Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Aedin Culhane"'
Autor:
Stefan Bentink, Benjamin Haibe-Kains, Thomas Risch, Jian-Bing Fan, Michelle S Hirsch, Kristina Holton, Renee Rubio, Craig April, Jing Chen, Eliza Wickham-Garcia, Joyce Liu, Aedin Culhane, Ronny Drapkin, John Quackenbush, Ursula A Matulonis
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30269 (2012)
Ovarian cancer is the fifth leading cause of cancer death for women in the U.S. and the seventh most fatal worldwide. Although ovarian cancer is notable for its initial sensitivity to platinum-based therapies, the vast majority of patients eventually
Externí odkaz:
https://doaj.org/article/882777890708423181fff7a4cf12a1ab
Autor:
Panagiotis A Konstantinopoulos, Stephen A Cannistra, Helen Fountzilas, Aedin Culhane, Kamana Pillay, Bo Rueda, Daniel Cramer, Michael Seiden, Michael Birrer, George Coukos, Lin Zhang, John Quackenbush, Dimitrios Spentzos
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18202 (2011)
Public data integration may help overcome challenges in clinical implementation of microarray profiles. We integrated several ovarian cancer datasets to identify a reproducible predictor of survival.Four microarray datasets from different institution
Externí odkaz:
https://doaj.org/article/1e24293bce8f4b34af46654c9fb21952
Autor:
Thomas W Chittenden, Jane Pak, Renee Rubio, Hailing Cheng, Kristina Holton, Niall Prendergast, Vladimir Glinskii, Yi Cai, Aedin Culhane, Stefan Bentink, Mathew Schwede, Jessica C Mar, Eleanor A Howe, Martin Aryee, Razvan Sultana, Anthony A Lanahan, Jennifer M Taylor, Chris Holmes, William C Hahn, Jean J Zhao, J Dirk Iglehart, John Quackenbush
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15581 (2010)
GIPC1 is a cytoplasmic scaffold protein that interacts with numerous receptor signaling complexes, and emerging evidence suggests that it plays a role in tumorigenesis. GIPC1 is highly expressed in a number of human malignancies, including breast, ov
Externí odkaz:
https://doaj.org/article/6d1b85371e1d4a2e868189e325035379
Autor:
Powel Brown, Jenny Chang, Susan Hilsenbeck, John Quackenbush, Aedin Culhane, Carolina Gutierrez, Ashley M. Herrick, Krystal Sexton, Anna Tsimelzon, Corey Speers
Supplementary Data from Identification of Novel Kinase Targets for the Treatment of Estrogen Receptor–Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6840795f18a350149ed4fddd2e4b9227
https://doi.org/10.1158/1078-0432.22439512
https://doi.org/10.1158/1078-0432.22439512
Autor:
Powel Brown, Jenny Chang, Susan Hilsenbeck, John Quackenbush, Aedin Culhane, Carolina Gutierrez, Ashley M. Herrick, Krystal Sexton, Anna Tsimelzon, Corey Speers
Purpose: Previous gene expression profiling studies of breast cancer have focused on the entire genome to identify genes differentially expressed between estrogen receptor (ER) α–positive and ER-α–negative cancers.Experimental Design: Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1567a65a1028ccf6d25b4838fbf76ae7
https://doi.org/10.1158/1078-0432.c.6516967
https://doi.org/10.1158/1078-0432.c.6516967
Autor:
Powel Brown, Jenny Chang, Susan Hilsenbeck, John Quackenbush, Aedin Culhane, Carolina Gutierrez, Ashley M. Herrick, Krystal Sexton, Anna Tsimelzon, Corey Speers
CCR Translation for the Article from Identification of Novel Kinase Targets for the Treatment of Estrogen Receptor–Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7294a06f17d14bc29f9d60b28dad07f6
https://doi.org/10.1158/1078-0432.22439515.v1
https://doi.org/10.1158/1078-0432.22439515.v1
Autor:
Matthew Pugh, Éanna Fennell, Ciara I Leahy, Tracey Perry, Beata Hargitai, Tamas Marton, Kelly J. Hunter, Graham Halford, Hale Onder Yilmaz, Zania Stamataki, Gary Reynolds, Harriet J. Hill, Benjamin E. Willcox, Neil Steven, Catherine A. Thornton, Stefan D. Dojcinov, Aedin Culhane, Paul G. Murray, Graham S. Taylor
SummaryCOVID-19 placentitis, a rare complication of maternal SARS-CoV-2 infection, only shows detectable virus in the placenta of a subset of cases. We provide a deep multi-omic spatial characterisation of placentitis from obstetrically complicated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4822eededef43f7b70e85cab464994
https://doi.org/10.1101/2022.11.14.516398
https://doi.org/10.1101/2022.11.14.516398
Autor:
Yufei Wang, Alicia Buck, Michael Lynch, Gabriella Kastrunes, Jae-Won Cho, Marion Grimaud, David Braun, Cecile Razimbaud, Matthew Chang, Atef Fayed, Audrey Apollon, Ze-Hua Li, Luann Zerefa, Brandon Piel, Elena Ivanova, Dennis Bonal, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Rebecca Jennings, Miriam Ficial, Maura Aliezah Sticco-Ivins, Sabina Signoretti, Catherine Wu, Toni Choueiri, Jon Wee, Cloud Paweletz, Martin Hemberg, Aedin Culhane, David Barbie, Gordon Freeman, Wayne Marasco
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Yufei Wang, Alicia Buck, Marion Grimaud, Aedin Culhane, David Braun, Sreekumar Kodangattil, Cecile Razimbaud, Matthew Chang, Atef Fayed, Audrey Apollon, Gabriella Kastrunes, Luann Zerefa, Brandon Piel, Elena Ivanova, Dennis Bonal, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Nicholas Hayden, Madison O'Donnell, Ying Huang, Rebecca Jenning, Miriam Ficial, Maura Aliezah Sticco-Ivins, Sabina Signoretti, Catherine Wu, Toni Choueiri, Jon Wee, Cloud Paweletz, David A. Barbie, Gordon Freeman, Wayne A. Marasco
Publikováno v:
Cancer Research. 82:2814-2814
Chimeric Antigen Receptor (CAR) T cell therapy is a new type of “living drug” that has proven to be a powerful, clinically translatable immunotherapy for hematologic malignancies. To date, there are five CAR-T products approved by FDA, four CD19
Autor:
Vincent J. Carey, Christophe Vanderaa, Davide Risso, Laurent Gatto, Marcel Ramos, Ludwig Geistlinger, Martin Morgan, Aedin Culhane, Levi Waldron, Ricard Argelaguet, Dario Righelli, Kelly Eckenrode
Publikováno v:
bioRxiv, Vol., no., p. (2021)
Background The majority of high-throughput single-cell molecular profiling methods quantify RNA expression; however, recent multimodal profiling methods add simultaneous measurement of genomic, proteomic, epigenetic, and/or spatial information on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ffa784e65052a81209ef1eb81ab692
https://hdl.handle.net/2078.1/258393
https://hdl.handle.net/2078.1/258393