Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Adrija J. Navarro"'
Autor:
Alex Toker, Lewis C. Cantley, Volker Haucke, Olivier Elemento, Gerburg M. Wulf, Adrija J. Navarro, Renee C. Geck, Charles J. Murphy, Haibin Wang, Marcia N. Paddock, Hui Liu
Inactivation of the tumor suppressor lipid phosphatase INPP4B is common in triple-negative breast cancer (TNBC). We generated a genetically engineered TNBC mouse model deficient in INPP4B. We found a dose-dependent increase in tumor incidence in INPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357bcca46e2c93f3e33e1375b8c98521
https://doi.org/10.1158/2159-8290.c.6547936.v1
https://doi.org/10.1158/2159-8290.c.6547936.v1
Autor:
Alex Toker, Lewis C. Cantley, Volker Haucke, Olivier Elemento, Gerburg M. Wulf, Adrija J. Navarro, Renee C. Geck, Charles J. Murphy, Haibin Wang, Marcia N. Paddock, Hui Liu
Supplementary figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2605a3dcd2fe33a411d24f33e1cf3ee2
https://doi.org/10.1158/2159-8290.22535743
https://doi.org/10.1158/2159-8290.22535743
Autor:
Alex Toker, Lewis C. Cantley, Volker Haucke, Olivier Elemento, Gerburg M. Wulf, Adrija J. Navarro, Renee C. Geck, Charles J. Murphy, Haibin Wang, Marcia N. Paddock, Hui Liu
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061bbf8323e8b62dd490e1e969a4be78
https://doi.org/10.1158/2159-8290.22535740
https://doi.org/10.1158/2159-8290.22535740
Autor:
Rosy Liao, Joshua Pan, Raymond W.S. Ng, Federica Piccioni, Jonathan P. Rennhack, Ari J. Firestone, William C. Hahn, Amy Goodale, Diego Almanza, Andrew J. Aguirre, John A. Bachman, Emma Pailler, David E. Root, Srivatsan Raghavan, Tina L. Yuan, Mukta Bagul, Nathanael S. Gray, Alfredo Gonzalez, Yenarae Lee, Jason J. Kwon, Katherine H. Walsh, Nancy Dumont, Timothy L. Bosse, Behnam Nabet, Francisca Vazquez, Jeff Settleman, Aviad Tsherniak, Joshua M. Dempster, Adrija J. Navarro, Maneesha Thaker, Rita Sulahian
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 118-134.e8 (2019)
Summary: The mitogen-activated protein kinase (MAPK) pathway is a critical effector of oncogenic RAS signaling, and MAPK pathway inhibition may be an effective combination treatment strategy. We performed genome-scale loss-of-function CRISPR-Cas9 scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01aa685e87c2fe16e8fa52aa6b0efad
http://www.sciencedirect.com/science/article/pii/S2211124719311520
http://www.sciencedirect.com/science/article/pii/S2211124719311520
Autor:
Hui Liu, Lewis C. Cantley, Marcia N. Paddock, Haibin Wang, Charles J. Murphy, Olivier Elemento, Volker Haucke, Renee C. Geck, Gerburg M. Wulf, Adrija J. Navarro, Alex Toker
Publikováno v:
Cancer Discov
Inactivation of the tumor suppressor lipid phosphatase INPP4B is common in triple-negative breast cancer (TNBC). We generated a genetically engineered TNBC mouse model deficient in INPP4B. We found a dose-dependent increase in tumor incidence in INPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928f26e2c1bfb46de4bad8154de6cb67
https://pubmed.ncbi.nlm.nih.gov/32513774
https://pubmed.ncbi.nlm.nih.gov/32513774