Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Adrina F. Varda"'
Autor:
Gloria Jeong, Joanne M. Dennis, Paul K. Witting, Hyun Bo Kim, Martin Simone, Adrina F. Varda, Benjamin S. Rayner, XiaoSuo Wang, Belal Chami, Aung Min Maw, Genevieve Fong
Publikováno v:
Archives of Biochemistry and Biophysics. 629:19-35
After acute myocardial infarction (AMI), neutrophils are recruited to the affected myocardium. Hypochlorous acid (HOCl) produced by neutrophil myeloperoxidase (MPO) damages cardiomyocytes and potentially expands the primary infarct. Rat cardiomyocyte
Publikováno v:
Free Radical Biology and Medicine. 100:S94-S95
Inflammatory bowel disease (IBD) is a chronic condition characterised by leukocyte recruitment to the gut mucosa, where MPO-mediated oxidative damage plays an important role in exacerbating tissue injury. Aim To test whether the MPO-inhibotor, 4-Meth
Autor:
Chi L. Pham, Adrina F. Varda, Paul K. Witting, Nasr Alrabadi, Margaret Sunde, Jennifer I-Chun Lai
Publikováno v:
Biophysical Journal. (2):116a
Background: Ischemic heart disease (IHD) is a leading cause of death worldwide. Pre-clinical drugs for IHD have largely failed in human clinical trials, highlighting the importance of developing vehicles to selectively deliver optimal therapeutic age