Zobrazeno 1 - 10
of 3 025
pro vyhledávání: '"Advanced rectal cancer"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The use of neoadjuvant chemoradiotherapy (neoCRT) followed by surgery has markedly enhanced the quality of survival in patients suffering from local advanced rectal cancer (LARC). Enhancing this treatment requires a deep understan
Externí odkaz:
https://doaj.org/article/fef696bc499c4045815bb5c1fb0be79d
Autor:
Yoshinori Kagawa, Koji Ando, Mamoru Uemura, Jun Watanabe, Koji Oba, Yasunori Emi, Nobuhisa Matsuhashi, Naoki Izawa, Osamu Muto, Tatsuya Kinjo, Ichiro Takemasa, Eiji Oki
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 6, Pp 1067-1075 (2024)
Abstract Aim To evaluate the feasibility and safety of total neoadjuvant therapy with long‐course chemoradiotherapy followed by consolidation chemotherapy in Japanese patients with locally advanced rectal cancer. Methods This prospective, multicent
Externí odkaz:
https://doaj.org/article/3d67fb3ae60f4273881d57e185a2000d
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 1425-1433 (2024)
Ji Yang,1,* Zhenyu Ding,2,* Ying Yu,1 Junde Liu,1 Shuang Song,1 Zhendong Zheng,2 Huiying Yu1 1Basic Medicine Laboratory, General Hospital of Northern Theater Command, Shenyang, 110016, People’s Republic of China; 2Department of Clinical Onc
Externí odkaz:
https://doaj.org/article/a252a2a254ed4661a979861fec15c2bd
Autor:
Cheng Cai, Xia Zhang, Xiaonan Sun, Huogang Wang, Engeng Chen, Li Chen, Benxing Gu, Jianping Wang, Xuefeng Huang, Weifeng Lao, Xiaowei Wang, Min Chen, Shubo Ding, Jinlin Du, Zhangfa Song
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Neoadjuvant chemoradiotherapy followed by total mesorectal excision is a standard treatment for locally advanced rectal cancer. Mismatch repair-deficient locally advanced rectal cancer (LARC) was highly sensitive to PD-1 blockade.
Externí odkaz:
https://doaj.org/article/298fbfc86d9f426ea7c57f5b038fe729
Autor:
Tianan Guo, Kai Liu, Yang Guo, Huan Zhang, Zhonglin Zhu, Dan Huang, Sanjun Cai, Tong Tong, Xiaoyan Zhou, Ye Xu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Locally advanced rectal cancer (LARC) poses unique challenges in treatment, with current neoadjuvant chemoradiotherapy (NA-CRT) showing limitations. The CapeOX regimen emerges as a potential less aggressive neoadjuvant chemotherap
Externí odkaz:
https://doaj.org/article/de40eeeebe8448f28cad20691172a308
Autor:
Shuai Li, Maxiaowei Song, Jian Tie, Xianggao Zhu, Yangzi Zhang, Hongzhi Wang, Jianhao Geng, Zhiyan Liu, Xin Sui, Huajing Teng, Yong Cai, Yongheng Li, Weihu Wang
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Purpose This study aimed to use propensity score matching (PSM) to explore the long-term outcomes and failure patterns in locally advanced rectal cancer (LARC) patients with positive versus negative lateral pelvic lymph node (LPLN). Material
Externí odkaz:
https://doaj.org/article/379d96978fd0415791b9870a20867979
Autor:
Siyuan Qin, Ke Liu, Yongye Chen, Yan Zhou, Weili Zhao, Ruixin Yan, Peijin Xin, Yupeng Zhu, Hao Wang, Ning Lang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Establishing predictive models for the pathological response and lymph node metastasis in locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT) based on MRI radiomic features derived from the tumor and mesor
Externí odkaz:
https://doaj.org/article/0e4e99b0e17c4ea78ae9a77a48d578f1
Autor:
Haohua Wang, Xiang Zhang, Boyu Leng, Kunli Zhu, Shumei Jiang, Rui Feng, Xue Dou, Fang Shi, Lei Xu, Jinbo Yue
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background In locally advanced rectal cancer (LARC), optimizing neoadjuvant strategies, including the addition of concurrent chemotherapy and dose escalation of radiotherapy, is essential to improve tumor regression and subsequent implementa
Externí odkaz:
https://doaj.org/article/d0cd489441e54b52a27332ca16b55966
Autor:
Janet A. Alvarez, Qian Shi, Arvind Dasari, Julio Garcia-Aguilar, Hanna Sanoff, Thomas J. George, Theodore Hong, Greg Yothers, Philip Philip, Garth Nelson, Tareq Al Baghdadi, Olatunji B. Alese, Wini Zambare, Dana Omer, Floris S. Verheij, Aron Bercz, Min Jung Kim, James Buckley, Hannah Williams, Manju George, Reese Garcia, Phuong Gallagher, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Jamie Crawley, Ardaman Shergill, Natally Horvat, Paul B. Romesser, William Hall, J. Joshua Smith
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Recent data have demonstrated that in locally advanced rectal cancer (LARC), a total neoadjuvant therapy (TNT) approach improves compliance with chemotherapy and increases rates of tumor response compared to neoadjuvant chemoradia
Externí odkaz:
https://doaj.org/article/f410276cdec24b44bc5dee5b6d527eee
Autor:
Linlin Xiao, Shiyu Zhuo, Yuanhang Gao, Jingyi Sun, Yuting Xiao, Lu Wang, Xuan Wang, Fuyin Qu, Ming Liu, Yi Wang, Chao Gao, Jun Wang, Fengpeng Wu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThis study aims to optimize neoadjuvant radiotherapy target area for locally advanced rectal cancer (LARC) patients undergoing total neoadjuvant therapy (TNT) by examining local recurrence patterns.Methods and materialsWe retrospectively analy
Externí odkaz:
https://doaj.org/article/eb5c24ac30c647f38f6794835065e735