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Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system

Autor: Afia Usman, Dongkyeong Kim, Shoeb Ikhlas, Dongsheng Cai

Publikováno v: Life Science Alliance

Murine neural stem cell exosomes/microvesicles can work to reduce SARS-CoV-2, an effect that can be adaptively enhanced via viral RNA fragment stimulation, which requires the PIWI-piRNA system.
Murine neural stem cells (NSCs) were recently shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7104bbcc65327fbc80b5961320b28489
https://pubmed.ncbi.nlm.nih.gov/34862272

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In vitro study to evaluate the cytotoxicity of BPA analogues based on their oxidative and genotoxic potential using human peripheral blood cells

Autor: Afia Usman, Shoeb Ikhlas, Masood Ahmad

Publikováno v: Toxicology in Vitro. 60:229-236

Although Bisphenol-A (BPA) has been found to exhibit toxicological properties such as genotoxicity and oxidative stress, yet there is very little data available on its analogues. Since the replacement of BPA by its analogues, their presence has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b72c16d255134c3525b99ee835d173
https://doi.org/10.1016/j.tiv.2019.06.001

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Occurrence, toxicity and endocrine disrupting potential of Bisphenol-B and Bisphenol-F: A mini-review

Autor: Afia Usman, Shoeb Ikhlas, Masood Ahmad

Publikováno v: Toxicology letters. 312

Recent imposition of restriction on the use of Bisphenol-A (BPA) paved the way for entry of its analogues in the market. Bisphenol-B and Bisphenol-F are the major analogues of commercial value. Thus, their increasing production and application make t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f0b0dbde378a045da63cab30db9fde
https://pubmed.ncbi.nlm.nih.gov/31399229

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From BPA to its analogues: Is it a safe journey?

Autor: Masood Ahmad, Afia Usman

Publikováno v: Chemosphere. 158:131-142

Bisphenol-A (BPA) is one of the most abundant synthetic chemicals in the world due to its uses in plastics. Its widespread exposure vis-a-vis low dose effects led to a reduction in its safety dose and imposition of ban on its use in infant feeding bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81e2e7c656e2389421391a48706bde9
https://doi.org/10.1016/j.chemosphere.2016.05.070

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Computational study suggesting reconsideration of BPA analogues based on their endocrine disrupting potential estimated by binding affinities to nuclear receptors

Autor: Afia Usman, Masood Ahmad

Publikováno v: Ecotoxicology and environmental safety. 171

Due to its endocrine disrupting nature Bisphenol-A (BPA), a chemical used in the plastic industry was placed under a ban which provided an incentive for its replacement by bisphenol and non-bisphenol based plasticizers. The use of bisphenol replaceme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec409f0df2cbf9f9218e05c890f1f338
https://pubmed.ncbi.nlm.nih.gov/31369940

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Binding of Bisphenol-F, a bisphenol analogue, to calf thymus DNA by multi-spectroscopic and molecular docking studies

Autor: Afia Usman, Masood Ahmad

Publikováno v: Chemosphere. 181

BPF (Bisphenol-F), a member of the bisphenol family, having a wide range of industrial applications is gradually replacing Bisphenol-A. It is a recognized endocrine disrupting chemical (EDC). EDCs have been implicated in increased incidences of breas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8996c1a5162518ef0a2cb74b92a9d75
https://pubmed.ncbi.nlm.nih.gov/28463728

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