Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aerobic glycolysi"'
Autor:
Maja Malnar, Angela Bachi, Helena H. Chowdhury, Anemari Horvat, Patrizia D’Adamo, Antonia Gurgone, Saša Trkov Bobnar, Marko Muhič, Lorenzo Piemonti, Maria Lidia Mignogna, Michela Masetti, Jelena Velebit, Veronica Bianchi, Robert Zorec, Matjaž Stenovec, Alessia Mercalli, Katja Fink, Sara Belloli, Stefano Taverna, Maja Potokar, Marko Kreft, Rosa Maria Moresco, Nina Vardjan, Maddalena Ripamonti, Umberto Restuccia
Publikováno v:
Metabolism
Metabolism, clinical and experimental
116 (2021): 154463. doi:10.1016/j.metabol.2020.154463
info:cnr-pdr/source/autori:D'Adamo P.; Horvat A.; Gurgone A.; Mignogna M.L.; Bianchi V.; Masetti M.; Ripamonti M.; Taverna S.; Velebit J.; Malnar M.; Muhic M.; Fink K.; Bachi A.; Restuccia U.; Belloli S.; Moresco R.M.; Mercalli A.; Piemonti L.; Potokar M.; Bobnar S.T.; Kreft M.; Chowdhury H.H.; Stenovec M.; Vardjan N.; Zorec R./titolo:Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse/doi:10.1016%2Fj.metabol.2020.154463/rivista:Metabolism, clinical and experimental (Print)/anno:2021/pagina_da:154463/pagina_a:/intervallo_pagine:154463/volume:116
Metabolism, clinical and experimental
116 (2021): 154463. doi:10.1016/j.metabol.2020.154463
info:cnr-pdr/source/autori:D'Adamo P.; Horvat A.; Gurgone A.; Mignogna M.L.; Bianchi V.; Masetti M.; Ripamonti M.; Taverna S.; Velebit J.; Malnar M.; Muhic M.; Fink K.; Bachi A.; Restuccia U.; Belloli S.; Moresco R.M.; Mercalli A.; Piemonti L.; Potokar M.; Bobnar S.T.; Kreft M.; Chowdhury H.H.; Stenovec M.; Vardjan N.; Zorec R./titolo:Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse/doi:10.1016%2Fj.metabol.2020.154463/rivista:Metabolism, clinical and experimental (Print)/anno:2021/pagina_da:154463/pagina_a:/intervallo_pagine:154463/volume:116
Objectives GDI1 gene encodes for αGDI, a protein controlling the cycling of small GTPases, reputed to orchestrate vesicle trafficking. Mutations in human GDI1 are responsible for intellectual disability (ID). In mice with ablated Gdi1, a model of ID
Autor:
Paolo Ascenzi, Nélida I. Noguera, Jacopo Albanesi, Stefano Leone, Cristina Banella, Fabrizio Bianchi, Elisabetta De Marinis, Orazio Palumbo, Maria Teresa Voso, Alessandra di Masi, Tommaso Colangelo, Clara Nervi
Publikováno v:
Cells, Vol 9, Iss 2423, p 2423 (2020)
Cells
Volume 9
Issue 11
Cells
Volume 9
Issue 11
Acute promyelocytic leukemia (APL) is a hematological disease characterized by a balanced reciprocal translocation that leads to the synthesis of the oncogenic fusion protein PML-RAR&alpha
APL is mainly managed by a differentiation therapy based
APL is mainly managed by a differentiation therapy based
Autor:
Stefano Mazzoleni, Jacinta Serpa, Palma Parascandola, Elisabetta de Alteriis, Fabrizio Cartenì
Publikováno v:
Cell Cycle
The mechanisms behind the Warburg effect in mammalian cells, as well as for the similar Crabtree effect in the yeast Saccharomyces cerevisiae, are still a matter of debate: why do cells shift from the energy-efficient respiration to the energy-ineffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf22201019ade100ef110a0c2baeeceb
http://hdl.handle.net/11588/712861
http://hdl.handle.net/11588/712861
Autor:
Luigi Fiume, Marinella Roberti, Marcella Manerba, Giuseppina Di Stefano, Lorenza Di Ianni, Maurizio Recanatini
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 74
Up-regulation of glycolysis, a well recognized hallmark of cancer cells, was also found to be predictive of poor chemotherapy response. This observation suggested the attempt of sensitizing cancer cells to conventional chemotherapeutic agents by inhi
Autor:
Annamaria Spina, Luigi Sapio, Monica Gallo, Armando Calogero, Daniele Naviglio, Silvio Naviglio
Publikováno v:
Scopus-Elsevier
Despite the intense scientific efforts made, there are still many tumors that are difficult to treat and the percentage of patient survival in the long-term is still too low. Thus, new approaches to the treatment of cancer are needed. Cancer is a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12803d19b7757fc363923e5bddf0d28a
http://hdl.handle.net/11591/195777
http://hdl.handle.net/11591/195777
Autor:
Nadine Lukan, Rainer Grobholz, A Steidler, Johannes F. Coy, Sigrun Langbein, Peter Alken, K Rensch-Boschert, J. Popa, Frank Willeke, Wilko Staiger, Christel Weiss, Monica Zerilli, P. Schubert, Giorgio Stassi, A. zur Hausen, M P Ternullo
Publikováno v:
British Journal of Cancer
Tumours ferment glucose to lactate even in the presence of oxygen (aerobic glycolysis; Warburg effect). The pentose phosphate pathway (PPP) allows glucose conversion to ribose for nucleic acid synthesis and glucose degradation to lactate. The nonoxid