Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Adrienne E. Sochia"'
Autor:
Michael N. Lombardo, Amy C. Anderson, Behnoush Hajian, Nigel D. Priestley, Jeremy B. Alverson, Stephanie M. Reeve, Adrienne E. Sochia, Eric W. Scocchera, Santosh Keshipeddy, Dennis L. Wright
Publikováno v:
ACS Medicinal Chemistry Letters. 7:692-696
Although classical, negatively charged antifolates such as methotrexate possess high affinity for the dihydrofolate reductase (DHFR) enzyme, they are unable to penetrate the bacterial cell wall, rendering them poor antibacterial agents. Herein, we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823d3378c243ec1a2720df94ddd56a00
https://doi.org/10.1021/acsmedchemlett.6b00120
https://doi.org/10.1021/acsmedchemlett.6b00120
Autor:
Adrienne E. Sochia, Michael N. Lombardo, Kishore Viswanathan, Amy C. Anderson, Nigel D. Priestley, Narendran G-Dayanandan, Kristen M. Lamb, Dennis L. Wright, Janet L. Paulsen, Santosh Keshipeddy, Jeremy B. Alverson, Wangda Zhou
Publikováno v:
Journal of Medicinal Chemistry
Species of Candida, primarily C. albicans and with increasing prevalence, C. glabrata, are responsible for the majority of fungal bloodstream infections that cause morbidity, especially among immune compromised patients. While the development of new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1c99e4741aeb4c234bbc8de7aab63d
https://doi.org/10.1021/jm401916j
https://doi.org/10.1021/jm401916j
Publikováno v:
Chemistry. 7:2059-2066
The covalent casting of noncovalent architectures serves to define large covalent constructs that express well-defined modes of aggregation. In the case of one-dimensional hydrogen-bonding motifs, covalent casting yields molecular strands that adopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c31ebbaf16790e011dd1cc8d69d6d4d
https://doi.org/10.1002/1521-3765(20010518)7:10<2059::aid-chem2059>3.0.co
https://doi.org/10.1002/1521-3765(20010518)7:10<2059::aid-chem2059>3.0.co
Publikováno v:
ChemInform. 33
The covalent casting of noncovalent architectures serves to define large covalent constructs that express well-defined modes of aggregation. In the case of one-dimensional hydrogen-bonding motifs, covalent casting yields molecular strands that adopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7afa128a7806ff3c0a6cf831439f8114
https://doi.org/10.1002/chin.200204278
https://doi.org/10.1002/chin.200204278
Publikováno v:
Chemistry. 7:2047-2047
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99b2724150b74745f009a0014c9d16a
https://doi.org/10.1002/1521-3765(20010518)7:10<2047::aid-chem2047>3.0.co
https://doi.org/10.1002/1521-3765(20010518)7:10<2047::aid-chem2047>3.0.co