Redox imbalance in COVID-19 pathophysiology.

Autor: Majumder N; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA., Deepak V; Department of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, West Virginia University, Morgantown, WV, USA., Hadique S; Department of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, West Virginia University, Morgantown, WV, USA., Aesoph D; WVU Cancer Institute, West Virginia University, Morgantown, WV, USA; Lane Department of Computer Science & Electrical Engineering, West Virginia University, Morgantown, WV, USA., Velayutham M; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA; Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV, USA., Ye Q; WVU Cancer Institute, West Virginia University, Morgantown, WV, USA; Lane Department of Computer Science & Electrical Engineering, West Virginia University, Morgantown, WV, USA., Mazumder MHH; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA., Lewis SE; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA., Kodali V; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA., Roohollahi A; Department of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, West Virginia University, Morgantown, WV, USA., Guo NL; WVU Cancer Institute, West Virginia University, Morgantown, WV, USA; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, Morgantown, WV, USA., Hu G; WVU Cancer Institute, West Virginia University, Morgantown, WV, USA; Department of Microbiology, Immunology & Cell Biology, West Virginia University, Morgantown, WV, USA., Khramtsov VV; Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV, USA., Johnson RJ; Department of Medicine, Division of Renal Diseases and Hypertension, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., Wen S; Department of Epidemiology and Biostatistics, West Virginia University, Morgantown, WV, USA., Kelley EE; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA., Hussain S; Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, WV, USA; Department of Microbiology, Immunology & Cell Biology, West Virginia University, Morgantown, WV, USA. Electronic address: salik.hussain@hsc.wvu.edu.

Publikováno v: Redox biology [Redox Biol] 2022 Oct; Vol. 56, pp. 102465. Date of Electronic Publication: 2022 Sep 11.

Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation.

Autor: Monaghan KL; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506., Aesoph D; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506.; Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, WV 26506., Ammer AG; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506.; Microscope Imaging Facility, West Virginia University, Morgantown, WV 26506., Zheng W; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506., Rahimpour S; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506., Farris BY; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506., Spinner CA; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892., Li P; Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892., Lin JX; Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892., Yu ZX; Pathology Core, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892., Lazarevic V; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892., Hu G; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506.; Bioinformatics Core, West Virginia University, Morgantown, WV 26506., Leonard WJ; Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892; wjl@helix.nih.gov edwin.wan@hsc.wvu.edu., Wan ECK; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506; wjl@helix.nih.gov edwin.wan@hsc.wvu.edu.; Department of Neuroscience, West Virginia University, Morgantown, WV 26506.; Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV 26506.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Dec 28; Vol. 118 (52).

XX sex chromosome complement modulates immune responses to heat-killed Streptococcus pneumoniae immunization in a microbiome-dependent manner.

Autor: Amato-Menker, Carly J.^1,2 (AUTHOR), Hopen, Quinn^1,2 (AUTHOR), Pettit, Andrea¹ (AUTHOR), Gandhi, Jasleen^1,3 (AUTHOR), Hu, Gangqing¹ (AUTHOR), Schafer, Rosana¹ (AUTHOR), Franko, Jennifer^1,2 (AUTHOR) jlfranko@hsc.wvu.edu

Publikováno v: Biology of Sex Differences. 3/14/2024, Vol. 15 Issue 1, p1-24. 24p.

Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling.

Autor: Wang, Lei¹ (AUTHOR) lei.wang1@hsc.wvu.edu, Yi, Weijun^1,2 (AUTHOR) donald.adjeroh@mail.wvu.edu, Ma, Li¹ (AUTHOR) li.ma@hsc.wvu.edu, Lecea, Emily¹ (AUTHOR) eel0009@mix.wvu.edu, Hazlehurst, Lori A.^3,4 (AUTHOR) lahazlehurst@hsc.wvu.edu, Adjeroh, Donald A.² (AUTHOR), Hu, Gangqing^1,3 (AUTHOR) michael.hu@hsc.wvu.edu

Publikováno v: Cancers. Nov2023, Vol. 15 Issue 21, p5148. 16p.

Endogenous glucocorticoids are required for normal macrophage activation and gastric Helicobacter pylori immunity.

Autor: Khadka, Stuti, Dziadowicz, Sebastian A., Xu, Xiaojiang, Wang, Lei, Hu, Gangqing, Carrero, Javier A., DiPaolo, Richard J., Busada, Jonathan T.

Publikováno v: American Journal of Physiology: Gastrointestinal & Liver Physiology; Oct2024, Vol. 327 Issue 4, pG531-G544, 14p