Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adrienne N. Fontan"'
Publikováno v:
The Journal of Cell Biology
Roy et al. highlight a harmful cross-talk that can arise between spindle assembly checkpoint silencing and chromosome biorientation due to the involvement of protein phosphatase 1 in both the processes.
Accurate chromosome segregation during cel
Accurate chromosome segregation during cel
Publikováno v:
Curr Biol
SummaryAccurate chromosome segregation during cell division requires amphitelic chromosome attachment to the spindle apparatus. It is ensured by the combined activity of the Spindle Assembly Checkpoint1 (SAC), a signaling mechanism that delays anapha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8daaa3184373f0985446a4a39d712322
https://doi.org/10.1101/2021.01.05.425459
https://doi.org/10.1101/2021.01.05.425459
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
During mitosis, the Spindle Assembly Checkpoint (SAC) maintains genome stability while also ensuring timely anaphase onset. To maintain genome stability, the SAC must be strong to delay anaphase even if just one chromosome is unattached, but for time
SummaryThe Spindle Assembly Checkpoint (SAC) maintains genome stability while enabling timely anaphase onset. To maintain genome stability, the SAC must be strong so that it delays cell division even if one chromosome is unattached, but for timely an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99038d2b221786413885e4bd02102c3b
https://doi.org/10.1101/2020.01.07.897876
https://doi.org/10.1101/2020.01.07.897876
Accurate chromosome segregation during cell division requires that the pair of sister kinetochores on each chromosome attach to microtubules originating from opposite spindle poles. This is ensured by the combined action of the Spindle Assembly Check
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbc2fe63079cf6fd837c36c5cd23a21
https://doi.org/10.1101/459594
https://doi.org/10.1101/459594
Autor:
Anand Banerjee, Adrienne N. Fontan, Palak Sekhri, David M Kern, John J. Tyson, Ian P. Whitney, Iain M. Cheeseman, Ajit P. Joglekar, Christopher S. Chen
SummarySwitch-like activation of the Spindle Assembly Checkpoint (SAC) is critical for accurate chromosome segregation during cell division. To determine the mechanisms that implement it, we engineered an ectopic, kinetochore-independent SAC activato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d104dbfc571ec6ef546d59905df484
Autor:
Palak Sekhri, Geert J. P. L. Kops, Anand Banerjee, John J. Tyson, Carlos Sacristan, Ian P. Whitney, Ajit P. Joglekar, Adrienne N. Fontan, David M Kern, Iain M. Cheeseman, Chu Chen
Publikováno v:
Current Biology, 29(1), 104-119.e10. Cell Press
Switch-like activation of the Spindle Assembly Checkpoint (SAC) is critical for accurate chromosomes segregation and for cell division in a timely manner. To determine the mechanisms that achieve this, we engineered an ectopic, kinetochore-independen