Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adrienne M. Orriols"'
Autor:
Hugh Shirley, Adrienne M. Orriols, Dylan Hogan, Kingford Chimfwembe, Alinaswe Bwalya, Kaala Sibbuku, Janelle Lardizabal, Sophie Tillotson, Grace Grifferty, Philip Espinola Coombs, Richard Wamai
Publikováno v:
Frontiers in Tropical Diseases, Vol 5 (2024)
Lymphatic filariasis (LF) is a neglected tropical disease caused by microfilariae of the Wuchereria and Brugia genus and spread by mosquitoes. Chronic infection and associated morbidity leads to poor psychosocial and economic outcomes. LF elimination
Externí odkaz:
https://doaj.org/article/54afb37e2ed842b5a1915748650a80b9
Autor:
Lauren R. Begg, Adrienne M. Orriols, Markella Zannikou, Chen Yeh, Pranathi Vadlamani, Deepak Kanojia, Rosemary Bolin, Sara F. Dunne, Sanjeev Balakrishnan, Roman Camarda, Diane Roth, Nicolette A. Zielinski-Mozny, Christina Yau, Athanassios Vassilopoulos, Tzu-Hsuan Huang, Kwang-Youn A. Kim, Dai Horiuchi
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-17 (2024)
Abstract Background Understanding why some triple-negative breast cancer (TNBC) patients respond poorly to existing therapies while others respond well remains a challenge. This study aims to understand the potential underlying mechanisms distinguish
Externí odkaz:
https://doaj.org/article/bbe12d3b38a147d5bf67e56921985ad3
Autor:
Grace Grifferty, Hugh Shirley, Katherine O'Brien, Jason L Hirsch, Adrienne M Orriols, Kiira Lani Amechi, Joshua Lo, Neeharika Chanda, Sarra El Hamzaoui, Jorja Kahn, Samantha V Yap, Kyleigh E Watson, Christina Curran, Amina Atef AbdelAlim, Neeloy Bose, Alissa Link Cilfone, Richard Wamai
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 6, p e0011358 (2023)
BackgroundThe leishmaniases are a group of four vector-borne neglected tropical diseases caused by 20 species of protozoan parasites of the genus Leishmania and transmitted through a bite of infected female phlebotomine sandflies. Endemic in over 100
Externí odkaz:
https://doaj.org/article/f0f00acb5d9143a1a13497b639d17f5b
Autor:
Athanassios Vassilopoulos, Alesia Vialichka, Erica Fleming-Trujillo, Young Ah Goo, Massimo Cristofanilli, Matthew R. Clutter, Pranathi Vadlamani, Marc L. Mendillo, Jessica N. Perrino, Sara Fernandez Dunne, Michelle Velyunskiy, Diane Roth, Adrienne M. Orriols, Rosemary Bolin, Lauren Begg, Byoung-Kyu Cho, Ratika Kunder, Deepak Kanojia, Nicolette A. Zielinski-Mozny, Dai Horiuchi
Publikováno v:
Cell Chem Biol
Triple-negative breast cancer (TNBC) is the breast cancer subtype with the poorest clinical outcome. The PIM family of kinases has emerged as a factor that is both overexpressed in TNBC and associated with poor outcomes. Preclinical data suggest that