Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Aejazur Rahman"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86886 (2014)
Mycobacterium tuberculosis (M.tb) has evolved mechanisms to evade its destruction in phagolysosomes, where it successfully survives and replicates within phagocytes. Recent studies have shown that virulent strains of M.tb can translocate from the pha
Externí odkaz:
https://doaj.org/article/6387b44023274cb3974a9713d6d23799
Autor:
Saumya S Srivastava, Satyabrata Pany, Amita Sneh, Neesar Ahmed, Aejazur Rahman, Krishnasastry V Musti
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6293 (2009)
BackgroundWild type Staphylococcal alpha-hemolysin (alpha-HL) assembly on target mammalian cells usually results in necrotic form of cell death; however, caspase activation also occurs. The pathways of caspase activation due to binding/partial assemb
Externí odkaz:
https://doaj.org/article/a47a6a8880ae4da0be153eea14ba6d5e
Autor:
Tafara T. R. Kunota, Md. Aejazur Rahman, Barry E. Truebody, Jared S. Mackenzie, Vikram Saini, Dirk A. Lamprecht, John H. Adamson, Ritesh R. Sevalkar, Jack R. Lancaster, Michael Berney, Joel N. Glasgow, Adrie J. C. Steyn
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1285 (2021)
H2S is a potent gasotransmitter in eukaryotes and bacteria. Host-derived H2S has been shown to profoundly alter M. tuberculosis (Mtb) energy metabolism and growth. However, compelling evidence for endogenous production of H2S and its role in Mtb phys
Externí odkaz:
https://doaj.org/article/fec3048b30624ab090468cbae2579f5b
Autor:
Bridgette M Cumming, Md Aejazur Rahman, Dirk A Lamprecht, Kyle H Rohde, Vikram Saini, John H Adamson, David G Russell, Adrie J C Steyn
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006490 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1006389.].
Externí odkaz:
https://doaj.org/article/32330ee4275c4525aff1402a66f64a54
Autor:
Bridgette M Cumming, Md Aejazur Rahman, Dirk A Lamprecht, Kyle H Rohde, Vikram Saini, John H Adamson, David G Russell, Adrie J C Steyn
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006389 (2017)
Signals modulating the production of Mycobacterium tuberculosis (Mtb) virulence factors essential for establishing long-term persistent infection are unknown. The WhiB3 redox regulator is known to regulate the production of Mtb virulence factors, how
Externí odkaz:
https://doaj.org/article/bbe88887c055490abf4056eb3e684a74
Autor:
Rui Wang, Shannon L. Russell, Kievershen Nargan, Pratistadevi K. Ramdial, John H. Adamson, Adrie J. C. Steyn, Bridgette M. Cumming, Aejazur Rahman, Hayden T Pacl, Threnesan Naidoo, Kelvin W. Addicott
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tuberculosis (TB) is responsible for millions of deaths each year and several billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb modulates host factors, such as endogenous gaseous signalling molecules, to per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ffb8f73d63d5b203fcfa9931e8d7cb
https://doi.org/10.1073/pnas.1919211117
https://doi.org/10.1073/pnas.1919211117
Autor:
Asaf Stein, Jack R. Lancaster, Tafara T.R. Kunota, Shannon M. Bailey, Jared S. Mackenzie, Dirk A. Lamprecht, Adrie J. C. Steyn, Vineel P. Reddy, Krishna C. Chinta, Vikram Saini, Barry E. Truebody, Douglas R. Moellering, Md. Aejazur Rahman, John H. Adamson, Joel N. Glasgow
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Hydrogen sulfide (H2S) is involved in numerous pathophysiological processes and shares overlapping functions with CO and •NO. However, the importance of host-derived H2S in microbial pathogenesis is unknown. Here we show that Mtb-infected mice defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa427814c223c5b5ff6ca38726388540
https://doaj.org/article/20fabbdfe15b499283f6565afa5077d3
https://doaj.org/article/20fabbdfe15b499283f6565afa5077d3
Autor:
Vikram Saini, Jared S. Mackenzie, Michael Berney, Md. Aejazur Rahman, Ritesh R. Sevalkar, Barry E. Truebody, John H. Adamson, Joel N. Glasgow, Jack R. Lancaster, Dirk A. Lamprecht, Tafara T.R. Kunota, Adrie J. C. Steyn
H2S is a potent gasotransmitter in eukaryotes and bacteria. Host-derived H2S has been shown to profoundly alter M. tuberculosis (Mtb) energy metabolism and growth. However, compelling evidence for endogenous production of H2S and its role in Mtb phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83078bac349cca4be8f4514dcde0b9a7
https://doi.org/10.1101/2021.06.02.446746
https://doi.org/10.1101/2021.06.02.446746
Autor:
Md. Aejazur Rahman, Joel N. Glasgow, Sajid Nadeem, Vineel P. Reddy, Ritesh R. Sevalkar, Jack R. Lancaster, Adrie J. C. Steyn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
For centuries, hydrogen sulfide (H2S) was considered primarily as a poisonous gas and environmental hazard. However, with the discovery of prokaryotic and eukaryotic enzymes for H2S production, breakdown, and utilization, H2S has emerged as an import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcc43ef485a974331be0f8b0fbb03e8
https://www.frontiersin.org/articles/10.3389/fcimb.2020.586923/full
https://www.frontiersin.org/articles/10.3389/fcimb.2020.586923/full
Autor:
Vikram Saini, Joel N. Glasgow, Jack R. Lancaster, Krishna C. Chinta, James H. Mazorodze, Darshan Reddy, Md. Aejazur Rahman, Adrie J. C. Steyn
Publikováno v:
Nitric Oxide. 59:28-41
Mycobacterium tuberculosis (Mtb) is a facultative intracellular pathogen and the second largest contributor to global mortality caused by an infectious agent after HIV. In infected host cells, Mtb is faced with a harsh intracellular environment inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceea2150a94f2f16d55fd70326403b6
https://doi.org/10.1016/j.niox.2016.06.009
https://doi.org/10.1016/j.niox.2016.06.009