Recurrent Stroke in a Young Patient with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Quo Vadis?

Autor: Katharina Feil, Johanna Heinrich, Aenne S. von Falkenhausen, Regina Becker, Clemens Küpper, Katharina Müller, Dennis C. Thunstedt, Moritz F. Sinner, Stefan Kääb, Lars Kellert

Publikováno v: Case Reports in Neurology, Vol 12, Iss 1, Pp 45-49 (2020)

So far, there has been no generally accepted diagnostic and therapeutic algorithm for patients with embolic stroke of undetermined source (ESUS). As recent clinical trials on secondary stroke prevention in ESUS did not support the use of oral anticoa

Externí odkaz: https://doaj.org/article/c68717d6aa5c43ba93e0479e21c837a9

Common electrocardiogram measures are not associated with telomere length

Autor: Aenne S. von Falkenhausen, Rebecca Freudling, Melanie Waldenberger, Christian Gieger, Annette Peters, Martina Müller-Nurasyid, Stefan Kääb, Moritz F. Sinner

Publikováno v: Aging 14, 5620-5627 (2022)

AIMS: Aging is accompanied by telomere shortening. Increased telomere shortening is considered a marker of premature aging. Cardiac aging results in the development of cardiac pathologies. Electrocardiogram (ECG) measures reflect cardiac excitation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ddadbde19395a07ee82074c7c35551
https://doi.org/10.18632/aging.204149

Rhythmusmonitoring

Autor: Moritz F. Sinner, Stefan Kääb, Aenne S von Falkenhausen, Stephanie Fichtner

Publikováno v: Herzschrittmachertherapie + Elektrophysiologie. 31:241-245

Cardiac rhythm monitoring plays an integral role in the diagnosis and treatment of various conditions. Technological developments of recent years have partly increased the ease of use and the availability of cardiac rhythm monitoring. Yet, the multit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::353bf70228914c3633679cdbf5fdc4be
https://doi.org/10.1007/s00399-020-00706-7

Clonal hematopoiesis is driven by aberrant activation of TCL1A

Autor: Joshua S. Weinstock, Jayakrishnan Gopakumar, Bala Bharathi Burugula, Md Mesbah Uddin, Nikolaus Jahn, Julia A. Belk, Bence Daniel, Nghi Ly, Taralyn M. Mack, Cecelia A. Laurie, Jai G. Broome, Kent D. Taylor, Xiuqing Guo, Moritz F. Sinner, Aenne S. von Falkenhausen, Stefan Kääb, Alan R. Shuldiner, Jeffrey R. O’Connell, Joshua P. Lewis, Eric Boerwinkle, Kathleen C. Barnes, Nathalie Chami, Eimear E. Kenny, Ruth J. Loos, Myriam Fornage, Lifang Hou, Donald M. Lloyd-Jones, Susan Redline, Brian E. Cade, Bruce M. Psaty, Joshua C. Bis, Jennifer A. Brody, Edwin K. Silverman, Jeong H. Yun, Dandi Qiao, Nicholette D. Palmer, Barry I. Freedman, Donald W. Bowden, Michael H. Cho, Dawn L. DeMeo, Ramachandran S. Vasan, Lisa R. Yanek, Lewis C. Becker, Sharon Kardia, Patricia A. Peyser, Jiang He, Michiel Rienstra, Pim Van der Harst, Robert Kaplan, Susan R. Heckbert, Nicholas L. Smith, Kerri L. Wiggins, Donna K. Arnett, Marguerite R. Irvin, Hemant Tiwari, Michael J. Cutler, Stacey Knight, J Brent. Muhlestein, Adolfo Correa, Laura M. Raffield, Yan Gao, Mariza de Andrade, Jerome I. Rotter, Stephen S. Rich, Russell P. Tracy, Barbara A. Konkle, Jill M. Johnsen, Marsha M. Wheeler, J. Gustav Smith, Olle Melander, Peter M. Nilsson, Brian S. Custer, Ravindranath Duggirala, Joanne E. Curran, John Blangero, Stephen McGarvey, L. Keoki Williams, Shujie Xiao, Mao Yang, C. Charles. Gu, Yii-Der Ida. Chen, Wen-Jane Lee, Gregory M. Marcus, John P. Kane, Clive R. Pullinger, M. Benjamin Shoemaker, Dawood Darbar, Dan Roden, Christine Albert, Charles Kooperberg, Ying Zhou, JoAnn E. Manson, Pinkal Desai, Andrew Johnson, Rasika Mathias, Thomas W. Blackwell, Goncalo R. Abecasis, Albert V. Smith, Hyun M. Kang, Ansuman T. Satpathy, Pradeep Natarajan, Jacob Kitzman, Eric Whitsel, Alexander P. Reiner, Alexander G. Bick, Sidd Jaiswal

A diverse set of driver genes, such as regulators of DNA methylation, RNA splicing, and chromatin remodeling, have been associated with pre-malignant clonal expansion of hematopoietic stem cells (HSCs). The factors mediating expansion of these mutant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c2602e34829067c8289a05cb0696895
https://doi.org/10.1101/2021.12.10.471810

Catch-up-ESUS - follow-up in embolic stroke of undetermined source (ESUS) in a prospective, open-label, observational study: study protocol and initial baseline data

Autor: Moritz F. Sinner, Katharina Feil, Lars Kellert, Christoph Laub, Johanna Heinrich, Katharina Müller, Regina Becker, Frank A. Wollenweber, Clemens Küpper, Stefan Kääb, Aenne S von Falkenhausen

Publikováno v: BMJ Open

IntroductionSo far there is no uniform, commonly accepted diagnostic and therapeutic algorithm for patients with embolic stroke of undetermined source (ESUS). Recent clinical trials on secondary stroke prevention in ESUS did not support the use of or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b9a3f8cfc61d4ee14f3c28525ef2de
https://opus.bibliothek.uni-augsburg.de/opus4/files/93014/e031716.full.pdf