Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Afd Biomol.Mass Spect. and Proteomics"'
Autor:
Pongracz, Tamas, Vidarsson, Gestur, Wuhrer, Manfred, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Glycoconjugate Journal, 39, 335-344. Springer Science and Business Media {LLC}
Glycoconjugate Journal
Glycoconjugate Journal, 39(3). Springer Netherlands
Glycoconjugate Journal
Glycoconjugate Journal, 39(3). Springer Netherlands
Antibody glycosylation has received considerable attention in coronavirus disease 2019 (COVID-19) infections and recently also in vaccination. Antibody glycosylation and in particular immunoglobulin G1 fucosylation levels influence effector functions
Autor:
Subramaniam, Gunasekaran, Schleicher, Katharina, Kovanich, Duangnapa, Zerio, Anna, Folkmanaite, Milda, Chao, Ying-Chi, Surdo, Nicoletta C, Koschinski, Andreas, Hu, Jianshu, Scholten, Arjen, Heck, Albert J R, Ercu, Maria, Sholokh, Anastasiia, Chan Park, Kyung, Klussmann, Enno, Meraviglia, Viviana, Bellin, Milena, Zanivan, Sara, Hester, Svenja, Mohammed, Shabaz, Zaccolo, Manuela, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Circulation Research, 132(7), 828. Lippincott Williams and Wilkins
Background: Signaling by cAMP is organized in multiple distinct subcellular nanodomains regulated by cAMP-hydrolyzing PDEs (phosphodiesterases). Cardiac β-adrenergic signaling has served as the prototypical system to elucidate cAMP compartmentalizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be17dc69d08d51c3b787967a21803764
https://dspace.library.uu.nl/handle/1874/427606
https://dspace.library.uu.nl/handle/1874/427606
Autor:
Aguinagalde Salazar, Leire, den Boer, Maurits A, Castenmiller, Suzanne M, Zwarthoff, Seline A, de Haas, Carla, Aerts, Piet C, Beurskens, Frank J, Schuurman, Janine, Heck, Albert J R, van Kessel, Kok, Rooijakkers, Suzan H M, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
eLife, 12. eLife Sciences Publications
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and an important cause of childhood mortality. Despite the introduction of successful vaccines, the global spread of both non-vaccine serotypes and antibiotic-resistant str
Autor:
Hevler, Johannes F, Albanese, Pascal, Cabrera-Orefice, Alfredo, Potter, Alisa, Jankevics, Andris, Misic, Jelena, Scheltema, Richard A, Brandt, Ulrich, Arnold, Susanne, Heck, Albert J R, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Open Biology, 13
Open Biology, 13, 3
Open Biology, 13(3). The Royal Society
Open Biology, 13, 3
Open Biology, 13(3). The Royal Society
Contains fulltext : 290938.pdf (Publisher’s version ) (Open Access) The tricarboxylic acid cycle is the central pathway of energy production in eukaryotic cells and plays a key part in aerobic respiration throughout all kingdoms of life. One of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298c8ea46f2b0c933625e55149a752c3
https://dspace.library.uu.nl/handle/1874/427594
https://dspace.library.uu.nl/handle/1874/427594
Autor:
Lyu, Jun, Tegelaar, Martin, Post, Harm, Moran Torres, Juan, Torchia, Costanza, Altelaar, A F Maarten, Bleichrodt, Robert-Jan, de Cock, Hans, Lugones, Luis G, Wösten, Han A B, Molecular Microbiology, Biomolecular Mass Spectrometry and Proteomics, Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spect. and Proteomics
Publikováno v:
mBio, 14(1), 1. American Society for Microbiology
The fungus Aspergillus niger is among the most abundant fungi in the world and is widely used as a cell factory for protein and metabolite production. This fungus forms asexual spores called conidia that are used for dispersal. Notably, part of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e4b21da3b05924614431e61bf11d17
https://dspace.library.uu.nl/handle/1874/428131
https://dspace.library.uu.nl/handle/1874/428131
Autor:
Rees, Dieke J. van, Brinkhaus, Maximilian, Klein, Bart, Verkuijlen, Paul, Tool, Anton T.J., Schornagel, Karin, Treffers, Louise W., Houdt, Michel van, Kater, Arnon P., Vidarsson, Gestur, Gennery, Andrew R., Kuijpers, Taco W., Bruggen, Robin van, Matlung, Hanke L., Berg, Timo K. van den, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Blood advances, 6(7). American Society of Hematology
van Rees, D J, Brinkhaus, M, Klein, B, Verkuijlen, P, Tool, A T J, Schornagel, K, Treffers, L W, van Houdt, M, Kater, A P, Vidarsson, G, Gennery, A R, Kuijpers, T W, van Bruggen, R, Matlung, H L & van den Berg, T K 2022, ' Sodium stibogluconate and CD47-SIRPa blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing ', Blood, vol. 6, no. 7, pp. 2156-2166 . https://doi.org/10.1182/bloodadvances.2021005367
Blood advances, 6(7), 2156-2166. American Society of Hematology
Blood, 6(7), 2156-2166. American Society of Hematology
van Rees, D J, Brinkhaus, M, Klein, B, Verkuijlen, P, Tool, A T J, Schornagel, K, Treffers, L W, van Houdt, M, Kater, A P, Vidarsson, G, Gennery, A R, Kuijpers, T W, van Bruggen, R, Matlung, H L & van den Berg, T K 2022, ' Sodium stibogluconate and CD47-SIRPa blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing ', Blood, vol. 6, no. 7, pp. 2156-2166 . https://doi.org/10.1182/bloodadvances.2021005367
Blood advances, 6(7), 2156-2166. American Society of Hematology
Blood, 6(7), 2156-2166. American Society of Hematology
Anti-CD20 antibodies such as rituximab are broadly used to treat B-cell malignancies. These antibodies can induce various effector functions, including immune cell-mediated antibody-dependent cellular cytotoxicity (ADCC). Neutrophils can induce ADCC
Autor:
Cramer, Dario A T, Franc, Vojtech, Heidenreich, Anna-Katharina, Hook, Michaela, Adibzadeh, Mahdi, Reusch, Dietmar, Heck, Albert J R, Haberger, Markus, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
mAbs, 15(1), 1. Landes Bioscience
The development of increasingly complex antibody formats, such as bispecifics, can lead to the formation of increasingly complex high- and low-molecular-weight by-products. Here, we focus on the characterization of high molecular weight species (HMWs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee80fd2439cd2f667d2e1ccfff64760
https://dspace.library.uu.nl/handle/1874/427344
https://dspace.library.uu.nl/handle/1874/427344
Autor:
Chen, Yen-Hsi, Tian, Weihua, Yasuda, Makiko, Ye, Zilu, Song, Ming, Mandel, Ulla, Kristensen, Claus, Povolo, Lorenzo, Marques, André R A, Čaval, Tomislav, Heck, Albert J R, Sampaio, Julio Lopes, Johannes, Ludger, Tsukimura, Takahiro, Desnick, Robert, Vakhrushev, Sergey Y, Yang, Zhang, Clausen, Henrik, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Chen, Y-H, Tian, W, Yasuda, M, Ye, Z, Song, M, Mandel, U, Kristensen, C, Povolo, L, Marques, A R A, Čaval, T, Heck, A J R, Sampaio, J L, Johannes, L, Tsukimura, T, Desnick, R, Vakhrushev, S Y, Yang, Z & Clausen, H 2023, ' A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution ', Frontiers in Bioengineering and Biotechnology, vol. 11, 1128371 . https://doi.org/10.3389/fbioe.2023.1128371
Chen, Y H, Tian, W, Yasuda, M, Ye, Z, Song, M, Mandel, U, Kristensen, C, Povolo, L, Marques, A R A, Čaval, T, Heck, A J R, Sampaio, J L, Johannes, L, Tsukimura, T, Desnick, R, Vakhrushev, S Y, Yang, Z & Clausen, H 2023, ' A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution ', Frontiers in Bioengineering and Biotechnology, vol. 11, 1128371 . https://doi.org/10.3389/fbioe.2023.1128371
Frontiers in Bioengineering and Biotechnology, 11. Frontiers Media S.A.
Chen, Y H, Tian, W, Yasuda, M, Ye, Z, Song, M, Mandel, U, Kristensen, C, Povolo, L, Marques, A R A, Čaval, T, Heck, A J R, Sampaio, J L, Johannes, L, Tsukimura, T, Desnick, R, Vakhrushev, S Y, Yang, Z & Clausen, H 2023, ' A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution ', Frontiers in Bioengineering and Biotechnology, vol. 11, 1128371 . https://doi.org/10.3389/fbioe.2023.1128371
Frontiers in Bioengineering and Biotechnology, 11. Frontiers Media S.A.
Currently available enzyme replacement therapies for lysosomal storage diseases are limited in their effectiveness due in part to short circulation times and suboptimal biodistribution of the therapeutic enzymes. We previously engineered Chinese hams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61b98c4894e0c37b4a5abd40c25b07f
https://orbit.dtu.dk/en/publications/930ddf65-3230-48ba-b060-1fd963d4bb25
https://orbit.dtu.dk/en/publications/930ddf65-3230-48ba-b060-1fd963d4bb25
Autor:
Brinkkemper, Mitch, Veth, Tim S, Brouwer, Philip J M, Turner, Hannah, Poniman, Meliawati, Burger, Judith A, Bouhuijs, Joey H, Olijhoek, Wouter, Bontjer, Ilja, Snitselaar, Jonne L, Caniels, Tom G, van der Linden, Cynthia A, Ravichandran, Rashmi, Villaudy, Julien, van der Velden, Yme U, Sliepen, Kwinten, van Gils, Marit J, Ward, Andrew B, King, Neil P, Heck, Albert J R, Sanders, Rogier W, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
iScience, 25(12):105649. Elsevier Inc.
iScience, 25(12), 1. Elsevier
iScience, 25(12), 1. Elsevier
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants poses continuous challenges in combating the virus. Here, we describe vaccination strategies to broaden SARS-CoV-2 and sarbecovirus immunity by combining spike pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101628e2b49b1c3d2b6fc48dac0af246
https://doi.org/10.1016/j.isci.2022.105649
https://doi.org/10.1016/j.isci.2022.105649
Autor:
van der Grein, Susanne G, Defourny, Kyra A Y, Rabouw, Huib H, Goerdayal, Soenita S, van Herwijnen, Martijn J C, Wubbolts, Richard W, Altelaar, Maarten, van Kuppeveld, Frank J M, Nolte-'t Hoen, Esther N M, Virologie, Celbiologie, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research, IOV CCB
Publikováno v:
Nature Communications, 13(1), 1. Nature Publishing Group
Naked viruses can escape host cells before the induction of lysis via release in extracellular vesicles (EVs). These nanosized EVs cloak the secreted virus particles in a host-derived membrane, which alters virus-host interactions that affect infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715dc8fabcbab2da9136d6074e7e4801
https://dspace.library.uu.nl/handle/1874/421357
https://dspace.library.uu.nl/handle/1874/421357