Výsledky vyhledávání - "Adya Saran Sinha"

Akademický článek

Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation

Autor: Miho Watanabe, Adya Saran Sinha, Yohei Shinmyo, Atsuo Fukuda

Publikováno v: Frontiers in Molecular Neuroscience, Vol 17 (2024)

Corticotropin-releasing hormone (CRH) neurons play an important role in the regulation of neuroendocrine responses to stress. The excitability of CRH neurons is regulated by inhibitory GABAergic inputs. However, it is unclear when GABAergic regulatio

Externí odkaz: https://doaj.org/article/210707cbe1c4462e984146e135a8d94c

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Akademický článek

WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K+ conductance in layer V pyramidal neurons of mouse medial prefrontal cortex

Autor: Adya Saran Sinha, Tianying Wang, Miho Watanabe, Yasushi Hosoi, Eisei Sohara, Tenpei Akita, Shinichi Uchida, Atsuo Fukuda

Publikováno v: Frontiers in Molecular Neuroscience, Vol 15 (2022)

The with-no-lysine (WNK) family of serine-threonine kinases and its downstream kinases of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and oxidative stress-responsive kinase-1 (OSR1) may regulate intracellular Cl− homeostasis through phosp

Externí odkaz: https://doaj.org/article/3e1185f64de744b69d71d7b650f7dd6f

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Akademický článek

A subpopulation of agouti-related peptide neurons exciting corticotropin-releasing hormone axon terminals in median eminence led to hypothalamic-pituitary-adrenal axis activation in response to food restriction

Autor: Ruksana Yesmin, Miho Watanabe, Adya Saran Sinha, Masaru Ishibashi, Tianying Wang, Atsuo Fukuda

Publikováno v: Frontiers in Molecular Neuroscience, Vol 15 (2022)

The excitatory action of gamma-aminobutyric-acid (GABA) in the median-eminence (ME) led to the steady-state release of corticotropin-releasing hormone (CRH) from CRH axon terminals, which modulates the hypothalamic-pituitary-adrenal (HPA) axis. Howev

Externí odkaz: https://doaj.org/article/d1681886b6214344b69e8ce8f78713b8

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Akademický článek

Alterations of GABAergic Neuron-Associated Extracellular Matrix and Synaptic Responses in Gad1-Heterozygous Mice Subjected to Prenatal Stress

Autor: Tianying Wang, Adya Saran Sinha, Tenpei Akita, Yuchio Yanagawa, Atsuo Fukuda

Publikováno v: Frontiers in Cellular Neuroscience, Vol 12 (2018)

Exposure to prenatal stress (PS) and mutations in Gad1, which encodes GABA synthesizing enzyme glutamate decarboxylase (GAD) 67, are the primary risk factors for psychiatric disorders associated with abnormalities in parvalbumin (PV)-positive GABAerg

Externí odkaz: https://doaj.org/article/79071e270f6d4feea781a79d2056aa92

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