:
Karsten Spiekermann, Konstantin Stark, Raphael Escaig, Steffen Massberg, Anna Titova, Alexander Leunig, Vivien Polewka, Dario Rossaro, Leo Nicolai, Luke Eivers, Afra Anjum, Marie-Louise Hoffknecht, Rainer Kaiser, Kami Pekayvaz, Eva Riedlinger, Matteo Iannacone
Summary paragraphVaccines against SARS-CoV-2 are based on a range of novel vaccine platforms, with adenovirus-based approaches (like ChAdOx1 nCov-19) being one of them. Recently a rare and novel complication of SARS-CoV-2 targeted adenovirus vaccines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e087e8559e1b50438b17dff51547bb57
https://doi.org/10.1101/2021.06.29.450356
https://doi.org/10.1101/2021.06.29.450356
Autor:
Leo Nicolai, Alexander Leunig, Kami Pekayvaz, Max Esefeld, Afra Anjum, Justina Rath, Eva Riedlinger, Vincent Ehreiser, Magdalena Mader, Luke Eivers, Marie-Louise Hoffknecht, Zhe Zhang, Daniela Kugelmann, Dario Rossaro, Raphael Escaig, Rainer Kaiser, Vivien Polewka, Anna Titova, Tobias Petzold, Karsten Spiekermann, Matteo Iannacone, Thomas Thiele, Andreas Greinacher, Konstantin Stark, Steffen Massberg
Publikováno v:
Blood
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are based on a range of novel platforms, with adenovirus-based approaches (like ChAdOx1 nCov-19) being one of them. Recently, a novel complication of SARS-CoV-2–targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba3f4de998695784601b8f6f0490a48
Autor:
Sven Stockhausen, Clemens Scherer, Philipp Mertins, Leo Nicolai, Raphael Escaig, Christoph Gold, Maximilian Muenchhoff, Alexander Leunig, Vivien Polewka, Anna Titova, Christian Schulz, Johannes C. Hellmuth, Anouk Engel, Viktoria Knottenberg, Afra Anjum, Steffen Massberg, Markus Joppich, Ralf Zimmer, Kami Pekayvaz, Rainer Kaiser, Norbert Hubner, Sophia Brambs, Anne Hilgendorff, Konstantin Stark, Benjamin Schubert, Oliver Popp, Mohamed Haji, Marie-Louise Hoffknecht, Stefan Kääb, Kathrin Saar
Publikováno v:
JCI Insight
JCI insight 6:e150862 (2021)
JCI insight 6:e150862 (2021)
Neutrophils provide a critical line of defense in immune responses to various pathogens, inflicting self-damage upon transition to a hyperactivated, procoagulant state. Recent work has highlighted proinflammatory neutrophil phenotypes contributing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b7a498a87215354c4fc8b3cb1956ef