Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adrien H. Cerdan"'
Autor:
Sophie Shi, Solène N. Lefebvre, Laurie Peverini, Adrien H. Cerdan, Paula Milán Rodríguez, Marc Gielen, Jean-Pierre Changeux, Marco Cecchini, Pierre-Jean Corringer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Glycine receptors are channel receptors mediating signal transduction between neurons that transit between resting and open states upon neurotransmitter binding. Here, the authors illuminate a progressive transition of opening by combining voltage-cl
Externí odkaz:
https://doaj.org/article/2f309521f60544c4a944d621a652fe13
Autor:
Adrien H. Cerdan, Laurie Peverini, Jean-Pierre Changeux, Pierre-Jean Corringer, Marco Cecchini
Publikováno v:
Science Advances
Science Advances, 2022, 8 (41), pp.eadc9340. ⟨10.1126/sciadv.adc9340⟩
Science Advances, Vol. 8, No. 41
Science Advances, 2022, 8 (41), pp.eadc9340. ⟨10.1126/sciadv.adc9340⟩
Science Advances, Vol. 8, No. 41
In-house VMD scripts for counting ion permeation events via the lateral/apical pathways over time and counting the number of chloride ions in the vestibule are provided at the following links: https://doi.org/10.5281/zenodo.6935496 and https://doi.or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178f31843a4c751dbe98363fda1dbe61
https://pubmed.ncbi.nlm.nih.gov/36240268
https://pubmed.ncbi.nlm.nih.gov/36240268
Autor:
Marco Cecchini, Adrien H. Cerdan
Publikováno v:
Structure
Structure, 2020, 28 (6), pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
Structure, Elsevier (Cell Press), 2020, 28, pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
Structure, 2020, 28 (6), pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
Structure, Elsevier (Cell Press), 2020, 28, pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
The glycine receptor (GlyR) is by far the best-characterized pentameric ligand-gated ion channel with several high-resolution structures from X-ray crystallography, cryo-EM and modeling. Nonetheless, the significance of the currently available open-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700b599a294a7708a48fd863ddcea615
https://doi.org/10.1101/2020.05.05.076802
https://doi.org/10.1101/2020.05.05.076802
Autor:
Jerome Becot, Nicolas Bosc, Adrien H. Cerdan, Mélaine A. Kuenemann, Marek Vavrusa, Olivier Sperandio
Publikováno v:
Journal of chemical information and modeling. 57(10)
Given the difficulties to identify chemical probes that can modulate protein–protein interactions (PPIs), actors in the field have started to agree on the necessity to use PPI-tailored screening chemical collections. However, which type of scaffold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ee1ec5a7fcfe0fb2d1f7bed0f021b1
https://pubmed.ncbi.nlm.nih.gov/28922596
https://pubmed.ncbi.nlm.nih.gov/28922596
Autor:
Thomas Grutter, Thierry Chataigneau, Alexandre Specht, Kate Dunning, Juline Beudez, Adrien H. Cerdan, Marco Cecchini, Laurie Peverini, Mahboubi Harkat, Nicolas Calimet, Adeline Martz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (19), pp.E3786-E3795. ⟨10.1073/pnas.1701379114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (19), pp.E3786-E3795. ⟨10.1073/pnas.1701379114⟩
International audience; Pore dilation is thought to be a hallmark of purinergic P2X receptors. The most commonly held view of this unusual process posits that under prolonged ATP exposure the ion pore expands in a striking manner from an initial smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378c9903c9a81049d416e6f6aa609029
https://doi.org/10.1073/pnas.1701379114
https://doi.org/10.1073/pnas.1701379114
Publikováno v:
Scientific Reports
Protein-protein interactions (PPIs) play vital roles in life and provide new opportunities for therapeutic interventions. In this large data analysis, 3,300 inhibitors of PPIs (iPPIs) were compared to 17 reference datasets of collectively ~566,000 co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126a7801d2d3e69a14db3e5aaa03a125