Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Aedín C Culhane"'
Autor:
Matthew Schwede, Dimitrios Spentzos, Stefan Bentink, Oliver Hofmann, Benjamin Haibe-Kains, David Harrington, John Quackenbush, Aedín C Culhane
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57799 (2013)
Although ovarian cancer is often initially chemotherapy-sensitive, the vast majority of tumors eventually relapse and patients die of increasingly aggressive disease. Cancer stem cells are believed to have properties that allow them to survive therap
Externí odkaz:
https://doaj.org/article/3ab1014472544bf6b4ab08bcf4ea89cb
Autor:
Ursula A. Matulonis, David D.L. Bowtell, J. Dirk Iglehart, Ross S. Berkowitz, John Quackenbush, Anna DeFazio, Gillian Mitchell, Helga B. Salvesen, Alexander Miron, Dariush Etemadmoghadam, Joyce Liu, Huiying Piao, Kathryn E. Daniels, Kathryn Alsop, Matthew Schwede, Ruiyang Tian, Aquila Fatima, Ronny Drapkin, Aedín C. Culhane, Nicolai Juul Birkbak, Zhigang C. Wang
PDF file, 80K, Supplementary Tables 4-8: 4. LOH patterns in three cohorts, 5A&B. FLOH and chemotherapy resistance in three cohorts, 6. BRCA mutations in the AOCS, 7. Univariate and multivariate analysis of platinum resistantce, 8. PFS in LOH subclust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532079b01b3b7a8f301f1de6ee3674ff
https://doi.org/10.1158/1078-0432.22447638
https://doi.org/10.1158/1078-0432.22447638
Autor:
Ursula A. Matulonis, David D.L. Bowtell, J. Dirk Iglehart, Ross S. Berkowitz, John Quackenbush, Anna DeFazio, Gillian Mitchell, Helga B. Salvesen, Alexander Miron, Dariush Etemadmoghadam, Joyce Liu, Huiying Piao, Kathryn E. Daniels, Kathryn Alsop, Matthew Schwede, Ruiyang Tian, Aquila Fatima, Ronny Drapkin, Aedín C. Culhane, Nicolai Juul Birkbak, Zhigang C. Wang
XLS file, 509K, supplementary Tables 1-3: 1. Information from the Boston cohort, 2. Information from AOCS cohort, 3. Information from TCGA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045c39b55a8d1e1ed37d5d846edffb2f
https://doi.org/10.1158/1078-0432.22447641.v1
https://doi.org/10.1158/1078-0432.22447641.v1
Autor:
Ursula A. Matulonis, David D.L. Bowtell, J. Dirk Iglehart, Ross S. Berkowitz, John Quackenbush, Anna DeFazio, Gillian Mitchell, Helga B. Salvesen, Alexander Miron, Dariush Etemadmoghadam, Joyce Liu, Huiying Piao, Kathryn E. Daniels, Kathryn Alsop, Matthew Schwede, Ruiyang Tian, Aquila Fatima, Ronny Drapkin, Aedín C. Culhane, Nicolai Juul Birkbak, Zhigang C. Wang
PDF file, 366K, Supplementary Figures 1-9: 1. LOH patterns on different array platforms, 2. Allelic imbalance in LOH clusters, 3. LOH clustering breast cancer, 4. LOH and copy number prevalence in breast cancer, 5. Chemotherapy resistance and FLOH in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b042314c1e820ab1fc80ec740d489b
https://doi.org/10.1158/1078-0432.22447644
https://doi.org/10.1158/1078-0432.22447644
Autor:
William M. Gallagher, Stephen M. Hewitt, Michael J. Duffy, Goran Landberg, Robert C. Millikan, Karin Jirstrom, Desmond G. Higgins, Aedín C. Culhane, Ailís Fagan, Darran P. O'Connor, Elaine McSherry, Sallyann L. O'Brien, Elton Rexhepaj, Donal J. Brennan
Supplementary Data from Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc709e1b37fee710add153dc7f411685
https://doi.org/10.1158/1078-0432.22439725
https://doi.org/10.1158/1078-0432.22439725
Autor:
Constantine S. Mitsiades, Irene Georgakoudi, Myles Brown, Aedín C. Culhane, Rinath Jeselsohn, Yu Chen, Joseph H. Schwab, Nicholas Mitsiades, Dong Gao, Zhiyi Liu, Pallavi Awate, Shruti Sharma, Xiang Weng, Dhvanir Kansara, Ricardo de Matos Simoes, Eugen Dhimolea
Supplemental Materials & Methods and Figures 1-6. Sup. Figure 1. The effect of antiestrogens against ER+ BrCa spheroid cultures is attenuated by BMSCs. Sup. Figure 2. BMSCs attenuate the antiestrogen response of BrCa xenografts in vivo. Sup. Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2592e0493168e412c12d5dcb71bf783d
https://doi.org/10.1158/0008-5472.22427449
https://doi.org/10.1158/0008-5472.22427449
Autor:
Ursula A. Matulonis, David D.L. Bowtell, J. Dirk Iglehart, Ross S. Berkowitz, John Quackenbush, Anna DeFazio, Gillian Mitchell, Helga B. Salvesen, Alexander Miron, Dariush Etemadmoghadam, Joyce Liu, Huiying Piao, Kathryn E. Daniels, Kathryn Alsop, Matthew Schwede, Ruiyang Tian, Aquila Fatima, Ronny Drapkin, Aedín C. Culhane, Nicolai Juul Birkbak, Zhigang C. Wang
Purpose: High-grade serous cancer (HGSC) is the most common cancer of the ovary and is characterized by chromosomal instability. Defects in homologous recombination repair (HRR) are associated with genomic instability in HGSC, and are exploited by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790df936eab72409fb48fed5cee53528
https://doi.org/10.1158/1078-0432.c.6521154.v1
https://doi.org/10.1158/1078-0432.c.6521154.v1
Autor:
William M. Gallagher, Stephen M. Hewitt, Michael J. Duffy, Goran Landberg, Robert C. Millikan, Karin Jirstrom, Desmond G. Higgins, Aedín C. Culhane, Ailís Fagan, Darran P. O'Connor, Elaine McSherry, Sallyann L. O'Brien, Elton Rexhepaj, Donal J. Brennan
Purpose: Survivin (BIRC5) is a promising tumor biomarker. Conflicting data exist on its prognostic effect in breast cancer. These data may at least be partly due to the manual interpretation of immunohistochemical staining, especially as survivin can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097d0b8d77cb67ee1c38b5d1df670935
https://doi.org/10.1158/1078-0432.c.6517153.v1
https://doi.org/10.1158/1078-0432.c.6517153.v1
Autor:
Constantine S. Mitsiades, Irene Georgakoudi, Myles Brown, Aedín C. Culhane, Rinath Jeselsohn, Yu Chen, Joseph H. Schwab, Nicholas Mitsiades, Dong Gao, Zhiyi Liu, Pallavi Awate, Shruti Sharma, Xiang Weng, Dhvanir Kansara, Ricardo de Matos Simoes, Eugen Dhimolea
Although hormonal therapy (HT) inhibits the growth of hormone receptor–positive (HR+) breast and prostate cancers, HT resistance frequently develops within the complex metastatic microenvironment of the host organ (often the bone), a setting poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb0100e3894c340d1a10b497f582e965
https://doi.org/10.1158/0008-5472.c.6512674.v1
https://doi.org/10.1158/0008-5472.c.6512674.v1
Autor:
John Quackenbush, Aedín C. Culhane
Supplementary Tables, Figures and Methods from Confounding Effects in “A Six-Gene Signature Predicting Breast Cancer Lung Metastasis”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034306a7ff1a4eb3f29f4f0e53c378c5
https://doi.org/10.1158/0008-5472.22377866
https://doi.org/10.1158/0008-5472.22377866