Zobrazeno 1 - 10
of 5 838
pro vyhledávání: '"Aerobic Glycolysis"'
Autor:
Chenxi Zeng, Huihui Yue, Congjian Wang, Xuetao Ju, Tianlai Wang, Xiangning Fu, Qing Zhou, Huilan Zhang, Long He, Jun Yu, Yi Wang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal lung disorder for which effective treatments remain limited. Recent investigations revealed a potential link between altered glucose metabolism and the activation of fibr
Externí odkaz:
https://doaj.org/article/3a1735358082481e9f6a1430dedfa1fe
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4497-4510 (2024)
Anni Zhao,1,* Xiaomei Liu,1,* Xiping Chen,1,* Sha Na,1,* Hui Wang,1 Xuan Peng,1 Peizhong Kong,1 Lu Li1,2 1Department of Biochemistry and Molecular Biology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese
Externí odkaz:
https://doaj.org/article/e4fe099d9f1348c78b426412194afce3
Autor:
Katsuya Sakimura, Takashi Kawai, Reiko Nashida, Yuji Ishida, Kana Harada, Takashi Suzuki, Chihiro Okuma, Gregory M. Cole
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer’s disease (AD) is the most common form of dementia. Although drugs focusing on reducing amyloid β slow progression, they fail to improve cognitive function. Deficits in glucose metabolism are reflected in FDG-PET and
Externí odkaz:
https://doaj.org/article/d0cd1b22ce1843a987fdf8ace4913d23
Autor:
Ayoola O. Ogunleye, Neelanjana Gayen, Sanchita Rauth, Saravanakumar Marimuthu, Rama Krishna Nimmakayala, Zahraa W. Alsafwani, Jesse L. Cox, Surinder K. Batra, Moorthy P. Ponnusamy
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background PAF1/PD2 deregulation contributes to tumorigenesis, drug resistance, and cancer stem cell maintenance in Pancreatic Cancer (PC). Recent studies demonstrate that metabolic reprogramming plays a role in PC progression, but the mecha
Externí odkaz:
https://doaj.org/article/3ef116e6ac1745ca95ccd797415b56f9
Autor:
Yang Chen, Mingchao Zhang, Ruoyu Jia, Bin Qian, Chenyang Jing, Caihong Zeng, Dihan Zhu, Zhihong Liu, Ke Zen, Limin Li
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103439- (2024)
Podocyte injury is a critical event in the pathogenesis of diabetic nephropathy (DN). Hyperglycemia, oxidative stress, inflammation, and other factors contribute to podocyte damage in DN. In this study, we demonstrate that signaling regulatory protei
Externí odkaz:
https://doaj.org/article/9c5c3be4dd4845b185b78a472c2fe629
Autor:
Justin B. Collier, Hong Soon Kang, Yun-Gil Roh, Chitrangda Srivastava, Sara A. Grimm, Alan K. Jarmusch, Anton M. Jetten
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102052- (2024)
Objectives: Deficiency in the transcription factor (TF) GLI-Similar 3 (GLIS3) in humans and mice leads to the development of polycystic kidney disease (PKD). In this study, we investigate the role of GLIS3 in the regulation of energy metabolism and m
Externí odkaz:
https://doaj.org/article/a8e70fb81db8452f9739f621caf1bb2c
Autor:
Adriana Fernanda K. Vizuete, Fernanda Fróes, Marina Seady, Aline Castro Caurio, Osmar Vieira Ramires Junior, Ana Karla Oliveira Leite, Clarissa Penha Farias, Angela T.S. Wyse, Carlos-Alberto Gonçalves
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100901- (2024)
Neuroinflammation is a pathophysiological feature of numerous neurological and psychiatric disorders. The immune response in the central nervous system, driven by microglia and astrocytes, leads to metabolic reprogramming towards aerobic glycolysis,
Externí odkaz:
https://doaj.org/article/f8f18099a58a4c3998bb1f87d10e87c0
Autor:
Rong Qin, Xirui Fan, Yun Huang, Sijing Chen, Rui Ding, Ying Yao, Rui Wu, Yiyao Duan, Xiang Li, Hameed Ullah Khan, Jun Hu, Hui Wang
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102156- (2024)
Colorectal cancer (CRC), with the incidence and mortality rising on a yearly basis, greatly threatens people's health. It is considered an important hallmark of tumorigenesis that aberrant glucose metabolism in cancer cells, particularly the Warburg
Externí odkaz:
https://doaj.org/article/8ea334f57b25479cbc3b4de1467ddcf4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEnergy metabolism abnormity emerges as a crucial factor that facilitates tumorigenesis by accelerating aerobic glycolysis. However, the function of N6-methyladenosine (m6A) on hepatocellular carcinoma (HCC) aerobic glycolysis and immune e
Externí odkaz:
https://doaj.org/article/bd939816c1d54f88a871a3af9bf58843
Autor:
Mücahit Varlı, Eunae Kim, Songjin Oh, Sultan Pulat, Rui Zhou, Chathurika D. B. Gamage, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man-Jeong Paik, Hangun Kim
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Expression of the KITENIN/ErbB4 oncogenic complex is associated with metastasis of colorectal cancer to distant organs and lymph nodes and is linked with poor prognosis and poor survival. Methods Here, we used in vitro and in sili
Externí odkaz:
https://doaj.org/article/bb5af59f1fc94f018424f9e8a5739fc7