Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Adrienne R Hanson"'
Autor:
Joanna L Gillis, Josephine A Hinneh, Natalie K Ryan, Swati Irani, Max Moldovan, Lake-Ee Quek, Raj K Shrestha, Adrienne R Hanson, Jianling Xie, Andrew J Hoy, Jeff Holst, Margaret M Centenera, Ian G Mills, David J Lynn, Luke A Selth, Lisa M Butler
Publikováno v:
eLife, Vol 10 (2021)
Alterations to the androgen receptor (AR) signalling axis and cellular metabolism are hallmarks of prostate cancer. This study provides insight into both hallmarks by uncovering a novel link between AR and the pentose phosphate pathway (PPP). Specifi
Externí odkaz:
https://doaj.org/article/7b041890c6d2431cb95c6683b6ee5211
Autor:
Luke A. Selth, Wayne D. Tilley, Lisa M. Butler, Felix Y. Feng, Gregory J. Goodall, Amina Zoubeidi, Elizabeth D. Williams, Hayley S. Ramshaw, Kim N. Chi, Eric A. Klein, Robert B. Den, Ashley E. Ross, R. Jeffrey Karnes, Robert B. Jenkins, Elai Davicioni, Esmaeil Ebrahimie, Noor A. Lokman, Heather K. Armstrong, Marie A. Pickering, Adrienne R. Hanson, Shuang G. Zhao, Scott L. Townley, Qingqing Wang, Iza Denis, Rayzel C. Fernandes, Philip A. Gregory, Rajdeep Das
Serum levels of miR-194 have been reported to predict prostate cancer recurrence after surgery, but its functional contributions to this disease have not been studied. Herein, it is demonstrated that miR-194 is a driver of prostate cancer metastasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3b2d3d7dede2dd0bb742c8f4f64e38
https://doi.org/10.1158/0008-5472.c.6509570
https://doi.org/10.1158/0008-5472.c.6509570
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 66KB, Immunohistochemistry methodology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf889859efab3c95aa4266aa0c2a5ef
https://doi.org/10.1158/1078-0432.22454438.v1
https://doi.org/10.1158/1078-0432.22454438.v1
Autor:
Lisa M. Butler, Johannes V. Swinnen, Luke A. Selth, Massimo Loda, Andrew M. Scott, Wayne D. Tilley, Ian G. Mills, Nicolas H. Voelcker, Anna Cifuentes-Rius, Andreas Evdokiou, Elizabeth D. Williams, Rita Derua, Etienne Waelkens, Vasilios Panagopoulos, Katarzyna Bloch, Ryan Carelli, Adrienne R. Hanson, Terence Tieu, Chui Yan Mah, Joanna L. Gillis, Natalie K. Ryan, Emma Evergren, Clyde Bango, Paolo M. Chetta, Giorgia Zadra, Ingrid J.G. Burvenich, Jonas Dehairs, Irene Zinonos, Deanna C. Miller, Zeyad D. Nassar, Jelle Machiels, Julia S. Scott, Margaret M. Centenera
Supplementary figures 1-9 and legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b655f76513f6d4faaf9386864d66a65
https://doi.org/10.1158/0008-5472.22429005
https://doi.org/10.1158/0008-5472.22429005
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 92KB, (A) PC-3 and (B) LNCaP prostate cancer cells were cultured in medium containing vehicle or 40nM 17-AAG for 96 hours, stained with propidium iodide and analysed by flow cytometry. Cell cycle distibution was determined using FlowJo soft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6855232b4e35afdf18005a9a72c5edf1
https://doi.org/10.1158/1078-0432.22454450
https://doi.org/10.1158/1078-0432.22454450
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 70KB, Primary antibodies used for immunoblotting and immunohistochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb522e66dc63023754d621d624a0c76
https://doi.org/10.1158/1078-0432.22454441
https://doi.org/10.1158/1078-0432.22454441
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 158KB, Hsp90 inhibitors cause dose dependent inhibition of growth and induction of death in LNCaP prostate cancer cells. LNCaP cells were cultured in medium containing the indicated doses of (A&B) AUY922, (C&D) HSP990 or (E&F) 17-AAG. Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b73902f6d5b2161c4474f70f2aceda0
https://doi.org/10.1158/1078-0432.22454453
https://doi.org/10.1158/1078-0432.22454453
Autor:
Lisa M. Butler, Johannes V. Swinnen, Luke A. Selth, Massimo Loda, Andrew M. Scott, Wayne D. Tilley, Ian G. Mills, Nicolas H. Voelcker, Anna Cifuentes-Rius, Andreas Evdokiou, Elizabeth D. Williams, Rita Derua, Etienne Waelkens, Vasilios Panagopoulos, Katarzyna Bloch, Ryan Carelli, Adrienne R. Hanson, Terence Tieu, Chui Yan Mah, Joanna L. Gillis, Natalie K. Ryan, Emma Evergren, Clyde Bango, Paolo M. Chetta, Giorgia Zadra, Ingrid J.G. Burvenich, Jonas Dehairs, Irene Zinonos, Deanna C. Miller, Zeyad D. Nassar, Jelle Machiels, Julia S. Scott, Margaret M. Centenera
The androgen receptor (AR) is the key oncogenic driver of prostate cancer, and despite implementation of novel AR targeting therapies, outcomes for metastatic disease remain dismal. There is an urgent need to better understand androgen-regulated cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b642b63ff4d8ef75df0e915e7947c600
https://doi.org/10.1158/0008-5472.c.6513210.v1
https://doi.org/10.1158/0008-5472.c.6513210.v1
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 581KB, Representative (A) Ki67 and (B) cleaved caspase-3 immunostaining in tumors cultured for 48 hours with vehicle control or increasing doses of Hsp90 inhibitors as indicated. Bar = 50�m.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85952675a728c46ff45193719f49fe45
https://doi.org/10.1158/1078-0432.22454444.v1
https://doi.org/10.1158/1078-0432.22454444.v1
Autor:
Luke A. Selth, Wayne D. Tilley, Lisa M. Butler, Felix Y. Feng, Gregory J. Goodall, Amina Zoubeidi, Elizabeth D. Williams, Hayley S. Ramshaw, Kim N. Chi, Eric A. Klein, Robert B. Den, Ashley E. Ross, R. Jeffrey Karnes, Robert B. Jenkins, Elai Davicioni, Esmaeil Ebrahimie, Noor A. Lokman, Heather K. Armstrong, Marie A. Pickering, Adrienne R. Hanson, Shuang G. Zhao, Scott L. Townley, Qingqing Wang, Iza Denis, Rayzel C. Fernandes, Philip A. Gregory, Rajdeep Das
This files contains 1 Supplementary Table and 11 Supplementary Figures. The Supplementary Table shows Univariate and multivariate Cox proportional hazard analysis of prostate tumor levels of miR-194 and Gleason score/grade in relation to recurrence-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da95fba5ebc8ea94bff279a8e4402e6e
https://doi.org/10.1158/0008-5472.22416509
https://doi.org/10.1158/0008-5472.22416509