Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aeromonas/metabolism"'
Publikováno v:
Cell. 126:1135-1145
SummaryMany pathogenic organisms produce pore-forming toxins as virulence factors. Target cells however mount a response to such membrane damage. Here we show that toxin-induced membrane permeabilization leads to a decrease in cytoplasmic potassium,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd7ed334b99f2677c6df074027096b4
https://doi.org/10.1016/j.cell.2006.07.033
https://doi.org/10.1016/j.cell.2006.07.033
Autor:
Susanne C. Feil, S M Raja, Jamie Rossjohn, J T Buckley, Michael W. Parker, F. G. van der Goot, K L Nelson
Publikováno v:
Biochemistry, Vol. 37, No 2 (1998) pp. 741-746
Aerolysin is a channel-forming toxin that must oligomerize in order to become insertion-competent. Modeling based on the crystal structure of the proaerolysin dimer and electron microscopic images of the oligomer indicated that a loop in domain 3 mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab20845f1247e1de2cd4c660c2651f7c
https://doi.org/10.1021/bi9721039
https://doi.org/10.1021/bi9721039