Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Afd Chemical Biology and Drug Discovery"'
Autor:
Liu, Zhicheng, Li, Xia, Lu, Zhongkai, Qin, Xinfang, Hong, Haofei, Zhou, Zhifang, Pieters, Roland J., Shi, Jie, Wu, Zhimeng, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
Journal of Pharmaceutical Sciences, 111(10), 2719. John Wiley and Sons Inc.
Globotriaosylceramide (Gb3 or CD77) is a tumor-associated carbohydrate antigen implicated in several types of cancer that serves as a potential cancer marker for developing target-specific diagnosis and therapy. However, the development of Gb3-target
Autor:
Hooijschuur, Kevin, Liu, Xiufen, Grootendorst, Anna, Pieterman, Ines, Sastre Toraño, Javier, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
Electrophoresis, 44(3-4), 395. Wiley-VCH Verlag
The analysis of low-abundant compounds with capillary zone electrophoresis–drift-tube ion mobility spectrometry–mass spectrometry (CZE–DTIMS–MS) is compromised due to the low injectable sample volumes in CZE and low duty cycle in DTIMS. Fritl
Autor:
Goudsmit-Harzevoort, Barbara, Lansu, Angelique, Baatsen, Michiel L.J., von der Heydt, Anna S., de Winter, Niels J., Zhang, Yurui, Abe-Ouchi, Ayako, de Boer, Agatha, Chan, Wing Le, Donnadieu, Yannick, Hutchinson, David K., Knorr, Gregor, Ladant, Jean Baptiste, Morozova, Polina, Niezgodzki, Igor, Steinig, Sebastian, Tripati, Aradhna, Zhang, Zhongshi, Zhu, Jiang, Ziegler, Martin, Stratigraphy and paleontology, Sub Dynamics Meteorology, Sub Physical Oceanography, Afd Chemical Biology and Drug Discovery, Marine and Atmospheric Research
Publikováno v:
Paleoceanography and Paleoclimatology, 38(3):e2022PA004532, 1-18. John Wiley & Sons, Ltd
Goudsmit-Harzevoort, B, Lansu, A, Baatsen, M L J, von der Heydt, A S, de Winter, N J, Zhang, Y, Abe-Ouchi, A, de Boer, A, Chan, W-L, Donnadieu, Y, Hutchinson, D K, Knorr, G, Ladant, J-B, Morozova, P, Niezgodzki, I, Steinig, S, Tripati, A, Zhang, Z, Zhu, J & Ziegler, M 2022 ' The relationship between the global mean deep-sea and surface temperature during the Early Eocene ' Earth and Space Science Open Archive . https://doi.org/10.1002/essoar.10512236.1
Paleoceanography and Paleoclimatology
Paleoceanography and Paleoclimatology, 2023, 38 (3), ⟨10.1029/2022pa004532⟩
Paleoceanography and Paleoclimatology, 28(3):e2022PA004532. Wiley-Blackwell Publishing, Inc.
Paleoceanography and Paleoclimatology, 38(3). Wiley Online Library
Goudsmit-Harzevoort, B, Lansu, A, Baatsen, M L J, von der Heydt, A S, de Winter, N J, Zhang, Y, Abe-Ouchi, A, de Boer, A, Chan, W L, Donnadieu, Y, Hutchinson, D K, Knorr, G, Ladant, J B, Morozova, P, Niezgodzki, I, Steinig, S, Tripati, A, Zhang, Z, Zhu, J & Ziegler, M 2023, ' The Relationship Between the Global Mean Deep-Sea and Surface Temperature During the Early Eocene ', Paleoceanography and Paleoclimatology, vol. 38, no. 3, e2022PA004532, pp. 1-18 . https://doi.org/10.1029/2022PA004532
Goudsmit-Harzevoort, B, Lansu, A, Baatsen, M L J, von der Heydt, A S, de Winter, N J, Zhang, Y, Abe-Ouchi, A, de Boer, A, Chan, W-L, Donnadieu, Y, Hutchinson, D K, Knorr, G, Ladant, J-B, Morozova, P, Niezgodzki, I, Steinig, S, Tripati, A, Zhang, Z, Zhu, J & Ziegler, M 2023, ' The relationship between the global mean deep-sea and surface temperature during the Early Eocene ', Paleoceanography and Paleoclimatology, vol. 38, no. 3, e2022PA004532 . https://doi.org/10.1029/2022PA004532
Goudsmit-Harzevoort, B, Lansu, A, Baatsen, M L J, von der Heydt, A S, de Winter, N J, Zhang, Y, Abe-Ouchi, A, de Boer, A, Chan, W-L, Donnadieu, Y, Hutchinson, D K, Knorr, G, Ladant, J-B, Morozova, P, Niezgodzki, I, Steinig, S, Tripati, A, Zhang, Z, Zhu, J & Ziegler, M 2022 ' The relationship between the global mean deep-sea and surface temperature during the Early Eocene ' Earth and Space Science Open Archive . https://doi.org/10.1002/essoar.10512236.1
Paleoceanography and Paleoclimatology
Paleoceanography and Paleoclimatology, 2023, 38 (3), ⟨10.1029/2022pa004532⟩
Paleoceanography and Paleoclimatology, 28(3):e2022PA004532. Wiley-Blackwell Publishing, Inc.
Paleoceanography and Paleoclimatology, 38(3). Wiley Online Library
Goudsmit-Harzevoort, B, Lansu, A, Baatsen, M L J, von der Heydt, A S, de Winter, N J, Zhang, Y, Abe-Ouchi, A, de Boer, A, Chan, W L, Donnadieu, Y, Hutchinson, D K, Knorr, G, Ladant, J B, Morozova, P, Niezgodzki, I, Steinig, S, Tripati, A, Zhang, Z, Zhu, J & Ziegler, M 2023, ' The Relationship Between the Global Mean Deep-Sea and Surface Temperature During the Early Eocene ', Paleoceanography and Paleoclimatology, vol. 38, no. 3, e2022PA004532, pp. 1-18 . https://doi.org/10.1029/2022PA004532
Goudsmit-Harzevoort, B, Lansu, A, Baatsen, M L J, von der Heydt, A S, de Winter, N J, Zhang, Y, Abe-Ouchi, A, de Boer, A, Chan, W-L, Donnadieu, Y, Hutchinson, D K, Knorr, G, Ladant, J-B, Morozova, P, Niezgodzki, I, Steinig, S, Tripati, A, Zhang, Z, Zhu, J & Ziegler, M 2023, ' The relationship between the global mean deep-sea and surface temperature during the Early Eocene ', Paleoceanography and Paleoclimatology, vol. 38, no. 3, e2022PA004532 . https://doi.org/10.1029/2022PA004532
Our current understanding of global mean near-surface (land and sea) air temperature (GMSAT) during the Cenozoic era relies on paleo-proxy estimates of deep-sea temperature combined with assumed relationships between global mean deep-sea temperature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfd2cadefb134a856d7c2c5e722a412
https://research.vu.nl/en/publications/5f5ff7ca-b8b9-49db-b242-f41301c09d53
https://research.vu.nl/en/publications/5f5ff7ca-b8b9-49db-b242-f41301c09d53
Autor:
Scheibner, David, Salaheldin, Ahmed H, Bagato, Ola, Zaeck, Luca M, Mostafa, Ahmed, Blohm, Ulrike, Müller, Christin, Eweas, Ahmed F, Franzke, Kati, Karger, Axel, Schäfer, Alexander, Gischke, Marcel, Hoffmann, Donata, Lerolle, Solène, Li, Xuguang, Abd El-Hamid, Hatem S, Veits, Jutta, Breithaupt, Angele, Boons, Geert-Jan, Matrosovich, Mikhail, Finke, Stefan, Pleschka, Stephan, Mettenleiter, Thomas C, de Vries, Robert P, Abdelwhab, Elsayed M, Afd Chemical Biology and Drug Discovery, Sub Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
PLoS Pathogens, 19(2):e1011135. Public Library of Science
PLoS Pathogens, 19(2). Public Library of Science
PLoS Pathogens, 19(2). Public Library of Science
Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in
Autor:
Wood, Thomas M., Zeronian, Matthieu R., Buijs, Ned, Bertheussen, Kristine, Abedian, Hanieh K., Johnson, Aidan V., Pearce, Nicholas M., Lutz, Martin, Kemmink, Johan, Seirsma, Tjalling, Hamoen, Leendert W., Janssen, Bert J. C., Martin, Nathaniel I., Afd Chemical Biology and Drug Discovery, Sub Structural Biochemistry, Structural Biochemistry, Pharmacology
Publikováno v:
Chemical Science, 13(10), 2985-2991. Royal Society of Chemistry (RSC)
Chemical Science, 13(10), 2985-2991. ROYAL SOC CHEMISTRY
Chemical Science, 13(10), 2985-2991. Royal Society of Chemistry
Chemical Science, 13(10), 2985. Royal Society of Chemistry
Chemical Science, 13(10), 2985-2991. ROYAL SOC CHEMISTRY
Chemical Science, 13(10), 2985-2991. Royal Society of Chemistry
Chemical Science, 13(10), 2985. Royal Society of Chemistry
The continued rise of antibiotic resistance is a global concern that threatens to undermine many aspects of modern medical practice. Key to addressing this threat is the discovery and development of new antibiotics that operate by unexploited modes o
Autor:
Madunić, Katarina, Mayboroda, Oleg A., Zhang, Tao, Weber, Julia, Boons, Geert Jan, Morreau, Hans, van Vlierberghe, Ronald, van Wezel, Tom, Lageveen-Kammeijer, Guinevere S.M., Wuhrer, Manfred, Afd Chemical Biology and Drug Discovery, Sub Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
Theranostics, 12(10), 4498-4512. IVYSPRING INT PUBL
Theranostics, 12(10), 4498. Ivyspring International Publisher
Theranostics, 12(10), 4498. Ivyspring International Publisher
Cells are covered with a dense layer of carbohydrates, some of which are solely present on neoplastic cells. The so-called tumor-associated carbohydrate antigens (TACAs) are increasingly recognized as promising targets for immunotherapy. These carboh
Autor:
Di Maso, Matteo, Eussen, Simone R B M, Bravi, Francesca, Moro, Guido E, Agostoni, Carlo, Tonetto, Paola, Quitadamo, Pasqua A, Salvatori, Guglielmo, Profeti, Claudio, Kazmierska, Iwona, Vacca, Elisabetta, Decarli, Adriano, Stahl, Bernd, Bertino, Enrico, Ferraroni, Monica, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
Journal of Nutrition, 151(11), 3459. American Society for Nutrition
Background Lactation is a demanding period for women, and a good nutrition is crucial for optimal health of mothers and infants. Objectives To provide new data and summarize the overall evidence on maternal nutrient intakes during lactation in develo
Autor:
Küçükköse, Emre, Heesters, Balthasar A., Villaudy, Julien, Verheem, André, Cercel, Madalina, Van Hal, Susan, Boj, Sylvia F., Borel Rinkes, Inne H.M., Punt, Cornelis J.A., Roodhart, Jeanine M.L., Laoukili, Jamila, Koopman, Miriam, Spits, Hergen, Kranenburg, Onno, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
Publikováno v:
Journal for immunotherapy of cancer, 10(12):e005345. BioMed Central Ltd.
Journal for ImmunoTherapy of Cancer, 10(12). BioMed Central
Journal for ImmunoTherapy of Cancer, 10(12). BioMed Central
BackgroundThe immunogenic nature of metastatic colorectal cancer (CRC) with high microsatellite instability (MSI-H) underlies their responsiveness to immune checkpoint blockade (ICB). However, resistance to ICB is commonly observed, and is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e358bc49116a9c9b1170b08b25f8c92
https://dspace.library.uu.nl/handle/1874/426611
https://dspace.library.uu.nl/handle/1874/426611
Autor:
Slingerland, Cornelis J., Wesseling, Charlotte M. J., Innocenti, Paolo, Westphal, Koen G. C., Masereeuw, Rosalinde, Martin, Nathaniel I., Afd Chemical Biology and Drug Discovery, Afd Pharmacology, Chemical Biology and Drug Discovery, Pharmacology
Publikováno v:
Journal of Medicinal Chemistry. AMER CHEMICAL SOC
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 65(23), 15878-15892. American Chemical Society (ACS)
Journal of Medicinal Chemistry, 65(23). American Chemical Society : Division of Carbohydrate Chemistry
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 65(23), 15878-15892. American Chemical Society (ACS)
Journal of Medicinal Chemistry, 65(23). American Chemical Society : Division of Carbohydrate Chemistry
Polymyxins are a class of lipopeptide anti-infective agents with potent and specific activity against Gram-negative bacteria. While toxicity concerns associated with polymyxin B and E (colistin) have historically limited their clinical application, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b9e98a038752edb0c1e0999cf52137
https://dspace.library.uu.nl/handle/1874/424682
https://dspace.library.uu.nl/handle/1874/424682
Autor:
Mukherjee, Reshmi, Somovilla, Victor J., Chiodo, Fabrizio, Bruijns, Sven, Pieters, Roland J., Garssen, Johan, van Kooyk, Yvette, Kraneveld, Aletta D., van Bergenhenegouwen, Jeroen, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery
Publikováno v:
International Journal of Molecular Sciences, 23(23):14745. Multidisciplinary Digital Publishing Institute (MDPI)
Mukherjee, R, Somovilla, V J, Chiodo, F, Bruijns, S, Pieters, R J, Garssen, J, van Kooyk, Y, Kraneveld, A D & van Bergenhenegouwen, J 2022, ' Human Milk Oligosaccharide 2′-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin ', International Journal of Molecular Sciences, vol. 23, no. 23, 14745 . https://doi.org/10.3390/ijms232314745
International Journal of Molecular Sciences, 23(23). MDPI AG
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14745
Mukherjee, R, Somovilla, V J, Chiodo, F, Bruijns, S, Pieters, R J, Garssen, J, van Kooyk, Y, Kraneveld, A D & van Bergenhenegouwen, J 2022, ' Human Milk Oligosaccharide 2′-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin ', International Journal of Molecular Sciences, vol. 23, no. 23, 14745 . https://doi.org/10.3390/ijms232314745
International Journal of Molecular Sciences, 23(23). MDPI AG
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14745
Human milk oligosaccharides (HMOs) and its most abundant component, 2’-Fucosyllactose (2’-FL), are known to be immunomodulatory. Previously, it was shown that HMOs and 2’-FL bind to the C-type lectin receptor DC-SIGN. Here we show, using a liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397548f872e9d9634252e8ded71318d7
https://research.vumc.nl/en/publications/4865007f-5f57-4a72-991b-d0244eb99e28
https://research.vumc.nl/en/publications/4865007f-5f57-4a72-991b-d0244eb99e28