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pro vyhledávání: '"Adrien Sprumont"'
Autor:
Ludivine C. Litzler, Astrid Zahn, Alexandre P. Meli, Steven Hébert, Anne-Marie Patenaude, Stephen P. Methot, Adrien Sprumont, Thérence Bois, Daisuke Kitamura, Santiago Costantino, Irah L. King, Claudia L. Kleinman, Stéphane Richard, Javier M. Di Noia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Protective antibody responses depend critically on proper B cell development and differentiation at multiple stages. Here the authors show that a protein arginine methyltransferase, Prmt5 uses multiples pathways to prevent death of immature B cells,
Externí odkaz:
https://doaj.org/article/33da862d42ce48bf82823c6742c63b37
Autor:
Adrien Sprumont, Ludivine C. Litzler, Santiago Costantino, Therence Bois, Anne-Marie Patenaude, Claudia L. Kleinman, Alexandre P. Meli, Irah L. King, Javier M. Di Noia, Astrid Zahn, Daisuke Kitamura, Steven Hébert, Stephen P. Methot, Stéphane Richard
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Mechanisms regulating B cell development, activation, education in the germinal center (GC) and differentiation, underpin the humoral immune response. Protein arginine methyltransferase 5 (Prmt5), which catalyzes most symmetric dimethyl arginine prot