Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Adrienne E Swanstrom"'
Autor:
Hugh C Welles, Hannah A D King, Leonard Nettey, Nicole Cavett, Jason Gorman, Tongqing Zhou, Yaroslav Tsybovsky, Renguang Du, Kaimei Song, Richard Nguyen, David Ambrozak, Amy Ransier, Chaim A Schramm, Nicole A Doria-Rose, Adrienne E Swanstrom, James A Hoxie, Celia LaBranche, David C Montefiori, Daniel C Douek, Peter D Kwong, John R Mascola, Mario Roederer, Rosemarie D Mason
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010574 (2022)
Both SIV and SHIV are powerful tools for evaluating antibody-mediated prevention and treatment of HIV-1. However, owing to a lack of rhesus-derived SIV broadly neutralizing antibodies (bnAbs), testing of bnAbs for HIV-1 prevention or treatment has th
Externí odkaz:
https://doaj.org/article/4be5c204019f42f9a419f3dd8f3193f7
Autor:
Andrea L Ferris, David W Wells, Shuang Guo, Gregory Q Del Prete, Adrienne E Swanstrom, John M Coffin, Xiaolin Wu, Jeffrey D Lifson, Stephen H Hughes
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007869 (2019)
Clonal expansion of HIV infected cells plays an important role in the formation and persistence of the reservoir that allows the virus to persist, in DNA form, despite effective antiretroviral therapy. We used integration site analysis to ask if ther
Externí odkaz:
https://doaj.org/article/5e65d44819954b439ce25fc7838a7478
Autor:
Sean P O'Brien, Adrienne E Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T Immonen, Gregory Q Del Prete, Christine M Fennessey, Jason Gorman, Kathryn E Foulds, Stephen D Schmidt, Nicole Doria-Rose, Carolyn Williamson, Theodora Hatziioannou, Paul D Bieniasz, Hui Li, George M Shaw, John R Mascola, Richard A Koup, Peter D Kwong, Jeffrey D Lifson, Mario Roederer, Brandon F Keele
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007632 (2019)
Chimeric Simian-Human Immunodeficiency Viruses (SHIVs) are an important tool for evaluating anti-HIV Env interventions in nonhuman primate (NHP) models. However, most unadapted SHIVs do not replicate well in vivo limiting their utility. Furthermore,
Externí odkaz:
https://doaj.org/article/223d0101fda54e459f18cac090f5311b
Autor:
Gregory Q Del Prete, Brandon F Keele, Jeannine Fode, Keyur Thummar, Adrienne E Swanstrom, Anthony Rodriguez, Alice Raymond, Jacob D Estes, Celia C LaBranche, David C Montefiori, Vineet N KewalRamani, Jeffrey D Lifson, Paul D Bieniasz, Theodora Hatziioannou
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006572 (2017)
Species-dependent variation in proteins that aid or limit virus replication determines the ability of lentiviruses to jump between host species. Identifying and overcoming these differences facilitates the development of animal models for HIV-1, incl
Externí odkaz:
https://doaj.org/article/6b49d622424547a9829eab904952bf7a
Autor:
Adrienne E. Swanstrom, Robert J. Gorelick, Jorden L. Welker, Fabian Schmidt, Bing Lu, Kelly Wang, William Rowe, Matthew W. Breed, Kristin E. Killoran, Joshua A. Kramer, Duncan Donohue, James D. Roser, Paul D. Bieniasz, Theodora Hatziioannou, Cathi Pyle, James A. Thomas, Charles M. Trubey, Jim Zheng, Wade Blair, Stephen R. Yant, Jeffrey D. Lifson, Gregory Q. Del Prete
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104764- (2023)
Summary: Background: Long-acting subcutaneous lenacapavir (LEN), a first-in-class HIV capsid inhibitor approved by the US FDA for the treatment of multidrug-resistant HIV-1 with twice yearly dosing, is under investigation for HIV-1 pre-exposure proph
Externí odkaz:
https://doaj.org/article/b06319c89f9342968fa2a346c4e69436
Autor:
Michael Hull, Jacob D. Estes, Randy Fast, Joshua A. Kramer, Laura Newman, Rodney Wiles, Rebecca Shoemaker, William J. Bosche, Claire Deleage, Christine M. Fennessey, Tyler Malys, James A. Thomas, Charles M. Trubey, Lorna Silipino, Vicky Coalter, Gregory Q. Del Prete, Jeffrey D. Lifson, Cathi Pyle, Duncan Donohue, Adam Wiles, Jacob Kiser, Brandon F. Keele, David R. Morcock, Adrienne E. Swanstrom, Taina T. Immonen, Kelli Oswald, Matthew W. Breed
Publikováno v:
J Clin Invest
The effectiveness of virus-specific strategies, including administered HIV-specific mAbs, to target cells that persistently harbor latent, rebound-competent HIV genomes during combination antiretroviral therapy (cART) has been limited by inefficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b7bbba818f529be5aff422e155c2c2
https://pubmed.ncbi.nlm.nih.gov/33465055
https://pubmed.ncbi.nlm.nih.gov/33465055
Autor:
Anitha Vijayagopalan, Siddhartha A. K. Datta, Adrienne E. Swanstrom, Gregory Q. Del Prete, Kelli Oswald, Bonnie J. Howell, Jeffrey D. Lifson, Rebecca Shoemaker, Julian W. Bess, Elena Chertova, Guoxin Wu, Robert J. Gorelick, Brandon F. Keele
Publikováno v:
AIDS Research and Human Retroviruses. 34:993-1001
Although effective for suppressing viral replication, combination antiretroviral treatment (cART) does not represent definitive therapy for HIV infection due to persistence of replication-competent viral reservoirs. The advent of effective cART regim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89579304f3d0396bea529cfbeef9e206
https://doi.org/10.1089/aid.2018.0075
https://doi.org/10.1089/aid.2018.0075
Autor:
Sirish Khanal, Gregory Q. Del Prete, Brandon F. Keele, Abigail Thorpe, Louis J. Picker, Julian W. Bess, Taina T. Immonen, Sean P. O’Brien, Miles P. Davenport, Adrienne E. Swanstrom, Rodman Smith, Carolyn Reid, Christine M. Fennessey, Afam A. Okoye, Jeffrey D. Lifson
Publikováno v:
J Virol
Genetically barcoded viral populations are powerful tools for evaluating the overall viral population structure as well as assessing the dynamics and evolution of individual lineages in vivo over time. Barcoded viruses are generated by inserting a sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afdd7e486e1a08d165a892a1a9e3c3a
https://europepmc.org/articles/PMC6912102/
https://europepmc.org/articles/PMC6912102/
Autor:
Lori V. Coren, Sumiti Jain, David E. Ott, Matthew W. Breed, Gregory Q. Del Prete, Matthew T. Trivett, Adrienne E. Swanstrom, Eugene V. Barsov, Jeffrey D. Lifson, Claire Deleage, Brenna J. Hill, Joshua A. Kramer, James D. Burke
Publikováno v:
Journal of Virology. 93
Adoptive cell transfer (ACT) is a powerful experimental approach to directly study T-cell-mediated immunity in vivo. In the rhesus macaque AIDS virus model, infusing simian immunodeficiency virus (SIV)-infected animals with CD8 T cells engineered to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5fb1e47941677a51aad6503285981e
https://doi.org/10.1128/jvi.00896-19
https://doi.org/10.1128/jvi.00896-19
Autor:
Shuang Guo, Andrea L. Ferris, Adrienne E. Swanstrom, Gregory Q. Del Prete, David Wells, Stephen H. Hughes, Jeffrey D. Lifson, John M. Coffin, Xiaolin Wu
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007869 (2019)
PLoS Pathogens
PLoS Pathogens
Clonal expansion of HIV infected cells plays an important role in the formation and persistence of the reservoir that allows the virus to persist, in DNA form, despite effective antiretroviral therapy. We used integration site analysis to ask if ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72c005cacdbe83c41acb2803a7ae599
https://doaj.org/article/5e65d44819954b439ce25fc7838a7478
https://doaj.org/article/5e65d44819954b439ce25fc7838a7478