Synthesis of lipid-carbohydrate-peptidyl-RNA conjugates to explore the limits imposed by the substrate specificity of cell wall enzymes on the acquisition of drug resistance

Autor: Michel Arthur, Tom Brown, Nicolas Sakkas, Ahmed Bouhss, Delphine Patin, Dominique Mengin-Lecreulx, Affaf El Sagheer, Coralie Hoareau, Matthieu Fonvielle, Laura Iannazzo, Mélanie Etheve-Quelquejeu

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2018, 24 (56), pp.14911-14915. ⟨10.1002/chem.201802360⟩
Chemistry-A European Journal, 2018, 24 (56), pp.14911-14915. ⟨10.1002/chem.201802360⟩

International audience; Conjugation of RNA with multiple partners to obtain mimics of complex biomolecules is limited by the identification of orthogonal reactions. Here, lipid-carbohydrate-peptidyl-RNA conjugates were obtained by post-functionalizat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a61e985fea19de10ec136369ceae6b
https://hal.sorbonne-universite.fr/hal-01962025