Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adrienne J. Werth"'
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractIntroduction Dermatomyositis, systemic and cutaneous lupus erythematosus have a significantly higher prevalence in women than men, emphasizing the relevance of exploring the relationship between sex hormones and autoimmune skin diseases. This
Externí odkaz:
https://doaj.org/article/2fa1a111add94225bbb1a88cec9e8564
Autor:
Helen Toma, Julia A. Elvin, Brennan Decker, Ethan Sokol, Kevin Jon Williams, Shakti H. Ramkissoon, Dean Pavlick, Brian M. Alexander, Meagan Montesion, Erik A. Williams, Douglas I. Lin, Jeffrey S. Ross, Nikunj Shah, Jeffrey M. Venstrom, Adrienne J Werth, Lee A. Albacker, Radwa Sharaf
Publikováno v:
JCO Precision Oncology. :955-971
PURPOSE Leiomyosarcoma (LMS) harbors frequent mutations in TP53 and RB1 but few actionable genomic alterations. Here, we searched for recurrent actionable genomic alterations in LMS that occur in the absence of common untreatable oncogenic drivers. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f96b80438f8467d3d63f9ce80e9aa66
https://doi.org/10.1200/po.20.00040
https://doi.org/10.1200/po.20.00040
Autor:
Jeff M Venstrom, Molly McLaughlin-Drubin, Jonathan Keith Killian, Brian M. Alexander, Radwa Sharaf, Nikunj Shah, Helen Toma, Jeffrey S. Ross, Rachel L. Erlich, Mark C. Mochel, Adrienne J Werth, Amanda Hemmerich, Julia A. Elvin, Dean Pavlick, Kevin Jon Williams, Ethan Sokol, Douglas I. Lin, Julie Y. Tse, Eric Allan Severson, Shakti H. Ramkissoon, Meagan Montesion, Erik A. Williams, Natalie Danziger
Publikováno v:
JCO Precision Oncology
PURPOSE Vulvar squamous cell carcinoma (vSCC) encompasses two predominant variants: one associated with detectable high-risk strains of human papillomavirus (hrHPV) and a second form often occurring in the context of chronic dermatitis in postmenopau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d20e61c0493ccd1c089d4c50be4031
https://doi.org/10.1200/po.19.00406
https://doi.org/10.1200/po.19.00406
Autor:
Erik A. Williams, Meagan Montesion, Vadim Lincoln, Julie Y. Tse, Matthew C. Hiemenz, Douglas A. Mata, Bhamini B. Shah, Adebowale Shoroye, Brian M. Alexander, Adrienne J. Werth, Kathleen Foley-Peres, Riza R. Milante, Jeffrey S. Ross, Shakti H. Ramkissoon, Kevin Jon Williams, Laura J. Adhikari, Rosemary E. Zuna, Philip E. LeBoit, Douglas I. Lin, Julia A. Elvin
Publikováno v:
The American journal of surgical pathology. 46(6)
Inactivating mutations in tumor suppressor genes TP53 and RB1 are considered central drivers in leiomyosarcomas (LMSs). In high-risk human papillomavirus (HPV)-related tumors, a similar functional outcome is achieved through oncoproteins E6 and E7, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c234af1feebaf71da7e5c32f4e056d
https://pubmed.ncbi.nlm.nih.gov/35034043
https://pubmed.ncbi.nlm.nih.gov/35034043
Autor:
Shakti H. Ramkissoon, Helen Toma, Adrienne J Werth, Nikunj Shah, Julia A. Elvin, Douglas I. Lin, Brian M. Alexander, Jeff M Venstrom, Jeffrey S. Ross, Ethan Sokol, Dean Pavlick, Radwa Sharaf, Lee A. Albacker, Brennan Decker, Meagan Montesion, Erik A. Williams
PurposeLeiomyosarcomas (LMS) harbor frequent inactivation of TP53 and RB1, and extensive DNA copy number alterations. Here, we describe a distinct recurrent genomic signature in TP53/RB1-wildtype uterine LMS.MethodsTissues from 276,645 unique advance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e6e77315a6fc45ac8d01986cac35d1
https://doi.org/10.1101/2020.03.02.973305
https://doi.org/10.1101/2020.03.02.973305
Autor:
Douglas A. Mata, Richard S.P. Huang, Kevin Jon Williams, Meagan Montesion, Shakti H. Ramkissoon, Erik A. Williams, Brian M. Alexander, Julia A. Elvin, Adrienne J Werth, Douglas I. Lin, Justin Newberg
Publikováno v:
Gynecologic Oncology. 162:S85
Objectives: Among women with high-risk human papillomavirus (hrHPV) detected in cervical swabs, the distribution of hrHPV types is known to differ by racial/ethnic group, with East and West Africans and North Americans of African ancestry1 showing ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70cb6ca86518fd72764983c41fff8828
https://doi.org/10.1016/s0090-8258(21)00802-7
https://doi.org/10.1016/s0090-8258(21)00802-7
Autor:
Jonathan Keith Killian, Ethan Sokol, Jeffrey S. Ross, Adrienne J Werth, Radwa Sharaf, J.A. Elvin, Nikunj Shah, Meagan Montesion, V.A. Miller, Erik A. Williams, Douglas I. Lin, Julie Y. Tse, Natalie Danziger, Dean Pavlick
Publikováno v:
Gynecologic Oncology. 159:32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b324b5dcc04b5590fb0f1cdb1b129f
https://doi.org/10.1016/j.ygyno.2020.06.066
https://doi.org/10.1016/j.ygyno.2020.06.066
Autor:
Meagan Montesion, Erik A. Williams, Douglas A Lin, Dean Pavlick, Ethan Sokol, Jo-Anne Vergilio, Nikunj Shah, Natalie Danziger, Adrienne J Werth, Jeffrey S. Ross, Jonathan Keith Killian, Julia A. Elvin, Vincent A. Miller
Publikováno v:
Molecular Cancer Therapeutics. 18:B091-B091
Introduction: One major form of vulvar squamous cell carcinoma (vSCC) is associated with detectable high-risk strains of human papillomavirus (hrHPV) and is often accompanied by usual-type vulvar intraepithelial neoplasia (VIN). The second major form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ad0993ab13d88f0b0be741b517efaa
https://doi.org/10.1158/1535-7163.targ-19-b091
https://doi.org/10.1158/1535-7163.targ-19-b091
Autor:
Bernice M. Benoit, Brian S. Kim, Junko Takeshita, Neha Jariwala, Alain H. Rook, Timothy M. Whelan, Christopher J. Miller, Daniel W. McVicar, Lisa Zhu, Maria Wysocka, Adrienne J Werth, Landon K. Oetjen, Andrea B. Troxel, Geraldine M. O’Connor, Hélène Sicard
Sezary syndrome (SS), a leukemic variant of cutaneous T-cell lymphoma (CTCL), is associated with a significantly shorter life expectancy compared to skin-restricted mycosis fungoides. Early diagnosis of SS is, therefore, key to achieving enhanced the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88eaae25bd1a88fee8197b7648cf934
Autor:
Adrienne J Werth, Christine Marshall, Tzvete Dentchev, Ryan Hick, Christopher J. Miller, Hasan Bashir, Weijie Li, John T. Seykora, Liang Zhao, Warren S. Pear, Erik A. Williams, Matthew Hanson, Thomas W. Griffin
Publikováno v:
Cancer research. 69(24)
Src family tyrosine kinases (SFK) regulate cell proliferation, and increased SFK activity is common in human carcinomas, including cutaneous squamous cell carcinomas (SCC) and its precursors. The elevated SFK activity in cutaneous SCCs was modeled us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cb964eafa0bb9e262a8533d7c8b9cb
https://pubmed.ncbi.nlm.nih.gov/19934324
https://pubmed.ncbi.nlm.nih.gov/19934324