Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Aekkachai Puseenam"'
Autor:
Worarat Kruasuwan, Aekkachai Puseenam, Chitwadee Phithakrotchanakoon, Sutipa Tanapongpipat, Niran Roongsawang
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0258005 (2021)
The thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC 656 is a potential host strain for industrial protein production. Heterologous proteins are often retained intracellularly in yeast resulting in endoplasmic reticulum (ER) stress
Externí odkaz:
https://doaj.org/article/2f0d6faccf15452a96ffe9e6c7669445
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261754 (2021)
CRISPR multiplex gRNA systems have been employed in genome engineering in various industrially relevant yeast species. The thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC 656 is an alternative host for heterologous protein producti
Externí odkaz:
https://doaj.org/article/ef9a6d6c4b71416d9e1a1c7f3adfb24d
Autor:
Jirakrit Saetang, Aekkachai Puseenam, Niran Roongsawang, Supayang Piyawan Voravuthikunchai, Surasak Sangkhathat, Varomyalin Tipmanee
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160321 (2016)
In recent years, cytokine-mediated therapy has emerged as further advance alternative in cancer therapy. Interleukin-18 (IL-18) has exhibited interesting anti-cancer properties especially when combined with IL-12. We engineered IL-18 in order to impr
Externí odkaz:
https://doaj.org/article/4df9712e4e2043ee8a8a9c857c58862d
Autor:
Worarat Kruasuwan, Aekkachai Puseenam, Somjit Am-in, Srisakul Trakarnpaiboon, Warasirin Sornlek, Kanokarn Kocharin, Sasitorn Jindamorakot, Sutipa Tanapongpipat, Feng-Yan Bai, Niran Roongsawang
Publikováno v:
3 Biotech. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f305dab147af4194da863fb45b44bb8e
https://doi.org/10.1007/s13205-022-03436-4
https://doi.org/10.1007/s13205-022-03436-4
Autor:
Aekkachai Puseenam, Niran Roongsawang, Chitwadee Phithakrotchanakoon, Sutipa Tanapongpipat, Narumon Phaonakrop, Worarat Kruasuwan, Somsak Likhitrattanapisal, Sittiruk Roytrakul, Supawadee Ingsriswang
Publikováno v:
Yeast. 38:316-325
The thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC656 is a potential host for heterologous protein production. However, overproduction of heterologous protein can induce cellular stress and limit the level of its secretion. To imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95615da5934926b6b860eb6f846e3da6
https://doi.org/10.1002/yea.3548
https://doi.org/10.1002/yea.3548
Autor:
Chitwadee Phithakrotchanakoon, Niran Roongsawang, Sutipa Tanapongpipat, Narumon Phaonakrop, Aekkachai Puseenam, Sittiruk Roytrakul
Publikováno v:
Molecular Biology Reports. 45:1311-1319
In yeast, the accumulation of unfolded proteins in the ER triggers the unfolded protein response (UPR) pathway, which is mediated by Hac1 transcription factor. Here, we characterized the function of a gene encoding Hac1 in the thermotolerant methylot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2402c02bf69aa628ad489c056b48161
https://doi.org/10.1007/s11033-018-4287-4
https://doi.org/10.1007/s11033-018-4287-4
Autor:
Sutipa Tanapongpipat, Chitwadee Phithakrotchanakoon, Niran Roongsawang, Aekkachai Puseenam, Worarat Kruasuwan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0258005 (2021)
PLoS ONE, Vol 16, Iss 9, p e0258005 (2021)
The thermotolerant methylotrophic yeastOgataea thermomethanolicaTBRC 656 is a potential host strain for industrial protein production. Heterologous proteins are often retained intracellularly in yeast resulting in endoplasmic reticulum (ER) stress an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1dcef4e874304e70727e3440f98c53
https://doi.org/10.1371/journal.pone.0258005
https://doi.org/10.1371/journal.pone.0258005
Publikováno v:
BioEnergy Research. 10:891-902
This study presents an integrative design of experiment (intDoE) methodology for process optimization using a combination of experimental design, process flowsheet simulation, and economic model. This multilayered framework was implemented to simulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b906f8eb2df8775f5c124774f6a1000b
https://doi.org/10.1007/s12155-017-9851-6
https://doi.org/10.1007/s12155-017-9851-6
Autor:
Niran Roongsawang, Sutipa Tanapongpipat, Kriengsak Boonchoo, Aekkachai Puseenam, Kanokarn Kocharin
Publikováno v:
FEMS Microbiology Letters. 366
In this study, production of fungal phytase in thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC656 employing methanol-inducible OtAOX promoter and sucrose-inducible OtMal promoter was investigated in a high cell density fed-batch fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa525cf48749f8f0176a4f39936187c
https://doi.org/10.1093/femsle/fnz052
https://doi.org/10.1093/femsle/fnz052
Autor:
Niran Roongsawang, Kanokarn Kocharin, Aekkachai Puseenam, Supawadee Ingsriswang, Lily Eurwilaichitr, Sutipa Tanapongpipat
Publikováno v:
FEMS Microbiology Letters. 365
The thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC656 is a potential host for heterologous protein expression. In this study, a novel expression system was developed for O. thermomethanolica based on the maltase (mal) gene promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3138ef8abb0f63cd9bcf448eb7397045
https://doi.org/10.1093/femsle/fny238
https://doi.org/10.1093/femsle/fny238