Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Adrienne Vancura"'
Autor:
Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Taisia Polidori, Hugo Guillen-Ramirez, Ante Mihaljevic, Bernard Mefi Merlin, Lia Mela, Eugenio Zoni, Lusine Hovhannisyan, Finn McCluggage, Matúš Medo, Giulia Basile, Dominik F. Meise, Sandra Zwyssig, Corina Wenger, Kyriakos Schwarz, Adrienne Vancura, Núria Bosch-Guiteras, Álvaro Andrades, Ai Ming Tham, Michaela Roemmele, Pedro P. Medina, Adrian F. Ochsenbein, Carsten Riether, Marianna Kruithof-de Julio, Yitzhak Zimmer, Michaela Medová, Deborah Stroka, Archa Fox, Rory Johnson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Long noncoding RNAs (lncRNAs) are linked to cancer via pathogenic changes in their expression levels. Yet, it remains unclear whether lncRNAs can also impact tumour cell fitness via function-altering somatic “driver” mutations. To search
Externí odkaz:
https://doaj.org/article/ac68b1f51d77424ab680971f8fdf0575
Autor:
Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Taisia Polidori, Hugo Guillen-Ramirez, Ante Mihaljevic, Bernard Mefi Merlin, Lia Mela, Eugenio Zoni, Lusine Hovhannisyan, Finn McCluggage, Matúš Medo, Giulia Basile, Dominik F. Meise, Sandra Zwyssig, Corina Wenger, Kyriakos Schwarz, Adrienne Vancura, Núria Bosch-Guiteras, Álvaro Andrades, Ai Ming Tham, Michaela Roemmele, Pedro P. Medina, Adrian F. Ochsenbein, Carsten Riether, Marianna Kruithof-de Julio, Yitzhak Zimmer, Michaela Medová, Deborah Stroka, Archa Fox, Rory Johnson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4e6d43c141ad486fbe88bece10724bab
Autor:
Adrienne Vancura, Alejandro H. Gutierrez, Thorben Hennig, Carlos Pulido-Quetglas, Frank J. Slack, Rory Johnson, Simon Haefliger
Publikováno v:
Non-Coding RNA, Vol 8, Iss 6, p 82 (2022)
Evolutionary conservation is a measure of gene functionality that is widely used to prioritise long noncoding RNAs (lncRNA) in cancer research. Intriguingly, while updating our Cancer LncRNA Census (CLC), we observed an inverse relationship between y
Externí odkaz:
https://doaj.org/article/add39e3887884a82aced286ad7e35274
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6
Autor:
Aditi Singh, Adrienne Vancura, Rafal K Woycicki, Daniel J Hogan, Alan G Hendrick, Mariusz Nowacki
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209707 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0206667.].
Externí odkaz:
https://doaj.org/article/4520f2b883b3475891fa81bfb205b3d9
Autor:
Aditi Singh, Adrienne Vancura, Rafal K Woycicki, Daniel J Hogan, Alan G Hendrick, Mariusz Nowacki
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206667 (2018)
5-methylcytosine DNA methylation regulates gene expression and developmental programming in a broad range of eukaryotes. However, its presence and potential roles in ciliates, complex single-celled eukaryotes with germline-somatic genome specializati
Externí odkaz:
https://doaj.org/article/4805bb1580ff418c9f9c1a793f850174
Autor:
Ozgur Oksuz, Jonathan E Henninger, Robert Warneford-Thomson, Ming M Zheng, Hailey Erb, Kalon J Overholt, Susana Wilson Hawken, Salman F Banani, Richard Lauman, Adrienne Vancura, Anne L Robertson, Nancy M Hannett, Tong I Lee, Leonard I. Zon, Roberto Bonasio, Richard A. Young
SummaryTranscription factors (TFs) orchestrate the gene expression programs that define each cell’s identity. The canonical TF accomplishes this with two domains, one that binds specific DNA sequences and the other that binds protein coactivators o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26928fddc2278ca573e0a0d65d77f09
https://doi.org/10.1101/2022.09.27.509776
https://doi.org/10.1101/2022.09.27.509776
Autor:
Dominik F. Meise, Lia Mela, Marianna Kruithof-de Julio, Kyriakos Schwarz, Hugo Guillen-Ramirez, Lusine Hovhannisyan, Yitzhak Zimmer, Eugenio Zoni, Núria Bosch-Guiteras, Sunandini Ramnarayanan, Bernard Merlin, Taisia Polidori, Isabel Büchi, Corina Wenger, Giulia Basile, Andrés Lanzós, Matúš Medo, Adrienne Vancura, Finn McCluggage, Michaela Medová, Archa H. Fox, Roberta Esposito, Sandra Zwyssig, Rory Johnson, Deborah Stroka
Long noncoding RNAs (lncRNAs) can act as tumour suppressors or oncogenes to repress/promote tumour cell proliferation via RNA-dependent mechanisms. Recently, genome sequencing has identified elevated densities of tumour somatic single nucleotide vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e293e8c05f0041dcb63c091fad007b
https://doi.org/10.21203/rs.3.rs-1481666/v1
https://doi.org/10.21203/rs.3.rs-1481666/v1
Autor:
Xin Wang, Hugo A. Guillen-Ramirez, Dominik F. Meise, Adrienne Vancura, Juliette Schlatter, Pedro P. Medina, Paulina Schaerer, Irene Carrozzo, Panagiotis Chouvardas, Carsten Riether, Emily S. Westemeier, Taisia Polidori, Stefan Forster, Rory Johnson, Carlos Pulido-Quetglas, Patrick C. Ma, Dylan Harvey, Sebastian Ullrich, Adrian F. Ochsenbein, Michaela Roemmele, Simon Haefliger, Andrea Kobel, Lina Zhu, Alvaro Andrades, Roberta Esposito, Andrés Lanzós, Giulia Basile, Ivan Martinez
Long noncoding RNAs (lncRNAs) are widely dysregulated in cancer, yet their functional roles in cellular disease hallmarks remain unclear. Here we employ pooled CRISPR deletion to perturb all 831 lncRNAs in KRAS-mutant non-small cell lung cancer (NSCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0de829a8c58d35eb3998b4084ae716a
https://doi.org/10.1101/2021.10.19.464956
https://doi.org/10.1101/2021.10.19.464956
Autor:
Andrés Lanzós, Núria Bosch, Monica Torres, Rory Johnson, Simon Haefliger, Alejandro Hionides Gutierrez, Adrienne Vancura
Publikováno v:
Vancura, Adrienne; Lanzós, Andrés; Bosch-Guiteras, Núria; Esteban, Mònica Torres; Gutierrez, Alejandro H; Haefliger, Simon; Johnson, Rory (2021). Cancer LncRNA Census 2 (CLC2): an enhanced resource reveals clinical features of cancer lncRNAs. NAR cancer, 3(2), zcab013. Oxford University Press 10.1093/narcan/zcab013
NAR Cancer
NAR Cancer
Long non-coding RNAs (lncRNAs) play key roles in cancer and are at the vanguard of precision therapeutic development. These efforts depend on large and high-confidence collections of cancer lncRNAs. Here, we present the Cancer LncRNA Census 2 (CLC2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d275372a83ee1ec6209f34e00bf30cb0
https://boris.unibe.ch/159403/1/zcab013.pdf
https://boris.unibe.ch/159403/1/zcab013.pdf